A5040472462- Acne and Rosacea Treatments and Effects
- Dermatologic Treatments and Research
- Skin Protection and Aging
- melanin and skin pigmentation
- Dermatology and Skin Diseases
- Nonmelanoma Skin Cancer Studies
- Facial Rejuvenation and Surgery Techniques
- Cutaneous Melanoma Detection and Management
- Cutaneous lymphoproliferative disorders research
- Contact Dermatitis and Allergies
- Nail Diseases and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Bee Products Chemical Analysis
- Retinoids in leukemia and cellular processes
- Body Contouring and Surgery
- Skin Diseases and Diabetes
- Hair Growth and Disorders
- Dermatological and COVID-19 studies
- Photodynamic Therapy Research Studies
- Advancements in Transdermal Drug Delivery
- Cancer and Skin Lesions
- Olfactory and Sensory Function Studies
- Pharmacological Effects of Natural Compounds
- Science and Science Education
- Chemotherapy-related skin toxicity
Pontifícia Universidade Católica de São Paulo
2024
Universidade Federal de São Paulo
2015-2024
Universidade do Estado do Rio de Janeiro
2024
Fundação de Apoio à Universidade Federal de São Paulo
2019-2024
ORCID
2021
Universidade Federal do Pará
2020
Universidade Federal de Minas Gerais
2011
Hospital São Paulo
2010
Associação Paulista de Medicina
2000
Universidade de Sorocaba
1995
BACKGROUND: Acne is a common disease in adolescents, but there are no epidemiological data for acne Brazil. OBJECTIVES: To estimate the prevalence and degree of adolescents from Sao Paulo study socio-demographic factors, family history lifestyle, associated with disease. METHODS: Cross-sectional 452 aged between 10 17 (mean=13.3 years), students elementary high school, examined by 3 independent evaluators. RESULTS: 62.4% were female, 85.8% white 6.4% 14. The was 96.0% increased age - all...
Isotretinoin is a synthetic retinoid, derived from vitamin A, with multiple mechanisms of action and highly effective in the treatment acne, despite common adverse events, manageable dose-dependent. Dose-independent teratogenicity most serious. Therefore, off-label prescriptions require strict criteria.To communicate experience recommendation Brazilian dermatologists on oral use drug dermatology.Eight experts five universities were appointed by Society Dermatology to develop consensus...
Melasma can be refractory to treatment, and relapses are frequent. Thiamidol is a new potent tyrosinase inhibitor that has been found effective as cosmeceutical for the depigmenting of melasma.This study compared efficacy tolerability topical 0.2% vs. 4% hydroquinone facial melasma.Fifty women with melasma participated in randomized, evaluator-blinded, controlled from September through November 2020. Patients were randomly assigned apply double layer twice day or cream at bedtime, 90 days....
The gynoidlypodystrophy, known as cellulitis or cellulite, refers to a condition that gives the skin an undulating and uneven appearance, affecting 80-90% of women after puberty.to investigate efficacy safety manual lymphatic drainage for cellulite management.this was open, prospective, intervention study including 20 aged from 40 years. Fourteen sessions were performed once week on lower limbs buttocks.Fifteen completed study. A significant improvement quality life observed (p=0.018)....
The data that support the findings of this study are available from corresponding author upon reasonable request. participants in manuscript have given written informed consent to publication their case details. Ethical approval: This protocol was approved by FMB-Unesp Institutional Review Board (No. 4.767.182). Trial registration: ReBEC - ensaiosclinicos.gov.br – RBR-10gx2qhj.
Oral isotretinoin is the criterion standard treatment for severe inflammatory acne associated with scar development. Atypical or exaggerated cicatrization related to oral was reported throughout 1980s and 1990s. Dermabrasion atrophic revision not recommended 6 12 months from end of treatment.To evaluate wound healing after localized dermabrasion in patients receiving isotretinoin.Interventional, prospective study involving seven taking treat scars on face. Manual performed all an area...
The clinical significance of nevus-associated melanoma compared with de novo melanomas remains controversial. It has been suggested that have a higher Breslow thickness and therefore worse prognosis. Over 10-year period, this study evaluated the incidence its prognostic related to clinicopathologic features.Cross-sectional from 1995 through 2004 in dermatopathology referral center. With available data, we sex, primary location, histologic subtype, thickness, Clark level, presence ulceration,...
Background Oral isotretinoin (ISO) is the only drug which promotes prolonged remission or cure of severe acne. It also has other properties, supporting its use for non-acne indications. Retinoic acid (RA) gold standard treatment photoaging. ISO photoaging was reported in non-controlled trials as alternative to RA, causes skin irritation. Objective To compare clinical, histological, and immunohistochemical effects low-dose 0.05% topical RA treat Methods Randomized, comparative,...
The origin of melanoma has always been a debated subject, as well the role adjacent melanocytic naevi. Epidemiological and histopathological studies point to melanomas arising either de novo or from naevus.To evaluate presence mutations in genes well-known melanomagenesis pathways large series naevus-associated melanomas.Sixty-one found association with pre-existing naevus were microdissected, after careful selection cell subpopulations, submitted Sanger sequencing BRAF, NRAS, c-KIT, PPP6C,...
Background The efficacy of low-dose oral isotretinoin in the treatment seborrhea and seborrheic dermatitis has been poorly investigated randomized studies. Objectives This study was designed to determine safety moderate severe on scalp and/or face. Methods A randomized, comparative clinical trial, using two groups, conducted over 6 months. Patients Group ISO were treated with 10 mg every other day. In X, patients received antiseborrheic topical treatment. Patient opinion, investigator...
Abstract Objective To assess the efficacy and safety of topical 5% cysteamine versus 4% hydroquinone in treatment facial melasma women. Topical is an antioxidant tyrosinase inhibitor that has been shown to be effective melasma. However, date, no study compared performance for Methods A quasi‐randomized, multicenter, evaluator‐blinded clinical trial was conducted on 40 women with who were submitted nightly application (CYS) or (HQ) hyperpigmented areas 120 days. Both groups required use...