A5022406711- Reproductive Biology and Fertility
- Assisted Reproductive Technology and Twin Pregnancy
- Ovarian function and disorders
- Reproductive Health and Technologies
- Monoclonal and Polyclonal Antibodies Research
- Demographic Trends and Gender Preferences
- Glycosylation and Glycoproteins Research
- Protein purification and stability
- Sperm and Testicular Function
- Radiopharmaceutical Chemistry and Applications
- Reproductive Physiology in Livestock
- Prenatal Screening and Diagnostics
- Reproductive System and Pregnancy
- Family Dynamics and Relationships
- Insurance, Mortality, Demography, Risk Management
- Birth, Development, and Health
- Endometriosis Research and Treatment
- Hypothalamic control of reproductive hormones
- demographic modeling and climate adaptation
- Ovarian cancer diagnosis and treatment
- Biotin and Related Studies
- Drug Transport and Resistance Mechanisms
- Earth Systems and Cosmic Evolution
- Immune Response and Inflammation
- Salivary Gland Disorders and Functions
Odense University Hospital
2007-2023
University of Southern Denmark
2021
European Society of Human Reproduction and Embryology
2013-2017
Rigshospitalet
2006
Aarhus University Hospital
2003
The 14th European IVF—monitoring (EIM) report presents the results of medically assisted reproduction treatments including reproductive technology (ART) cycles and intrauterine insemination (IUI) initiated in Europe during 2010: are there changes trends compared with previous years? Despite some fluctuations number countries reporting, overall ART has continued to increase year by year, while pregnancy rates 2010 remained similar those reported 2009, transfers multiple embryos (three or...
Are there any changes in the treatments involving ART and IUI initiated Europe during 2013 compared with previous years?An increase overall number of cycles resulting from a higher countries reporting data was evident, pregnancy rates (PRs) remained stable those reported 2012, transfers multiple embryos (3+) lower than ever before yet delivery (DRs) unchanged, activity success were similar to last years.Since 1997, have been collected 16 manuscripts, published Human...
The 13th European in vitro fertilization (IVF)-monitoring (EIM) report presents the results of treatments involving assisted reproductive technology (ART) initiated Europe during 2009: are there any changes trends compared with previous years?Despite some fluctuations number countries reporting data, overall ART cycles has continued to increase year by and, while pregnancy rates 2009 remained similar those reported 2008, transfers multiple embryos (3+) and delivery declined.Since 1997, data...
The 16th European IVF-monitoring (EIM) report presents the data of treatments involving assisted reproductive technology (ART) and intrauterine insemination (IUI) initiated in Europe during 2012: are there any changes compared with previous years? Despite some fluctuations number countries reporting data, overall ART cycles has continued to increase year by year, pregnancy rates (PRs) 2012 remained stable those reported 2011, transfers multiple embryos (3+) delivery were lower than ever...
The 15th European IVF-monitoring (EIM) report presents the results of treatments involving assisted reproductive technology (ART) initiated in Europe during 2011: are there any changes trends compared with previous years?Despite some fluctuations number countries reporting data, while overall ART cycles has continued to increase year by year, pregnancy rates 2011 decreased slightly those reported 2010, and transfers multiple embryos (3+) delivery declined.Since 1997, data have been collected...
Does a GnRH agonist (GnRHa) trigger followed by bolus of 1.500 IU hCG in group patients at risk ovarian hyperstimulation syndrome (OHSS) reduce the OHSS incidence compared with trigger? A GnRHa early luteal support one appears to OHSS; however, low-risk second induced two cases late onset OHSS. is an alternative antagonist co-treated cycles. Two RCTs were performed four Danish IVF units. total 446 assessed for eligibility and 390 enrolled study from January 2009 until December 2011. The...
This paper reports data from the Danish in-vitro fertilization (IVF) registry 1994 to 1995 including on treatments and results of these (perinatal outcome, cytogenetic findings fetal malformations) in comparison with a control group matched for maternal age, parity, multiplicity year birth. There were 1756 deliveries 2245 children (24.3% twins, 1.8% triplets). The rate prematurity among IVF was 23.8% (NS) [singletons 7.3% (P < 0.05), twins 41.2% triplets 93.5%], 23.6% weighed <2500 g 7%...
