A5084160810- Genetics and Physical Performance
- Sports Performance and Training
- Muscle metabolism and nutrition
- Cardiovascular Effects of Exercise
- Adipose Tissue and Metabolism
- Cardiovascular and exercise physiology
- Sports injuries and prevention
- Thermoregulation and physiological responses
- Exercise and Physiological Responses
- Health and Lifestyle Studies
- Body Composition Measurement Techniques
- Obesity, Physical Activity, Diet
- Mitochondrial Function and Pathology
- Sports and Physical Education Studies
- Neurobiology and Insect Physiology Research
- Advanced Chemical Sensor Technologies
- Ion Transport and Channel Regulation
- Financial Reporting and Valuation Research
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Auditing, Earnings Management, Governance
- Behavioral Health and Interventions
- Ion channel regulation and function
- Legionella and Acanthamoeba research
- Sport Psychology and Performance
- Bioactive natural compounds
University of Puerto Rico System
2003-2020
University of Pamplona
2020
Florida Institute of Technology
2019
Technological University of the Mixteca
2018
Universidade Federal da Bahia
2010
Universidad Nacional Autónoma de México
2009
University of Puerto Rico at Río Piedras
1985-2009
Pennington Biomedical Research Center
2001-2007
Universidad de Guadalajara
2006-2007
University of Puerto Rico, Medical Sciences Campus
1993-2005
Several studies have reported that the insertion (I) allele of angiotensin-converting enzyme ( ACE) I/deletion (D) polymorphism is associated with enhanced responsiveness to endurance training and more common in athletes than sedentary controls. We tested latter hypothesis a cohort 192 male maximal oxygen uptake ≥75 ml ⋅ kg −1 min 189 The ACE ID intron 16 was typed three-primer polymerase chain reaction method. Both genotype P = 0.214) 0.095) frequencies were similar Further analyses...
This study examined the nutritional and performance status of elite soccer players during intense training. Eight male (age 17+/-2 years) Puerto Rican Olympic Team recorded daily activities food intake over 12 days. Daily energy expenditure was 3,833+/-571 (SD) kcal, 3,952+/-1,071 which 53.2+/-6.2% (8.3 g x kg BW(-1)) from carbohydrates (CHO), 32.4+/-4.0% fat, 14.4+/-2.3% protein. With exception calcium, all micronutrients were in accordance with dietary guidelines. Body fat 7.6+/-1.1% body...
This study examined the association between a DNA polymorphism in muscle-specific creatine kinase (CKMM) gene and ˙VO2max sedentary state, as well its response (Δ˙VO2max) to standardized 20-wk endurance training program. The subjects were 160 biologically unrelated Caucasian parents (80 women, 80 men) adult offspring of HERITAGE Family Study. CKMM was detected by PCR digestion with NcoI restriction enzyme. measured during maximal cycle ergometer tests. 2119 ± 45 mL·min-1 (mean SE) or 26 0.4...
Linkage between a muscle-specific CK gene marker and V̇O2max in the HERITAGE Family Study. Med. Sci. Sports Exerc., Vol. 31, No. 5, pp. 698-701, 1999. Purpose: We have reported significant association sedentary state its response (Δ V̇O2max) to an endurance training program with creatine kinase (CKMM) polymorphism. The purpose of this study was test hypothesis genetic linkage same CKMM as well Δ V̇O2max. Methods: Sib-pair analysis performed on 277 full sib-pairs from 98 Caucasian nuclear...
WOLFARTH, B., M. A. RIVERA, J-M. OPPERT, R. BOULAY, F. T. DIONNE, CHAGNON, J. GAGNON, Y. L. PÉRUSSE, KEUL, and C. BOUCHARD. A polymorphism in the alpha2a-adrenoceptor gene endurance athlete status. Med. Sci. Sports Exerc., Vol. 32, No. 10, pp. 1709–1712, 2000. Purpose In a case control study, we examined allelic frequencies genotype distributions of two restricted fragment length polymorphisms (RFLP) alpha-2A-adrenoceptor (ADRA2A) beta-2-adrenoceptor (ADRB2) among elite athletes (EEA)...
