A5047154652- Orthopaedic implants and arthroplasty
- Bone fractures and treatments
- Spinal Fractures and Fixation Techniques
- Orthopedic Surgery and Rehabilitation
- Hip and Femur Fractures
- Spine and Intervertebral Disc Pathology
- Pelvic and Acetabular Injuries
- Foot and Ankle Surgery
- Shoulder Injury and Treatment
- Shoulder and Clavicle Injuries
- Hip disorders and treatments
- Total Knee Arthroplasty Outcomes
- Orthopedic Infections and Treatments
- Bone and Joint Diseases
- Tendon Structure and Treatment
- Medical Imaging and Analysis
- Trauma Management and Diagnosis
- Musculoskeletal pain and rehabilitation
- Rock Mechanics and Modeling
- Advanced X-ray and CT Imaging
- Lower Extremity Biomechanics and Pathologies
- Bone Tissue Engineering Materials
- Anatomy and Medical Technology
- Drilling and Well Engineering
- Knee injuries and reconstruction techniques
AO Foundation
2016-2025
University of Stuttgart
2023
Ansbach University of Applied Sciences
2023
Simulation Technologies (United States)
2023
University Hospital Münster
2013-2020
University of Münster
2012-2016
Center For Reconstructive Urethral Surgery
2014
Background and Objectives: Fracture healing is currently assessed through qualitative evaluation of radiographic images, which highly subjective in nature. Radiographs can only provide snapshots time, are limited due to logistics radiation exposure. We recently proposed assessing the bone status continuous monitoring implant load, utilizing an implanted sensor system, Monitor. The device telemetrically transmits statistically derived parameters via patient's mobile phone assist physicians...
Short-chain fatty acids (SCFAs) produced by the gut microbiota have previously been demonstrated to play a role in numerous chronic inflammatory diseases and be key mediators gut-bone signaling axis. However, of SCFAs bone fracture healing its impact on systemic inflammation during regeneration process has not extensively investigated yet. The aim this study was first determine effects SCFA butyrate cells involved vitro, namely, osteoclasts mesenchymal stromal (MSCs), second, assess if...
The management of fracture-related infection (FRI) with Debridement, Antibiotics, Irrigation, and Implant Retention (DAIR) is an appealing option, but its suitability restricted to a relatively narrow proportion patients. This study aimed create large animal model DAIR after FRI evaluate outcomes early (2 weeks) delayed (5 DAIR. Additionally, intramedullary lavage (IML) the canal (IMC) introduced as novel technique remove infected tissue. Our findings showed that failed resolve infections in...
Abstract Introduction Fractures of the odontoid process are associated with high non-union rates, challenging treatment, and incidence screw-related complications. The aim this study was to compare biomechanical competence a single biointegrative bone allograft screw versus two conventional cannulated screws for fracture fixation. Materials methods intact C2 vertebral specimens subjected quasi-static loading until fracture. Specimens an Anderson d’Alonzo type II or III ( n = 47) were fixated...
The present study contrasts the accuracy of different reconstructed models with distinctive segmentation methods performed by various experts. Seven research groups nine 3D one human femur based on an acquired CT image using their own computational methods. As a reference model for assessment, surface scan was created optical measuring system. Prior to comparison, divided into four areas; "neck and greater trochanter", "proximal metaphysis", "diaphysis", "distal metaphysis". deviation...
Periprosthetic hip fractures are an increasing problem in modern orthopedic and trauma surgery. Many options for the operative treatment available to surgeon ranging from variable angular systems standard plates, screws, cerclages. However, there is no gold therefore, aim of this study, was investigate biomechanical characteristics double plating versus a lateral plate Vancouver B1 fracture model. Ten 4th generation composite femora were used implant cementless total prosthesis create...
ABSTRACT Currently, evaluation of the stability spinal instrumentations often focuses on simple pull‐out or cyclic loading. However, loading characteristics and specimen alignment rarely simulate physiological conditions, clinical situation itself. The purpose this study was to develop an alternative setup parameters compare static dynamic pedicle screws at bone‐implant interface in lumbar osteoporotic cadavers. A corpectomy model development based ASTM‐1717 standard, allowing a deflection...
This study investigated the effects of a small posterior malleolar fragment (PMF), containing less than 25% articular surface area, on ankle joint stability via computed tomography (CT) scanning under full weight bearing in human cadaveric fracture model.A trimalleolar with PMF area was created 6 pairs fresh-frozen lower legs. The specimens were randomized into 2 groups stabilized by internal fixation including positioning screw for syndesmotic reconstruction. In Group I addressed direct...
In bone tissue engineering, the design of in vitro models able to recreate both chemical composition, structural architecture, and overall mechanical environment native is still often neglected. this study, we apply a bioreactor system where human bone-marrow hMSCs are seeded femoral head-derived decellularized scaffolds subjected dynamic culture, i.e., shear stress induced by continuous cell culture medium perfusion at 1.7 mL/min flow rate compressive 10% uniaxial load 1 Hz for h per day....
The augmentation of fixation with bone cement is increasingly being used in the treatment severe osteoporotic fractures. We investigated influence quality on mechanics plate a distal femoral fracture model (AO 33 A3 type). Eight and eight non-osteoporotic models were randomly assigned to either an augmented or non-augmented group. Fixation was performed using locking compression plate. In group additionally 1 ml injected into screw hole before insertion screw. Biomechanical testing axial...
The aim of this study was to identify the most responsive foot position for detection isolated unstable syndesmotic injury.
Background and Objectives: The aim of this study was to investigate under dynamic loading the potential biomechanical benefit simulated first tarsometatarsal (TMT-1) fusion with low-profile superelastic nitinol staples used as continuous compression implants (CCIs) in two different configurations comparison crossed screws locked plating a human anatomical model. Materials Methods: Thirty-two paired lower legs were randomized four groups for TMT-1 treatment via: (1) crossed-screws fixation...
Treating traumatic fractures in osteoporosis is challenging. Multiple clinical treatment options are found literature. Augmentation techniques promising to reduce treatment-related morbidity. In recent years, there have been an increasing number of reports about extended indication for augmentation techniques. However, biomechanical evaluations these limited.Nine thoracolumbar osteoporotic spinal samples (4 FSU) were harvested from postmortem donors and immediately frozen. Biomechanical...
The surgical fracture fixation of the odontoid process (dens) second cervical vertebra (C2/axis) is a challenging procedure, particularly in elderly patients affected by bone loss, and includes screw positioning close to vital structures. aim this study was provide an extended anatomical knowledge C2, mass distribution understand implications for anterior fixation. One hundred twenty standard clinical quantitative computed tomography (QCT) scans intact spine from 60 female male European...
Abstract Background The current standard of care for intervertebral disc (IVD) herniation, surgical discectomy, does not repair annulus fibrosus (AF) defects, which is partly due to the lack effective methods do so and why new strategies are widely investigated tested preclinically. There a need develop standardized IVD injury model in large animals enable comparison interpretation across preclinical study results. purpose this was compare vivo models sheep determine defect type combined...
Background and Objectives: Proximal humerus fractures (PHFs) are common in the elderly, but treatment results often poor. A clear understanding of fracture morphology distribution cortical bone loss is important for improved surgical decision making, operative considerations, new implant designs. The aim this study was to develop a 3D segmentation mapping technique create statistical description spatial pattern complex PHFs. Materials Methods: Fifty clinical computed tomography (CT) scans...