Is the chance of a live birth following IVF treatment and fresh embryo transfer affected by early mid-luteal serum progesterone (P4) levels?Low as well high P4 levels in phase reduce with transfer.Data from non-human studies frozen-thawed cycles indicate that low during decrease pregnancy. The altered pattern may disrupt endometrial maturation leading to asynchrony between embryonic development receptivity, thereby, compromising implantation pregnancy.Prospective multicenter cohort study 602...
This national cohort study included all clinical pregnancies obtained after intracytoplasmic sperm injection (ICSI) registered in Denmark between January 1994 and July 1997 at five public eight private fertility clinics. Laboratory data were from the The couples answered a questionnaire regarding pregnancy health of child (response rate 94%). Data validation was carried out through discharge charts. mean age women 32.1 years. In 84.2% couples, male factor main reason for performing ICSI,...
The role of LH in sensitizing antral follicles to FSH is unclear. required for normal hormone production and oocyte embryo development, but follicular responses may depend upon the stage development. Potential roles at early phase were explored a clinical setting by employing sequential approach stimulation recombinant human (r-h) followed r-hFSH women who profoundly down-regulated depo GnRH agonist. We employed multi-centre, prospective, randomized approach. Women (n = 146) treated long...
Follow-up studies of children conceived after ICSI using epididymal or testicular sperm are important due to a still more extensive use immature male germ cells for ICSI. It is, however, difficult evaluate the potential risks malformations born ICSI, overcoming natural fertilization processes, methodological limitations. study including all in Denmark and Norway following Denmark, sperm, was done. A questionnaire sent parents between 3 months 7 years delivery. Of 341 couples, 329 returned...
It has been suggested that the luteinizing hormone (LH) activity of human menopausal gonadotrophin (HMG) preparations used for ovarian stimulation in in-vitro fertilization (IVF) may have adverse effects on reproductive outcome. In present prospective, randomized trial 218 infertile couples this notion was investigated. A total 114 women were treated with Pergonal (HMG group) and 104 Fertinorm HP (HP-FSH group). The two groups comparable regard to duration infertility, cause age number...
Subject. Data from the compulsory Danish National IVF Registry 1994 and 1995 regarding treatments, abortions complications following assisted reproductive technologies. Methods. were generated through registries compared to pregnancies in Denmark 1995. Those that resulted a delivery matched control group. Results. In 5219 women treated 9471 initiated cycles. The numbers increased over period. overall rate per cycle was 19%, egg donation 24%, 20%, ICSI 16% frozen replacement 10%. rates of...
The aim of the study was to analyse trends in rate natural conceptions (RNC) among birth cohorts women born during period 1960–1984. In this nationwide Danish-born female 1960–1984, we found a gradual decline RNC with successive cohorts. Our results confirm findings from previous on native Danish women. This is register-based cohort study. data set included 803 435 whom 68.2% had conceived at least one child as 1 January 2008, by which time follow-up terminated. Data national registers were...
Abstract Human‐human hybridoma technology was evaluated for the study of humoral immune reactions colorectal cancer patients against their own tumors. Six fusions were carried out with lymphocytes from mesenteric lymph nodes cancer, using human B‐lymphoma cell line LICR‐LON‐HMy‐2 as fusion partner. A total 294 wells growth obtained. Supernatants 26 these reacted in enzyme‐linked immuno‐sorbent assay (ELISA) one or more colon lines. Cells only (D 4213) could be cloned. The clone shown to...
Endogenous immunoglobulin in tissue sections pose a problem immuno-histochemical techniques employing homologous antibody as primary reagents and enzyme-labelled anti-immunoglobulin for the development. A method blocking of endogenous human by incubation with monomeric pepsin fragments (Fab') rabbit anti-human before applying monoclonal was evaluated screening antibody. It initially demonstrated that Fab' IgM anti-IgG could block IgG producing tumors thereby abolishing binding subsequently...
Abstract Objective To examine the costs to public health care system of couples in medically assisted reproduction. Design Longitudinal cohort study infertile initiating reproduction treatment. Setting Specialized fertility clinics Denmark. Sample Seven hundred and thirty‐nine having no child at entry with data on kind treatment live birth (yes/no) for each attempt specialized clinic. Methods Treatment attempts conducted were abstracted from medical records. Flow diagrams drawn different...