The purpose of this study was to test the effect increased fluid intake on temperature regulation and performance in elite soccer players. Eight players Puerto Rico National Team were studied under field conditions at a Wet Bulb Globe Temperature (WBGT) heat stress index 25.3 +/- 0.5 degrees C. They young (17.0 0.6 yr) well aerobically conditioned, as shown by their maximum aerobic power 69.2 0.7 ml.kg(-1).min(-1). Players randomly allocated week voluntary hydration (VH) (fluid = 2.7...
The purpose of this study was to investigate the association between elite endurance athlete (EEA) status and two restriction fragment length polymorphisms (RFLPs) at muscle-specific creatine kinase (CKMM) gene locus. Genomic DNA extracted from white blood cells or lymphoblastoid cell lines 124 unrelated Caucasian male EEA (˙VO2max >73 mL·kg-1·min-1) 115 sedentary controls (SCON). genetic polymorphism CKMM locus detected by polymerase chain reaction digestion with theNcoI TaqI endonucleases....
This study examined the associations between elite endurance athlete (EEA) status and three mitochondrial DNA (mtDNA) restriction fragment length polymorphisms (RFLPs) in subunit 5 of NADH dehydrogenase (MTND5) locus one D-loop region. A group 125 Caucasian male EEA well endowed with phenotypic expression ˙VO2max (78.9 ± 3.8 mL·kg-1·min-1, mean SD) 65 sedentary controls (SCON: = 39.8 8.2 mL·kg-1·min-1) participated study.˙VO2max was determined during an incremental exercise test on a cycle...
Intrinsic body fluid regulation is critical for optimizing endurance performance. Aquaporins (AQPs) are a family of transmembrane proteins that transport water and glycerol across cellular membranes. A recent report revealed an association between single nucleotide polymorphism (SNP) in the 3' untranslated region aquaporin-1 (AQP1) gene The purpose study was to explore AQP1 SNP acute loss long distance runners. subjects (N=91, Age=26±3 yrs; Ht=170±11 cm; Wt=61±5 kg; mean±SD) were...
Certain G-rich DNA repeats can form quadruplex in bacterial chromatin that present blocks to replication and, if not properly resolved, may lead mutations. To understand the participation of genomic instability Escherichia coli (E. coli), mutation rates were measured for quadruplex-forming repeats, including (G3T)4, (G3T)8, and a RET oncogene sequence, cloned as template or nontemplate strand. We evidence these alternative structures strongly influence mutagenesis rates. Precisely, our...
We examined the possible association between a transforming growth factor (TGF)-β 1 gene polymorphism in codon 10 and blood pressure (BP) at rest, acute response to exercise pretrained (sedentary) trained states, as well its training (Δ) 20 wk of endurance exercise. Subjects were 257 black 480 white, healthy sedentary normotensive subjects from HERITAGE Family Study. The was detected by polymerase chain reaction digestion with Msp A1 I endonuclease yielding wild (leucine-10) mutant...
Introduction and aim of the study: We examined association between a DNA sequence variant in aquaporin-1 (AQP1) gene performance Hispanic marathon runners. Materials methods: samples (N = 784) were obtained from apparently healthy, biologically unrelated, ethni- cally matched runners who participated international level marathons Spain Mexico. Cases (n 396; men= 225; women=171) finished top 3 rd percentile for their age gender, while Controls 388; men=221 women=167) lowest percentile. The...
This study examined the applicability of criteria for maximal oxygen consumption (V̇O 2 max) in adolescents. Active females ( n =38) and males =196) who were students at a sports-technical junior high school performed treadmill Bruce protocol to volitional fatigue. The V̇O max R ≥1.0, HR ≥95% predicted age, an increase ≤2.1 ml·kg −1 ·min with workload. first criterion was met by 97% 93% males, while 81% 75% second criterion. Only 8% 13% third Those achieved plateau showed higher peak...
Abstract The purposes of this study were to examine the thermoregulatory and body fluid balance responses in chronically heat acclimatized children, i.e., indigenous a tropical climate, during exercise four outdoor conditions effects dehydration on their response. Nine children (age = 13.3 ± 1.9 yr, VO 2 max 45.5 9.2 ml · kg −1 min ) cycled at 60% each under conditions: sun exposure voluntary drinking (SuVD), forced (SuFD), shaded (ShVD), (ShFD). Exercise sessions consisted 20‐min bouts...