A5020087986- Diabetes, Cardiovascular Risks, and Lipoproteins
- Lipoproteins and Cardiovascular Health
- Obstructive Sleep Apnea Research
- Health and Lifestyle Studies
- Adipokines, Inflammation, and Metabolic Diseases
- Respiratory Support and Mechanisms
- Tracheal and airway disorders
- Cardiovascular Disease and Adiposity
- Sleep and related disorders
- Global Public Health Policies and Epidemiology
- Foreign Body Medical Cases
- Autoimmune and Inflammatory Disorders
- Blood Pressure and Hypertension Studies
- Liver Disease Diagnosis and Treatment
- Research on Leishmaniasis Studies
- Diabetes Treatment and Management
- Cardiovascular Function and Risk Factors
- IgG4-Related and Inflammatory Diseases
- Cardiac Imaging and Diagnostics
- Autoimmune Bullous Skin Diseases
- Fungal Infections and Studies
- Cardiovascular Health and Disease Prevention
- Pneumothorax, Barotrauma, Emphysema
- Cancer, Lipids, and Metabolism
- COVID-19 and healthcare impacts
West Virginia University
2020-2025
West Virginia University Hospitals
2024
University of Virginia
2020-2022
University of Virginia Health System
2022
Rütgers (Germany)
2020
Rutgers, The State University of New Jersey
2016-2020
Rutgers Sexual and Reproductive Health and Rights
2018-2020
Rutgers New Jersey Medical School
2016-2020
University of Virginia Hospital
2020
Cleveland Clinic Florida
2018-2019
Infection by helminthic parasites can cause the polyclonal stimulation of IgE synthesis, possibly via an enhanced production interleukin-4 (IL-4), and this has been suggested to influence allergic reactivity tropical populations where these are endemic. We evaluated a group urban slum children in Caracas, Venezuela, with high prevalence infection (70.8%), establish relationship between elevated levels (3696 IU/ml) induced various aspects response. Although absolute IL-4 detected sera were...
Adipose tissue accumulation in specific body compartments has been associated with diabetes, hypertension and dyslipidemia. Perirenal fat (PRF) may lead to have direct lipotoxic effects on renal function intrarenal hydrostatic pressure. This study was undertaken explore the association of PRF cardiovascular risk factors different stages chronic kidney disease (CKD).We studied 103 patients CKD (1 5). measured by B-mode ultrasonography distal third between cortex hepatic border and/or...
SUMMARY Total and Ascaris-specific serum IgE levels were measured in a group of 98 Ascaris-infected children from slum area Caracas. Venezuela, whom the infections eliminated by regular treatment for 22 months with anthelmint Oxantel/ Pyrantel (‘Quanlrel’). The re-evalualed at end programme, then 8 later, which time reinfection was assessed. beginning study significantly higher who became reinfected after treatment. compared those did not. caused significant decrease tolal most children,...
Abstract Introduction Sleep is a key component of healthy lifestyle and the Center for Disease Control (CDC) prevention recommends that adults get at least 7 hours sleep each night. Within United States, West Virginia among most sleep‐deprived states with 42% population reporting insufficient per CDC. insufficiency in rural populations linked to disparities health accessibility care services. The study evaluated impact hygiene (SH) education on duration quality. Methods A 12‐week randomized...
Rationale Patients with acute-on-chronic hypercapnic respiratory failure suffer from recurrent readmissions due to acute exacerbations. These patients carry higher readmission and mortality rates compared the general population. Objectives We aimed delineate outcomes of discharged on non-invasive ventilation. Methods A cross-sectional study was conducted. One hundred nine were evaluated qualified for ventilation at discharge. Adherence data collected post-discharge following evaluated:...
The metabolic syndrome (MS) is a conglomerate of interrelated risk factors-including obesity, atherogenic dyslipidemia, arterial hypertension, and insulin resistance-which exponentially increase the developing cardiovascular disease type 2 diabetes mellitus. purpose this study was to determine prevalence MS according criteria published by International Diabetes Federation, in individuals both sexes over 18 years age. This cross-sectional based on representative sample from Maracaibo...
By using a PCR assay specific for Leishmania braziliensis in blood samples, we detected this parasite patients cured by immunotherapy or at different stages of treatment. We also found the subjects who had never suffered leishmaniasis but lived endemic areas and migrated to nonendemic ones many years ago. These results suggest that L. infections are difficult eradicate clinical cure rarely complete elimination is generally accomplished.
