A5074398169- Temporomandibular Joint Disorders
- Musculoskeletal synovial abnormalities and treatments
- Bone Tumor Diagnosis and Treatments
- Osteoarthritis Treatment and Mechanisms
- Dental Radiography and Imaging
- Sarcoma Diagnosis and Treatment
- Oral and Maxillofacial Pathology
- Medical and Biological Sciences
- Inflammatory mediators and NSAID effects
- Myofascial pain diagnosis and treatment
- Gout, Hyperuricemia, Uric Acid
- Bone Metabolism and Diseases
- NF-κB Signaling Pathways
- Vascular Tumors and Angiosarcomas
- Receptor Mechanisms and Signaling
- Laser Applications in Dentistry and Medicine
- Spine and Intervertebral Disc Pathology
- Orthodontics and Dentofacial Orthopedics
- Asthma and respiratory diseases
- Synthesis and Biological Evaluation
- Railway Engineering and Dynamics
- Axon Guidance and Neuronal Signaling
- Hip disorders and treatments
- Neurotransmitter Receptor Influence on Behavior
- Histone Deacetylase Inhibitors Research
Peking University
2011-2024
National Clinical Research Center for Digestive Diseases
2024
Stomatology Hospital
2014-2016
October 6 University
2016
King University
2007
University of Ottawa
2000
Abstract Objective To determine the possible involvement and regulatory mechanisms of Wnt‐5A signaling in interleukin‐1β (IL‐1β)–induced increase matrix metalloproteinase 1 (MMP‐1), MMP‐3, MMP‐9, MMP‐13 expression temporomandibular joint (TMJ) condylar chondrocytes. Methods Primary rabbit chondrocytes were treated with IL‐1β, purified protein, or both transfected vector. Expression Wnt‐5A, MMP‐1, MMP‐13, type II collagen, as well cell morphologic changes, examined. explore action...
The level of expression the 5-HT1A receptor in raphe and limbic systems is implicated etiology treatment major depression anxiety disorders. rat gene regulated by a proximal TATA-driven promoter upstream repressors that inhibit expression. Deletion 71-base pair (bp) segment between −1590/−1519 bp induced over 10-fold enhancement transcriptional activity both receptor-expressing (RN46A SN48 septal) cells receptor-negative (L6 myoblast C6 glioma) cells. A 31-bp repressor was protected from...
To evaluate the diagnostic efficacy of CBCT-MRI fused image for anterior disc displacement and bone changes temporomandibular joint (TMJ), which are main imaging manifestations disorders (TMD).Two hundred thirty-one TMJs 120 patients who were diagnosed with TMD selected study. The displacement, defect hyperplasia evaluated by three experts used as a reference standard. Three residents individually all sets images, CBCT MRI images from individual in random order above-mentioned five-point...
To present a method for image fusion of cone beam CT (CBCT)/CT and MRI to explore whether the data sets fused in such way could aid detection temporomandibular joint (TMJ) anatomical structures lesions.There were five cases included this study. One case was space occupying lesion giant cell tumour tendon sheaths, one chronic inflammation condyle, articular disc calcification bilateral TMJs, other two TMJ disorders (anterior displacement without reduction). The digital imaging communications...
Background Over 70% of the total tissue weight in cartilage matrix consists water, and early-stage osteoarthritic is characterized by swelling. Water transport across membranes chondrocytes may be important normal pathological conditions cartilage. The purpose this study was to identify aquaporin-1 (AQP1) aquaporin-3 (AQP3) expressions mandibular condylar after experimentally induced osteoarthritis (OA) rats. Methods An experimental temporomandibular joint OA partial discectomy...
Aneurysmal bone cyst (ABC) is a rare, rapidly expanding, locally destructive, and easily misdiagnosed lesion. An ABC of the condyle rare. This report presents 25-year-old female with giant in left mandibular condyle. patient was treated surgical resection affected immediate reconstruction using autologous bone. Follow-up to date showed no signs recurrence. The clinical feature, imaging finding, pathogenesis, treatment methods ABCs are discussed.
Histone deacetylase 4 (HDAC4) regulates chondrocyte hypertrophy and bone formation. The aim of the present study was to explore effects HDAC4 on Interleukin 1 beta (IL-1β)-induced extracellular matrix degradation whether it is regulated through WNT family member 3A (WNT3A)/β-catenin signaling pathway.Primary chondrocytes (CC) human chondrosarcoma cells (SW1353 cells) were treated with IL-1β level assayed using Western blotting. Then, expression in SW1353 silenced small interfering RNA detect...
Abstract The calcification of the articular disc is an uncommon lesion, usually discovered in hips, elbows, and shoulders, but rarely temporomandibular joints (TMJ). TMJ may be related to pain limitation mandibular mobility, however, most patients were asymptomatic. A 61-year-old female was referred our hospital after a maxillofacial fist injury, bilateral calcifications found accidentally by radiological examination. Here significance image fusion cone-beam computed tomography magnetic...