Christophe Blockeel

ORCID: 0000-0001-7129-5158
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About
Contact & Profiles
Research Areas
  • Reproductive Biology and Fertility
  • Ovarian function and disorders
  • Assisted Reproductive Technology and Twin Pregnancy
  • Reproductive Health and Technologies
  • Reproductive System and Pregnancy
  • Ectopic Pregnancy Diagnosis and Management
  • Endometriosis Research and Treatment
  • Prenatal Screening and Diagnostics
  • Gynecological conditions and treatments
  • Ovarian cancer diagnosis and treatment
  • Birth, Development, and Health
  • Reproductive Health and Contraception
  • Sperm and Testicular Function
  • Pelvic floor disorders treatments
  • Sexual Differentiation and Disorders
  • Hormonal and reproductive studies
  • Reproductive tract infections research
  • Uterine Myomas and Treatments
  • Reproductive Physiology in Livestock
  • Metabolism and Genetic Disorders
  • Gut microbiota and health
  • Pregnancy and preeclampsia studies
  • Neuroendocrine regulation and behavior
  • Renal and related cancers
  • Mitochondrial Function and Pathology

Universitair Ziekenhuis Brussel
2016-2025

University of Zagreb
2016-2025

Vrije Universiteit Brussel
2015-2024

Mathys (Netherlands)
2024

RELX Group (United States)
2022

Ospedale Policlinico San Martino
2018

Hospital de Santa Maria
2018

Fertility Medical Group
2011

Monash IVF
2011

Monash University
2011

STUDY QUESTIONWhat is the impact of ovarian response on cumulative live birth rates (LBR) following utilization all fresh and frozen embryos in women undergoing their first stimulation cycle, planned to undergo single embryo transfer (SET).

10.1093/humrep/dev316 article EN Human Reproduction 2016-01-02

STUDY QUESTIONWhat is the effect of natural cycle IVF in women with poor ovarian response according to new ESHRE definition for responders: Bologna criteria?

10.1093/humrep/des318 article EN Human Reproduction 2012-08-30

Abstract The prolonged lockdown of health services providing high-complexity fertility treatments –as currently recommended by many reproductive medicine entities– is detrimental for society as a whole, and infertility patients in particular. Globally, approximately 0.3% all infants born every year are conceived using assisted technology (ART) treatments. By contrast, the total number COVID-19 deaths reported so far represents 1.0% expected to occur worldwide over first three months current...

10.1186/s12958-020-00605-z article EN cc-by Reproductive Biology and Endocrinology 2020-05-13

Is oral dydrogesterone 30 mg daily non-inferior to 8% micronized vaginal progesterone (MVP) gel 90 for luteal phase support in IVF? Oral demonstrated non-inferiority MVP the presence of fetal heartbeats at 12 weeks gestation (non-inferiority margin 10%). The standard care IVF is use MVP; however, it associated with irritation, discharge and poor patient compliance. may replace as if found be efficacious an acceptable safety profile. Lotus II was a randomized, open-label, multicenter, Phase...

10.1093/humrep/dey306 article EN cc-by-nc-nd Human Reproduction 2018-09-24

Abstract Artificial intelligence (AI)-driven language models have the potential to serve as an educational tool, facilitate clinical decision-making, and support research academic writing. The benefits of their use are yet be evaluated concerns been raised regarding accuracy, transparency, ethical implications using this AI technology in publishing. At moment, Chat Generative Pre-trained Transformer (ChatGPT) is one most powerful widely debated models. Here, we discuss its feasibility answer...

10.1093/humrep/dead207 article EN Human Reproduction 2023-10-13

Abstract STUDY QUESTION Do ongoing pregnancy rates (OPRs) differ in predicted hyperresponders undergoing ART after IVM of oocytes compared with conventional ovarian stimulation (OS) for IVF/ICSI? SUMMARY ANSWER One cycle is non-inferior to one OS women serum anti-Müllerian hormone (AMH) levels ≥10 ng/ml. WHAT IS KNOWN ALREADY Women high antral follicle count and elevated AMH levels, indicating an increased functional reserve, are prone hyperresponse during treatment. To avoid iatrogenic...

10.1093/humrep/dead273 article EN Human Reproduction 2024-01-04

Are low serum progesterone levels on the day of human chorionic gonadotrophin (hCG) administration detrimental for live birth delivery rates during in vitro fertilization (IVF)?Progesterone ≤0.5 ng/ml hCG hinder rates.Fundamental research has shown that presence late follicular phase is essential development, ovulation and endometrial receptivity. However, previous studies patients undergoing ovarian stimulation have only assessed if higher range are pregnancy or not. That said, information...

10.1093/humrep/deu151 article EN Human Reproduction 2014-06-17

Are clinical pregnancy rates satisfactory and the incidence of OHSS low after GnRH agonist trigger modified intensive luteal support in patients with a high risk ovarian hyperstimulation syndrome (OHSS)? combined 1500 IU hCG at time oocyte retrieval subsequent estradiol progesterone replacement high-risk can facilitate fresh embryo transfer severe OHSS. Conventional packages are inadequate to trigger. A dose (1500 IU) aspiration be used replace actions early LH sustain implantation function...

10.1093/humrep/det304 article EN Human Reproduction 2013-07-19

Is there any association between serum 25-OH vitamin D levels and ovarian reserve markers in infertile women? Vitamin is not associated with the markers, anti-mullerian hormone (AMH) antral follicle count (AFC), women. The mechanism underlying relationship deficiency reproduction still unclear; however, evidence indicates a potential direct negative impact on function. This mainly due to fact that gonadal function may be altered by deficiency, as observed expression of receptor mRNA human...

10.1093/humrep/dew304 article EN Human Reproduction 2016-11-07

Is elevated late-follicular phase progesterone (EP) associated with a deleterious impact on embryo quality (EQ) and cumulative live birth rates (LBRs)?EP was decrease in utilization LBRs.Ovarian stimulation promotes the production of (P) which adversely affects IVF pregnancy outcomes. However, evidence regarding potential association between EP an EQ is lacking.A retrospective analysis all GnRH antagonist down-regulated ICSI cycles followed by fresh transfer (ET) 2010 2015 performed. The...

10.1093/humrep/dey031 article EN Human Reproduction 2018-02-01

Is the effect of cell loss on further cleavage and implantation different for vitrified than slowly frozen Day 3 embryos?Vitrified embryos develop better overnight embryos, regardless number cells lost, but have similar potential if occurs overnight.After slow-freezing, rates been obtained intact 4-cell or with 1 damaged. For lower observed when at least 25% were lost. Other studies reported 7- to 8-cell 0, 2 No data are available development in relation damage.Survival retrospectively...

10.1093/humrep/det356 article EN Human Reproduction 2013-09-05

Is natural cycle frozen-thawed embryo transfer (NC-FET) associated with better clinical pregnancy rates (CPR) when compared to modified (mNC-FET)?NC-FET is a higher CPR mNC-FET.There conflicting evidence regarding the impact of hCG triggering on outcomes after (FET), and information effect luteal phase support (LPS) lacking.This retrospective study included all (n = 2353) consecutive cycles FET vitrified cleavage blastocyst stage embryos warmed between January 2010 April 2015 in tertiary...

10.1093/humrep/dew263 article EN Human Reproduction 2016-10-23
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