- Reproductive System and Pregnancy
- Ovarian function and disorders
- Endometriosis Research and Treatment
- Reproductive Physiology in Livestock
- Gynecological conditions and treatments
- Assisted Reproductive Technology and Twin Pregnancy
- Ectopic Pregnancy Diagnosis and Management
- Reproductive Health and Technologies
- Reproductive Biology and Fertility
- Pelvic floor disorders treatments
- Ovarian cancer diagnosis and treatment
- Pregnancy and preeclampsia studies
- Ureteral procedures and complications
- Intestinal and Peritoneal Adhesions
- Neonatal Respiratory Health Research
- Male Reproductive Health Studies
- Congenital gastrointestinal and neural anomalies
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Appendicitis Diagnosis and Management
- Clinical Laboratory Practices and Quality Control
- Anesthesia and Pain Management
- Prenatal Substance Exposure Effects
- Nausea and vomiting management
- Spine and Intervertebral Disc Pathology
- Preterm Birth and Chorioamnionitis
University of Copenhagen
1996-2020
Roskilde Sygehus
2008-2020
Zealand University Hospital
2017-2020
Zealand University Hospital Køge
2019-2020
Copenhagen University Hospital
1996-2014
Rigshospitalet
1993-2011
Herlev Hospital
1993-2008
Hvidovre Hospital
2008
Glostrup Hospital
1993
Dansk Sygehus Institut
1993
Many retrospective studies have shown that hydrosalpinx is associated with poor in-vitro fertilization (IVF) outcome. The mechanism of the actual cause not yet fully understood. A clinical practice performing salpingectomy before IVF has developed, without any evidence from prospective trials. aim present randomized trial was to test if a prior effective in terms increased pregnancy rates. Patients were either laparoscopic or no intervention IVF. total 204 patients available for an...
BACKGROUND: The aim was to identify independent predictors of ovarian response recombinant (r)FSH through a multiple regression analysis. METHODS: Prospective study including 145 ‘standard’ patients treated with 150 IU/day rFSH during their first IVF/ICSI cycle. Down‐regulation achieved long agonist protocol. following were examined as possible predictive factors: age, body mass index, cycle length, smoking status and on day 2–5: total volume, number antral follicles (<10 mm), Doppler score...
Abstract: To determine if a 14‐bp deletion/insertion polymorphism in the 3′‐untranslated region of exon 8 gene encoding human leukocyte antigen (HLA)‐G homozygous form is associated with repeated, unsuccessful vitro fertilization (IVF) treatments, and increased risk recurrent spontaneous abortions (RSA), 29 white women undergoing IVF 61 RSA 93 fertile controls were HLA‐G genotype. The genotype, for presence 14 bp sequence 8, was significantly reduced fertility respect to treatments...
BACKGROUND: A randomized controlled trial of salpingectomy prior to IVF in patients with hydrosalpinges has been conducted Scandinavia. The results from the first transfer cycle have published and clearly demonstrated an improved pregnancy outcome after had performed large enough be visible on ultrasound. present article is aimed at analysing effect cumulative birth rate, including all individual cycles. METHODS AND RESULTS: total 186 women underwent 452 Among 77 no surgical intervention, 24...
A hundred patients scheduled for elective abdominal surgery were randomized to either general anaesthesia (low‐dose fentanyl) and systemic morphine postoperative pain or combined epidural analgesia with etidocaine 1.5% intraoperatively (T 4 ‐S 5 ) bupivacaine 0.5% ml/4 h 24 mg/12 72 h. Postoperative was better controlled by the regimen ( P <0.0001). We found no significant reduction in mortality (6% 2%), pneumonia (28% 20%), cardiac dysrhythmia (10% 5%) wound complications (14% 11%)...
This national cohort study included all clinical pregnancies obtained after intracytoplasmic sperm injection (ICSI) registered in Denmark between January 1994 and July 1997 at five public eight private fertility clinics. Laboratory data were from the The couples answered a questionnaire regarding pregnancy health of child (response rate 94%). Data validation was carried out through discharge charts. mean age women 32.1 years. In 84.2% couples, male factor main reason for performing ICSI,...
Summary. A total of 1639 women attending the antenatal clinic Gentofte University Hospital, Copenhagen, during 1986–1987 was randomized into a symphyseal fundal (SF)‐group and control group. The in SF‐group had their height measured from 29th week until delivery. measurements were used along with other usual screening procedures. SF‐measurements not found helpful prediction small‐for‐gestational‐age infants no significant differences between two groups regarding number interventions,...
One of the non-classical human leukocyte antigen (HLA) class Ib proteins, HLA-G, is believed to exert important immunoregulatory functions, especially during pregnancy. The presence HLA protein in paternal seminal fluid has been suggested have an influence on risk developing pre-eclampsia. We investigated whether HLA-G present plasma and different tissue samples male reproductive system. Western blot technique a soluble (sHLA-G) assay were used detect sHLA-G samples. Immunohistochemical...
To investigate the consequence of salpingectomy on ovarian reserve by measuring anti-Müllerian hormone (AMH) levels before in vitro fertilization (IVF) treatment salpingectomized women compared with nonsalpingectomized tubal factor infertility, unexplained infertility and fertile control women, to evaluate whether AMH could predict IVF outcome.Cross-sectional study extended from a previous prospective study.Four university fertility clinics.Seventy-one 21 controls.Blood sampling embryo...
Problem Elucidating immune mechanisms in the endometrium, which lead to success of implantation and pregnancy, is important reproductive medicine. Studies cell abundance have shown conflicting results, expression importance HLA class Ib proteins pre‐implantation endometrium not yet been investigated. Method study The population consisted four subgroups: a hydrosalpinx, salpingectomy, an unexplained infertility, fertile control group. Endometrial samples were collected during window. Immune...
Problem We have previously shown that human seminal plasma contains immunomodulatory soluble HLA-G (sHLA-G). investigated whether sHLA-G levels in are associated with a specific 14 base pair (bp) insertion/deletion (ins/del) polymorphism the 3′-untranslated region of gene and/or outcome assisted reproduction treatments (ART) couples attending fertility clinic. Method Study In total 54 unselected couples, were measured samples and blood samples, genotyping was performed, clinical data...
The aim of this study was to investigate a possible influence three single nucleotide polymorphisms (SNPs) in the HLA-F gene locus on time-to-pregnancy and pregnancy success after fertility treatment.HLA-F SNP genotypes diplotypes are associated with number treatment cycles needed achieve live birth.HLA class Ib molecules, including HLA-F, which known be expressed by extra-villous trophoblast cells have immunomodulatory properties play role at feto-maternal interface. However, few recent...
BACKGROUND: In patients with ultrasound-visible hydrosalpinges, salpingectomy prior to IVF increases the chance of a live birth. This study compared cost-effectiveness this strategy (intervention) that optional after failed cycle (control). METHODS: Data from Scandinavian randomized controlled trial were used calculate individual number treatments and their outcomes. Only hydrosalpinges considered in main analysis, maximum three fresh cycles included. The costs for surgical procedures,...