A5005790254- Hemoglobinopathies and Related Disorders
- Iron Metabolism and Disorders
- Blood donation and transfusion practices
- Prenatal Screening and Diagnostics
- Maternal and fetal healthcare
- Blood groups and transfusion
- Pregnancy and preeclampsia studies
- Maternal and Perinatal Health Interventions
- Child Nutrition and Water Access
- Hepatitis B Virus Studies
- Neonatal Health and Biochemistry
- Forensic and Genetic Research
- Clinical practice guidelines implementation
- Clinical Laboratory Practices and Quality Control
- Pregnancy-related medical research
- Colorectal Cancer Screening and Detection
- Cardiac, Anesthesia and Surgical Outcomes
- Dialysis and Renal Disease Management
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Berberine and alkaloids research
- Parvovirus B19 Infection Studies
- Complement system in diseases
- Poverty, Education, and Child Welfare
- Veterinary Pharmacology and Anesthesia
- Phytochemistry Medicinal Plant Applications
University of Lagos
2015-2024
Bowen University
2024
Lagos University Teaching Hospital
2024
Apollo Hospitals
2024
Creative Commons
2023
Federal Medical Centre
2023
Babcock University
2023
Ladoke Akintola University of Technology
2022
McMaster University
2022
Medical College of Wisconsin
2022
Abstract Background Most previous clinical studies investigating the connection between prenatal anaemia and postpartum haemorrhage (PPH) have reported conflicting results. Objectives We examined association maternal risk of PPH in a large cohort healthy pregnant women five health institutions Lagos, Southwest Nigeria. Methods This was prospective analysis data from Predict-PPH study that conducted January June 2023. The enrolled n = 1222 giving birth hospitals outcome, WHO-defined PPH, is...
Tuberculosis (TB), an infectious disease caused by Mycobacterium tuberculosis is still one of the leading public health problems, despite advances in effort to reduce its incidence, morbidity, and mortality. Studies have shown that prevalence depression correlated with severity duration tuberculosis. Therefore this study aims find out pattern among drug-susceptible TB patients improve treatment outcomes thereby morbidity mortality from disease. The was a cross-sectional hospital-based...
BACKGROUND: Tuberculosis (TB), an infectious disease caused by _Mycobacterium tuberculosis_ is still one of the leading public health problems, despite advances in effort to reduce its incidence, morbidity, and mortality. Studies have shown that prevalence depression correlated with severity duration tuberculosis. Therefore this study aims find out pattern among drug-susceptible TB patients improve treatment outcomes thereby morbidity mortality from disease. METHODOLOGY: The was a...
Background . ABO hemolytic disease of the newborn is most common consequence maternofetal blood group incompatibility restricted mostly to non-group-O babies O mothers with immune anti-A or anti-B antibodies. Aim We estimated risk HDN view determining need for routine screening between mother and fetus. Materials Methods Prevalence phenotypes in donors at donor clinic Lagos University Teaching Hospital arithmetic methods were used determine population prevalence genes. then proportion...
Request forms are important means of communication between physicians and diagnostic service providers. Pre-analytical errors account for over two thirds encountered in provision. The importance adequate completion request is usually underestimated by which may result medical or delay instituting appropriate treatment. aim this study was to audit the level presented at a multidisciplinary center.A review all requests investigations included radiologic, laboratory cardiac received July...
Background: The magnitude and risk factors for postpartum haemorrhage (PPH) have been extensively investigated, although little is currently known about the incidence predictors of severe PPH, specifically among women affected by prenatal anaemia in Nigeria. Objectives: study determined antepartum PPH anaemic pregnant five health institutions Lagos, Southwest Methods: A secondary analysis was performed using data with from "Predict-PPH" that conducted between January June 2023. This included...
Group O donor blood is more readily available and frequently used as universal red cell in our environment. The presence of hemolysins the donors may however lead to hemolysis recipients. Attempts have been made study prevalence various populations with results from environment showing wide variation (20-80%).To determine titer anti-A anti B among at Lagos University Teaching Hospital compare that obtained elsewhere. Determine if practice transfusion group nongroup recipients permissible...
sickle cell disease (SCD) refers to a group of inherited blood disorders that are life-long and affect many people globally. An estimate 2.3% the Nigerian population suffer from SCD about 25% adults have gene. Premarital screening for gene is considered one methods preventing new births children with among young adults. The study assessed knowledge, attitude, willingness take premarital test factors influencing knowledge unmarried in an urban community Lagos, Nigeria.the was cross-sectional...
Background: Haematopoietic stem cell transplantation (HSCT) is a potentially curative treatment for sickle anaemia (SCA). While HSCT offers the possibility of disease remission, it can also lead to long-term complications, including gonadal dysfunction and premature menopause. Methods: We conducted retrospective cohort study female survivors who had hydroxyurea therapy those underwent post-HSCT follow-up SCA at teaching hospital in Lagos, Nigeria, between January 2019 December 2022....