<ns4:p>The direct link between lipid metabolism alterations and the increase of cardiovascular risk are well documented. Dyslipidemias, including isolated high LDL-c or mixed dyslipidemia, such as those seen in diabetes (hypertriglyceridemia, low HDL-c), correlate with a significant cerebrovascular disease worldwide. This review analyzes current knowledge concerning genetic basis alterations, emphasizing lipoprotein lipase gene mutations HindIII polymorphism, which associated decreased...
Obstructive sleep apnea (OSA) is a highly prevalent, yet underdiagnosed, condition. Due to its adverse impact on risk for cardiopulmonary disorders, there interest in proactive screening of OSA hospitalized patients. We studied the long-term outcome such screened patients who were initiated positive airway pressure therapy.
Journal Article Relationship between the degree of poverty and IgE response to Ascaris infection in slum children Get access Isabel Hagel, Hagel 1Institute Biomedicine, Faculty Medicine, Central University Venezuela, Caracas, Venezuela Search for other works by this author on: Oxford Academic PubMed Google Scholar Neil R. Lynch, Lynch ∗ ∗Address correspondence: Dr Instituto de Biomedicina, Aptdo 4043, 1010A, Venezuela. Mireya Pérez, Pérez 2J. M. los Rios Children's Hospital, Maria C. Di...
<ns4:p>The direct link between lipid metabolism alterations and the increase of cardiovascular risk are well documented. Dyslipidemias, including isolated high LDL-c or mixed dyslipidemia, such as those seen in diabetes (hypertriglyceridemia, low HDL-c), correlate with a significant cerebrovascular disease worldwide. This review analyzes current knowledge concerning genetic basis alterations, emphasizing lipoprotein lipase gene mutations HindIII polymorphism, which associated decreased...
The Go Red for Women (GoRedW) campaign aims to increase awareness of cardiovascular disease (CVD) and stroke in women. However, assessing the effects social campaigns on information-seeking behaviors may be challenging. purpose this study was ascertain effect GoRedW using a large sample unbiased real-world data from Google Trends (GTr) evaluate temporal correlation online search queries CVD women with GoRedW.We conducted retrospective GTr, public tool engine obtain relative volumes (RSVs)...
To assess 30-day mortality in coronavirus disease 2019 acute respiratory distress syndrome patients transferred from rural Appalachian hospitals.Retrospective case controlled, based on consecutive and admitted hospitals to a tertiary-care ICU. The primary outcome was all-cause mortality. Kaplan-Meier method log-rank test were used the survival data analysis.Medical ICU, West Virginia University Hospital, Morgantown, WV.All adult ICU for between September 30, 2020, December 2, 2020.Not...
The beginnings of the Metabolic Syndrome (MetS) as a suspected, not yet recognized entity can be traced back to 1923 when study concerning particularly common clustering metabolic entities observed in diabetic patients was first published. Years research and endless debate yielded currently accepted MetS definition diagnostic criteria, even if some components their cut-off points are still up for discussion. To date, defined risk factors that greatly increase incidence cardiovascular disease...
In order to determine whether infection by helminthic parasites can be associated with a state of bronchoconstriction, we evaluated the response inhalation bronchodilator before and after long-term antihelminthic treatment children in urban slum Caracas, Venezuela. untreated children, direct association was found between degree increase peak expiratory flow rates caused bronchodilator. The elimination infections accompanied significant decrease These results indicate that could contribute...
Bronchiectasis is a well-known entity where the airways abnormally dilate losing their natural function. Most common causes of non-cytic fibrosis bronchiectasis in middle age group include secondary immunodeficiency, aspiration, and allergic bronchopulmonary aspergillosis (ABPA). Obstructive foreign body an uncommon cause often missed diagnosis localized disease. Foreign bodies can be making treatment more challenging hence should considered patients presenting with focal Here we describe...
The prevalence of type 2 diabetes mellitus has increased at an alarming rate in recent years. Recent estimations project that 366 million people could have by 2030. incretin system emerges as a new target for therapy, and molecules are being approved its use humans since the year 2005. These agents be divided into main groups, glucagon-like peptide-1 (GLP-1) receptor agonists dipeptidyl peptidase-4 inhibitors. Endogenous GLP-1 is hormone composed 30-amino acid peptide secreted from L-cells...