- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Advanced Radiotherapy Techniques
- Global Cancer Incidence and Screening
- Hernia repair and management
- Hip disorders and treatments
- Radiomics and Machine Learning in Medical Imaging
- Bladder and Urothelial Cancer Treatments
- Appendicitis Diagnosis and Management
- Genital Health and Disease
- Healthcare Systems and Technology
- Bone health and treatments
- Urinary Bladder and Prostate Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Primary Care and Health Outcomes
- Colorectal Cancer Surgical Treatments
- Osteoarthritis Treatment and Mechanisms
- T-cell and B-cell Immunology
- Cancer Immunotherapy and Biomarkers
- Urologic and reproductive health conditions
- Pancreatitis Pathology and Treatment
- Cervical Cancer and HPV Research
- Bone health and osteoporosis research
- Pancreatic and Hepatic Oncology Research
- Urinary and Genital Oncology Studies
London School of Hygiene & Tropical Medicine
2019-2023
Royal College of Surgeons of England
2019-2023
Whipps Cross University Hospital
2019-2022
Cambridge University Hospitals NHS Foundation Trust
2019-2021
University of Cambridge
2019
Florida College
2002
University of Florida
2002
Airedale General Hospital
1985
Objectives To assess the complications of transrectal (TR) compared to transperineal prostate (TP) biopsies. Patients and Methods Men diagnosed with cancer between 1 April 2014 31 March 2017 in England were identified National Prostate Cancer Audit. Administrative hospital data then used categorize type biopsy subsequent requiring admission. identify patients staying overnight immediately after those readmitted separately for admissions because sepsis, urinary retention or haematuria....
The prostate gland produces prostatic fluid, high in zinc and citrate essential for the maintenance of spermatozoa. Prostate cancer is a common condition with limited treatment efficacy castration-resistant metastatic disease, including immune checkpoint inhibitors. Using single-cell RNA-sequencing to perform an unbiased assessment cellular landscape human prostate, we identify subset tumor-enriched androgen receptor-negative luminal epithelial cells increased expression cancer-associated...
Abstract Background The five-tiered Cambridge Prognostic Group (CPG) classification is a better predictor of prostate cancer-specific mortality than the traditional three-tiered (low, intermediate, and high risk). We investigated radical treatment rates according to CPG in men diagnosed with non-metastatic cancer England between 2014 2017. Methods Patients were identified from National Prostate Cancer Audit database. Men risk stratified classification. Risk ratios (RR) estimated for...
Abstract Juxta‐articular defects pose significant challenges due to the high risk of fracture subchondral plate and articular cartilage. We evaluated mechanical histomorphological repair process caprine femoral augmented with either a bioresorbable in situ setting hydroxyapatite cement (HAC), polymethylmethacrylate (PMMA), autogenous bone graft (AG), or left empty. Twelve‐mm were made bilaterally medial condyles skeletally mature goats test material Femurs harvested at varying time periods...
Objectives To investigate whether patient‐reported urinary incontinence (UI) and bother scores after radical prostatectomy (RP) result in subsequent intervention with UI surgery. Patients Methods Men diagnosed prostate cancer the English National Health Service between April 2014 January 2016 were identified. Administrative data used to identify men who had undergone a RP those subsequently underwent procedure. The Prostate Cancer Audit database was also completed post‐treatment survey....
To report the 5-year failure-free survival (FFS) following high-intensity focused ultrasound (HIFU).This observational cohort study used linked National Cancer Registry data, radiotherapy administrative hospital data and mortality records of 1381 men treated with HIFU for clinically localised prostate cancer in England. The primary outcome, FFS, was defined as freedom from local salvage treatment cancer-specific mortality. Secondary outcomes were repeat HIFU, (CSS) overall (OS). Cox...
Sixty-five patients with benign ectopy of the uterine cervix were treated by cryosurgery in departments genitourinary medicine at St Luke's Hospital, Bradford, and Airedale General West Yorkshire, without analgesia or anaesthesia. A symptomatic cure rate 98% was achieved. There no serious complications. This treatment is considered to be appropriate clinics United Kingdom as these have routine screening procedures for various genital infections.
Despite femoral hernias being rarer than other groin hernias, records suggest they almost exclusively occur in older women, where the ring is wider.[1][1] Due to angle and narrow entry of canal, are typically more prone incarceration.[2][2] This case
Introduction & Aims: There is a current drive nationally to improve the management of acute ureteric colic. Management targets set by British Association Urological Surgeons (BAUS) include 4-week target for time from diagnosis-to-definitive management, or clinic review in patients managed expectantly. The motivation our stone service stemmed concerns that we did not have capacity consistently offer primary definitive treatment timely patients. We aimed restructure using Plan-Do-Study-Act...
Objective: This study aims to assess the effectiveness of Urology Advice and Guidance (A&G) referral pathway within National Health Service (NHS). It seeks identify whether A&G system helps prevent unnecessary referrals secondary care services endeavours see there is any variability in consultant responses queries, this affects how patients are subsequently managed. Patients methods: uses patient data collected by Cambridge University Hospitals NHS Foundation Trust over a six-month...