Abstract The high burden of anaemia during pregnancy underscores the urgent need to gain a comprehensive understanding factors contributing its widespread occurrence. Our study assessed prevalence and trends moderate-to-severe (MSA) in late (28 36 weeks) then investigated key determinants driving this among women Lagos, Nigeria. We conducted secondary data analysis involving 1216 enrolled Predict-PPH between January March 2023. employed multivariate binary logistic regression model with...
Colorectal polyps are known precursors of colorectal cancers. The increase in utilization colonoscopy Nigeria has meant a rise the recently reported incidence these lesions. aim this study is to evaluate clinicopathological profile biopsied during inaugural 12 month period from private endoscopy suite Nigeria.This retrospective review all clients who had diagnosed at over (August 2014 -July 2015) Lagos, Nigeria. This analysis prospectively collected data was performed using clinical...
This study explores contraceptive use among young adult male and female students (aged 18-25) who visit the campus clinic at a university in KwaZulu-Natal. Both descriptive survey face to interviews were used for data collection. In this study, it is affirmed that gender stratification, societal attitudes, misconceptions about play an important role attitudes of adults, towards contraception its use. Evidence high condoms amongst both students’ compared with other available methods. Among...
The outcome of acute myeloid leukaemia (AML) has remained a major concern even in developed countries.In resource poor countries, it is envisaged that the will be far worse because late presentations, lack appropriate diagnostic facilities and supportive care.However, data to validate this lacking many these countries an effective cancer registry.This study determined clinician's perspective care AML patients Nigeria their attitudes patients.Structured self-administered questionnaire was...
Background: Rh (Rhesus) blood group antigen especially D plays a pivotal role in provision of safe and pregnancy.Antigen mismatch between donor recipient or pregnant woman the foetus sets stage for immunohaematological complication such as haemolytic transfusion reaction disease newborn.Individual knowledge status among females reproductive age is contributory measure effective control prevention untoward complications mismatch.Objective: This study assessed level awareness own female...
Abstract Background Most previous clinical studies investigating the connection between prenatal anaemia and postpartum haemorrhage (PPH) have reported conflicting results. Objectives We examined association maternal risk of PPH in a large cohort healthy pregnant women five health institutions Lagos, Southwest Nigeria. Methods This was prospective analysis data from Predict-PPH study that conducted January June 2023. The enrolled n = 1222 giving birth hospitals outcome, WHO-defined PPH, is...
Abstract Background: The magnitude and risk factors for postpartum haemorrhage (PPH) have been extensively investigated, although little is currently known about the incidence predictors of severe PPH, specifically among women affected by prenatal anaemia in Nigeria. Objectives: We determined antepartum PPH anaemic pregnant five health institutions Lagos, Southwest Methods: performed a secondary analysis data with from " Predict-PPH study conducted between January June 2023. This included...
Background: Plant products treat many diseases and are an important resource for pharmaceutical companies developing new medicines. Hemostasis maintains blood in the fluid state prevents its loss from damaged vessels. Plants have been reported to be sources of anticoagulant antithrombotic substances employed management coagulation disorders. Aim: This study investigates effects aqueous ethanolic extracts bitter leaves, mango drumstick pineapples tomatoes on vitro activity. Methods: Aqueous...
Background: Blood transfusion therapy remains a mainstay in the care of many tropical diseases. supply sub-Saharan Africa (SSA) including Nigeria is still challenge terms perennial blood shortages and transmissible infections (TTI). This study aimed to describe donation patterns compare rates TTIs among types donors seen at LUTH.
 Study method: A 6-year retrospective review data on donor pattern LUTH service. TTI odd ratios (OR) positivity amongst VNRD versus FRD were computed 95%...
BACKGROUND The aim of the study was to compare prevalence haematologic abnormalities seen in incident haemodialysis patients using standard laboratory reference ranges with derived locally. STUDY DESIGN AND METHODS This a retrospective 97 renal failure who received at single dialysis unit Lagos, Nigeria. All were 18 years age or older, had requiring dialysis, and not previously dialyzed. Patients history haemoglobinoapthy other red cell disorders, recent overt blood loss transfusion...
Context: Regular blood donations can engender iron depletion and its complications; reducing the prevalence of among donors is a key strategy for optimizing donors' health. However, factors impacting on deficiency are not yet well characterized in our environment. Aim: The aim this study to determine predonation status hematological profile donors. Settings Design: We conducted comparative cross-sectional eligible at Lagos University Teaching Hospital. Consenting participants were...
Cheap methodologies are being utilized by low-resource countries to determine blood donors' fitness. Important hematological biomarkers might have be evaluated enhance the use of these methods.The study pattern serum ferritin in 18-24 fit and unfit prospective donors (PDBs) prevalence iron store deficiency.This was a cross-sectional, comparative which conducted at donor clinic Lagos University Teaching Hospital.Blood samples were collected venipuncture into sodium-ethylenediaminetetraacetic...