A5001257731- Viral Infections and Outbreaks Research
- Mosquito-borne diseases and control
- Malaria Research and Control
- Parasitic Diseases Research and Treatment
- Parasite Biology and Host Interactions
- Community Health and Development
- Leprosy Research and Treatment
- Disaster Response and Management
- Infectious Diseases and Tuberculosis
- Hepatitis B Virus Studies
- Zoonotic diseases and public health
- COVID-19 and Mental Health
- Vaccine Coverage and Hesitancy
- Global Maternal and Child Health
- Tuberculosis Research and Epidemiology
- Mental Health and Patient Involvement
- Liver Disease and Transplantation
- SARS-CoV-2 and COVID-19 Research
- Participatory Visual Research Methods
- Epilepsy research and treatment
- Disaster Management and Resilience
- Parasites and Host Interactions
- Geriatric Care and Nursing Homes
- Antibiotic Resistance in Bacteria
- Antibiotic Use and Resistance
Instituut voor Tropische Geneeskunde
2016-2024
Research Institute for Tropical Medicine
2022
Introduction The potential benefits of Mass Drug Administration (MDA) for malaria elimination are being considered in several endemic countries where a decline transmission has been reported. For this strategy to work, it is important that large proportion the target population participates, requiring an in-depth understanding factors may affect participation and adherence MDA programs. Methodology This social science study was ancillary one-round directly observed campaign with...
Abstract Background The importance of community involvement in the response against disease outbreaks has been well established. However, we lack insights into local communities’ experiences coping with current COVID-19 pandemic. This study explored both impact of, and to, within Orthodox Jewish communities Antwerp (Belgium) during first lockdown period (March 2020 – May 2020). Methods We conducted an explorative qualitative using a participatory approach. First, performed mapping to...
Abstract Background Reducing the risk of recurrent Plasmodium vivax malaria is critical for control and elimination. Primaquine (PQ) only widely available drug against P. dormant liver stages, but recommended as a 14-day regimen, which can undermine adherence to complete course treatment. Methods This mixed-methods study assess socio-cultural factors influencing PQ regimen in 3-arm, treatment effectiveness trial Papua, Indonesia. The qualitative strand, consisting interviews participant...
### Summary box How prepared were we for this most recent Ebola outbreak? Real-time emergent research is imperative successful response to global health emergencies. While innovative biomedical interventions are certainly important,1 local on-the-ground realities during the 2014–2015 West African epidemic demanded a different though complementary set of skills. Effective required deep, sensitive understandings dynamics and flexible, solution. Emergency intervention called evolving, flexible...
Although convalescent plasma (CP) transfusion was prioritized among potential Ebola treatments by the World Health Organization, there were concerns on feasibility of its implementation. We report successful organization donor mobilization and collection as part Ebola-Tx clinical trial from November 2014 to July 2015 in Conakry, Guinea. Project implementation registers, tools reports, mission minutes research team meetings used reconstruct sequence events how organized, plasmapheresis set...
During the 2014 Ebola Virus Disease (EVD) epidemic, Ebola-Tx trial evaluated use of convalescent plasma (CP) in Guinea. The effectiveness plasmapheresis trials depends on recruitment donors. This paper describes what motivated or deterred EVD survivors to donate CP, providing insights for future and epidemic preparedness.This qualitative study, part Ebola-Tx, researched addressed emergent difficulties through interviewing, participant observation focus group discussions. Sampling was...
Abstract Background: The importance of community involvement in the response against disease outbreaks has been well established. However, we lack insights into local communities’ experiences coping with current COVID-19 pandemic. This study explored both impact of, and to, within Orthodox Jewish communities Antwerp (Belgium) during first lockdown period (March 2020 – May 2020). Methods: We conducted an explorative qualitative using a participatory approach. First, performed mapping to...
Malaria elimination in the Greater Mekong Sub-Region is challenged by a rising proportion of malaria attributable to P. vivax. Primaquine (PQ) effective eliminating parasite's dormant liver stages and can prevent relapsing infections, but it induces severe haemolysis patients with Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency, highlighting importance testing enzyme activity prior treatment. A mixed-method study was conducted south-central Vietnam explore factors that affect...
Background A high prevalence of epilepsy has been observed in several onchocerciasis-endemic villages the Sanaga River basin, Cameroon. Recent studies suggest that ivermectin, a drug is distributed annually with aim eliminating onchocerciasis, may have protective effect against acquiring onchocerciasis-associated (OAE). This study, therefore, provides an in-depth understanding both complex therapeutic landscape for as well experiences related to ‘community-directed treatment ivermectin’...
To obtain the perspectives of some small- and medium-sized organizations on World Health Organization (WHO) prequalification programme for medicines to ascertain organizations' unmet needs.We conducted an exploratory, qualitative study in 2018 among 17 representatives 15 Belgian non-Belgian who purchase humanitarian, development or public programmes low- middle-income countries. We used semi-structured interviews respondents' views experiences using WHO guidance when procuring medicines....
Despite the global threat of antimicrobial resistance (AMR), evidence on use and quality medicines at community level is limited, particularly in impoverished, rural areas where prevalence (bacterial) infections high. To better understand processes that drive vulnerability to AMR’ effects, this study aimed assess social factors underpinning access to–and of–medical products healthcare, among people from Raglai ethnic minority Ninh Thuan Province, Vietnam. We conducted ethnographic research...
Background To reduce leprosy risk in contacts of patients with by around 50%, the World Health Organization (WHO) recommends post-exposure prophylaxis (PEP) using single-dose rifampicin (SDR). Results from a cluster randomized trial Comoros and Madagascar suggest that PEP double dose led to similar reduction incident leprosy, prompting need for stronger PEP. The objective this Phase 2 was assess safety bedaquiline-enhanced regimen (intervention arm, bedaquiline 800 mg 600 mg, BE-PEP),...
During the West African Ebola Virus Disease (EVD) epidemic from 2014 to 2016, a variety of technologies travelled considering context emergency: highly contagious fast-killing disease outbreak with no known remedy and rapidly increasing number cases. The Ebola-Tx clinical trial tested efficacy Convalescent Plasma (CP) as treatment for EVD in Guinea. This paper is based on ethnographic research focuses introduction mobile plasma collection centre, referred 'Plasma Mobile', equipped...
Since the World Health Organization (WHO) announced COVID-19 pandemic, attention has turned to impact of societal initiatives and what can be learned from them for future beyond COVID-19. Little been paid, however, how 'learning future,' as an organizational process, is concretely accomplished. This paper offers a collaborative autoethnography our team's project 'learn future' through transdisciplinary collaboration during first year where broader goal was help improve pandemic preparedness...
Abstract Background. Reducing the risk of recurrent P. vivax malaria is critical for control and elimination. Primaquine (PQ) only widely available drug against dormant liver stages, but recommended as a 14-day regimen, which can undermine adherence to complete course treatment. Methods. This mixed-methods study assess socio-cultural factors influencing PQ regimen in 3-arm, treatment effectiveness trial Papua, Indonesia. The qualitative strand, consisting interviews participant observation...