We studied clinical outcomes of COVID-19 infection in patients living with HIV (PLH) comparison to non-HIV population.Analysis a multicentre research network TriNETX was performed including more than 10 years age diagnosed COVID-19.Outcomes positive concurrent were compared propensity-matched cohort without (non-PLH).Fifty thousand one hundred and sixty-seven identified (49,763 non-PLH, 404 PLH). PLH likely be men, African-American, obese have hypertension, diabetes, chronic kidney disease...

Background. Organ transplant recipients comprise an immunocompromised and vulnerable cohort. Outcomes of coronavirus disease 2019 (COVID-19) in solid organ (SOT) remain understudied. Methods. We used a multicenter federated research network to compare clinical outcomes COVID-19 patients with SOT propensity--matched cohort without SOT. Results. identified 2307 231 047 nontransplant COVID-19. Transplant were more likely be male individuals, older, have body mass index >30 kg/m 2 , comorbid...

Introduction Outcomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in patients with pre-existing idiopathic pulmonary fibrosis (IPF) remain understudied, and it is unknown if IPF an independent predictor worse disease course. Herein, we report the clinical outcomes a large cohort 251 COVID-19 setting known IPF. were compared propensity matched without Methods Analysis federated multicentre research network TriNetX was performed including more than 16 years age...

Recurrent Graves' disease due to regrowth of thyroid tissue is a rare complication near-total thyroidectomy, which can be challenging recognize and manage. Here, we present the case 30-year-old woman with eye who underwent thyroidectomy resultant hypothyroidism. Her levothyroxine dose requirement gradually decreased thyroglobulin level increased, led diagnosis recurrent disease. A neck ultrasound showed tissue. The treatment options in such cases are repeat surgery radioactive iodine...

INTRODUCTION Management of malignant colorectal polyps is controversial. The options are resection or surveillance. Resection margin status accepted as an independent predictor adverse outcome. However, the rate outcome in with a <1mm has not been investigated. METHODS A retrospective search pathology database was undertaken. All polyp cancers were included. single histopathologist reviewed all included cancers. Polyps divided into three groups: clear margin, involved and unknown margin....

Abstract Background and Aim Current guidelines suggest screening at‐risk groups of patients for Barrett's esophagus (BE), a precursor to esophageal cancer. Although BE obstructive sleep apnea (OSA) have common risk factors, including elevated body mass index gastroesophageal reflux disease (GERD), the relationship between these two conditions has not been well established. Methods Retrospectively, all who had undergone polysomnography esophagogastroduodenoscopy at West Virginia University...

Abstract Background One of the most feared complications endoscopic retrograde cholangiopancreatography (ERCP), with an incidence 3.5 to 15%, is post ERCP pancreatitis (PEP). Given role statins in reduction systemic and pancreatic intraluminal inflammation, we hypothesized that use may lower risk PEP. Methods A retrospective cohort study all patients undergoing at West Virginia University during years 2016 2017 was performed. Possible association collected variables PEP assessed Univariate...

<b><i>Introduction:</i></b> Protracted exposures to small doses of radiation, even cumulative effective (CED) as low 50–100 mSv, may increase the risk for malignancy. Medical radiation exposure has not been rigorously examined patients with irritable bowel syndrome (IBS). We medical in IBS at a tertiary care center USA. <b><i>Methods:</i></b> Patients diagnosed our institute from 2009 2018 were included retrospective cohort study. charts...

We studied the safety and efficacy of warfarin compared to direct acting oral anticoagulant use in patients with IPF.We conducted a retrospective cohort study all IPF who were prescribed or anticoagulants (DOACs) for cardiac thromboembolic indications followed at our institute their care. Univariate tests multivariable logistic regression analyses used assessing association variables outcomes.A total 73 included 28 45 DOAC groups, respectively. Univariable analysis revealed significant...

Introduction Breast cancer is considered the most common malignant tumor in women, and incidence rates have risen progressively over last decades. Modified radical mastectomy (MRM) an effective treatment option. This research sought to establish frequency, causes, distribution of postoperative complications that are associated with MRM Pakistani population suffering from breast cancer. Materials methods A descriptive cross-sectional study was conducted one year (May 2023 April 2024) at...

Ischemic colitis and proctitis is a rare manifestation of systemic lupus erythematosus (SLE) results from mesenteric vasculitis. Owing to diverse blood supply presence multiple collaterals, rectum the least effected site in SLE enteritis. proctocolitis as presenting feature exceedingly rare, with only three cases reported published scientific literature. We present first case ischemic proctitis, leading intraperitoneal hemorrhage abdominal compartment syndrome. A young lady presented...

INTRODUCTION: Current guidelines suggest screening at-risk groups of patients for Barrett's esophagus (BE), a precursor to esophageal cancer. Although BE and obstructive sleep apnea (OSA) have common risk factors, including elevated body mass index (BMI) gastroesophageal reflux disease (GERD), the relationship between these two conditions has not been well established. METHODS: Retrospectively, all who had undergone polysomnography esophagogastroduodenoscopy (EGD) at West Virginia University...

Critical Care Medicine: January 2021 - Volume 49 Issue 1 p 490 doi: 10.1097/01.ccm.0000729828.56129.4d

INTRODUCTION: Direct acting oral anticoagulants (DOACs) are increasingly used for various indications, however their use in patients with cirrhosis is unclear. These agents currently not approved Child class C cirrhosis, due to exclusion from clinical trials and very limited data. METHODS: We performed a retrospective cohort study of all who were prescribed at our tertiary care university hospital 2010 2018. Clinical outcomes between DOAC warfarin prescriptions compared. Log-Rank tests...

Abstract We present a case of 30-year-old female with past medical history Type 2 DM, Thyroid nodule and asymptomatic cholelithiasis who presented to ED abdominal pain, vomiting sinus tachycardia 120’s for one day. She had generalized not relieved by pain killers. Her lab test includes normal blood count, glucose 150mg/dl, anion gap 20, metabolic acidosis. ultrasound abdomen showed no biliary sludge formation. Given her acidosis severe she was started on Zosyn underwent cholecystectomy. did...

Introduction: Cirrhosis is associated with high mortality in COVID-19. Although COVID-19 vaccines are now available and being administered to the public, their safety efficacy patients cirrhosis have not been studied. We aimed study of Pfizer-BioNTech Moderna mRNA compared without cirrhosis. Methods: performed a retrospective cohort utilizing TriNetx multi-institutional research network analyze who received vaccines. Outcomes were between diagnosis non-cirrhosis groups also using 1:1...