- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Disaster Response and Management
- Viral Infections and Outbreaks Research
- Animal Virus Infections Studies
- Disaster Management and Resilience
- Vaccine Coverage and Hesitancy
- Healthcare Systems and Technology
- Heparin-Induced Thrombocytopenia and Thrombosis
- Innovative Teaching and Learning Methods
- Cognitive Abilities and Testing
- Cardiac Arrest and Resuscitation
- Renal Diseases and Glomerulopathies
- Substance Abuse Treatment and Outcomes
- Behavioral Health and Interventions
- Chronic Kidney Disease and Diabetes
- Patient-Provider Communication in Healthcare
- Autoimmune Bullous Skin Diseases
- Viral gastroenteritis research and epidemiology
- Crime Patterns and Interventions
- Interprofessional Education and Collaboration
- Disability Education and Employment
- Educational and Psychological Assessments
- Online and Blended Learning
- Patient Satisfaction in Healthcare
Public Health Ontario
2022
Sunnybrook Health Science Centre
2020-2022
Health Sciences Centre
2020-2022
University of Toronto
2021-2022
Lunenfeld-Tanenbaum Research Institute
2022
Western University
2022
The Scarborough Hospital
2021
Sunnybrook Research Institute
2019-2020
Newman University
2020
Sunnybrook Hospital
2019
<h3>Importance</h3> Patients undergoing hemodialysis have a high mortality rate associated with COVID-19, and this patient population often has poor response to vaccinations. Randomized clinical trials for COVID-19 vaccines included few patients kidney disease; therefore, vaccine immunogenicity is uncertain in population. <h3>Objective</h3> To evaluate the SARS-CoV-2 antibody chronic following 1 vs 2 doses of BNT162b2 vaccination compared health care workers serving as controls convalescent...
<h3>Background:</h3> Differences in immunogenicity between mRNA SARS-CoV-2 vaccines have not been well characterized patients undergoing dialysis. We compared the serologic response maintenance hemodialysis after vaccination against with BNT162b2 (Pfizer-BioNTech) and mRNA-1273 (Moderna). <h3>Methods:</h3> conducted a prospective observational cohort study at 2 academic centres Toronto, Canada, from Feb. 2, 2021, to July 20, which included 129 95 who received vaccines, respectively. measured...
Abstract The contours of endemic coronaviral disease in humans and other animals are shaped by the tendency coronaviruses to generate new variants superimposed upon nonsterilizing immunity. Consequently, patterns reinfection can inform emerging state SARS-CoV-2 pandemic. We generated controlled data after high low risk natural exposure or heterologous vaccination sialodacryoadenitis virus (SDAV) rats. Using deterministic compartmental models, we utilized vivo estimates from these experiments...
Severe, nonresponsive, primary focal segmental glomerular sclerosis (FSGS) can progress to end-stage kidney disease (ESKD) in <5 years. Soluble urokinase-type plasminogen activator receptor (suPAR) may contribute podocyte effacement by activating β3 integrin. It has been reported as a potential permeability factor and biomarker for FSGS. Rituximab was found have efficacy case reports small series. Whether rituximab is efficacious patients with treatment-resistant FSGS the context of high...
Research on the implementation of patient decision aids to facilitate shared making in clinical settings has steadily increased across Western countries. A study which implements and measures their impact yet be conducted Eastern part Europe.To use Option GridTM a sample Grupa LUX MED clinics Warsaw, Poland, measure making.We pre-post interventional study. Following three-month period usual care, clinicians from three received one-hour training session how were provided with copies for four...
Implicit alcohol-related cognitions develop during adolescence and are thought to play an important role in the etiology of adolescent alcohol use. Rooted reciprocal determinism, a developmental theory cognitions, current study sought enhance our understanding development automatic associations their relationship with To provide theoretically aligned test we used latent change score models examine whether growth use was related each other (between-person effects) construct led changes over...
Abstract Importance Hemodialysis patients have an exceptionally high mortality from COVID-19 and this patient population often has a poor response to vaccinations. Randomized controlled trials for vaccines included few with kidney disease, therefore vaccine immunogenicity is uncertain in population. Objective Evaluate the SARS-CoV-2 antibody chronic hemodialysis following one versus two doses of BNT162b2 vaccination compared health care worker controls convalescent serum. Design Prospective...
Improving the provision of supportive care for patients with Ebola is an important quality improvement initiative. We designed a simulated Treatment Unit (ETU) to assess performance and safety healthcare workers (HCWs) performing tasks wearing personal protective equipment (PPE) in hot (35 °C, 60% relative humidity) or thermo-neutral (20 20% conditions. In this pilot phase determine feasibility study procedures, HCWs PPE were non-randomly allocated conditions perform peripheral intravenous...
<h3>Contexte:</h3> Les différences d’immunogénicité entre les vaccins anti-SRAS-CoV-2 à ARNm n’ont pas été bien caractérisées chez patients hémodialysés. Nous avons comparé la réponse sérologique sous hémodialyse après vaccination contre le SRAS-CoV-2 au moyen des BNT162b2 (Pfizer-BioNTech) et mRNA-1273 (Moderna). <h3>Méthodes:</h3> procédé une étude de cohorte observationnelle prospective dans 2 centres universitaires Toronto, Canada, du février 20 juillet 2021, inclus 129 95 qui ont reçu...
Students’ Perceptions about a Collaboratively Designed Behaviour Improvement Policy: An Exploratory Ethnographical Study