A5041441599- Infections and bacterial resistance
- Enterobacteriaceae and Cronobacter Research
- Pneumonia and Respiratory Infections
- Global Maternal and Child Health
- Vaccine Coverage and Hesitancy
- Streptococcal Infections and Treatments
- COVID-19 epidemiological studies
- Global Health and Surgery
- Health Policy Implementation Science
- Salmonella and Campylobacter epidemiology
- Respiratory viral infections research
- Health Systems, Economic Evaluations, Quality of Life
- Antibiotic Resistance in Bacteria
- Global Health Workforce Issues
- Migration and Labor Dynamics
- Blood disorders and treatments
- Vibrio bacteria research studies
- Global Public Health Policies and Epidemiology
- Global Health and Epidemiology
- Aquaculture disease management and microbiota
- Ethics in Clinical Research
- Healthcare Systems and Reforms
- Child and Adolescent Health
- Sepsis Diagnosis and Treatment
- Bacterial Identification and Susceptibility Testing
MRC Unit the Gambia
2022-2025
There is a lack of data on the time to blood culture positivity (TTP) in pediatric populations low-income countries. We aimed assess host and pathogen factors associated with TTP children aged under 5 years rural Gambia. Between September 2019 December 2023, we collected cultures from suspected bloodstream infections. determined incubation when bacterial growth was first detected. Overall, 547 invasive bacteria pathogens were evaluated. The median 19.2 hours 70%, 76%, 89%, 96% cases had at...
Background In low-resource settings, it is challenging to ascertain the burden and causes of under-5 mortality as many deaths occur outside health facilities. We aimed determine childhood in rural Gambia using verbal autopsies (VA). Methodology used WHO VA questionnaires conduct VAs for years age Basse Fuladu West Health Demographic Surveillance Systems (HDSS) between September 01, 2019, December 31, 2021. Using a standardized cause death list, two physicians assigned discordant diagnoses...
Key Clinical Message Ochrobactrum anthropi ( O . ), a rare opportunistic pathogen, caused sepsis in malnourished 15‐month‐old African child. Early detection and appropriate antibiotics led to full recovery, highlighting the importance of robust surveillance for emerging pathogens vulnerable populations. Abstract While rarely causing infections, , non‐fermenting, obligately aerobic, flagellated gram‐negative bacillus, demonstrates oxidase positivity indole negativity. Traditionally, spp is...
The COVID-19 pandemic represents an unprecedented challenge for clinical research. Pneumococcal Vaccine Schedules (PVS) study is a non-inferiority, interventional trial in which infants resident 68 geographic clusters are randomised to two different schedules pneumococcal vaccination. From September 2019 onwards, all the area became eligible enrolment at Expanded Programme on Immunisation (EPI) clinics area. Surveillance endpoints conducted 11 health facilities PVS as collaboration between...
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Abstract Background Stenotrophomonas maltophilia is a gram-negative bacteria known for causing opportunistic and nosocomial infections in humans. S. an emerging pathogen of concern due to it’s increasing prevalence, diverse disease spectrum, intrinsic multi-drug resistance high mortality rates immunocompromised individuals. rare cause neonatal sepsis associated with significant morbidity mortality. The bacterium’s poses considerable challenge treatment, various mechanisms contributing its...
Without complete data on under-5 mortality, tracking progress towards achieving Sustainable Development Goal 3.2 will be challenging. Such are also needed to ensure proper planning and prioritisation of scarce resources in low-income middle-income countries. However, most countries have weak Civil Registration Vital Statistics (CRVS) systems, leaving a critical gap understanding mortality dynamics. This paper outlines community-based approach enhance surveillance countries, using The Gambia...
Enterobacter cloacae is the leading cause of morbidity and mortality in genus Enterobacter. It mostly causes nosocomial infections, especially children, elderly those with underlying diseases. However, cases community-acquired bacteraemia caused by E. have been reported. The increasing inclination to multidrug-resistant infections has made it particularly challenging treat. A 25-month-old male child presented a rural hospital Gambia one-week history persistent high-grade fever, dyspnoea,...
<title>Abstract</title> <bold>Background</bold> The migration of healthcare professionals from developing countries to more developed nations poses a significant challenge systems in low- and middle-income countries. This study aimed determine the proportion doctors Ghana who intend migrate abroad identify sociodemographic "pull push" factors that influence their intention. <bold>Methodology</bold> A cross-sectional survey was conducted among between March 1, 2024, 15, via an online-based...
Background: Aeromonas hydrophila, a Gram-negative, motile, facultative anaerobe, is emerging as serious pathogen. It found in water, soil, and food, causing various infections, from mild diarrhoea to life-threatening sepsis. Young children, older people, immunocompromised people are most susceptible. While treatable with antibiotics, A. hydrophila’s growing resistance penicillin other commonly available antibiotics complicates treatment. This case report highlights rare instance of...
<title>Abstract</title> Randomized controlled trials are considered the “gold standard” for evaluating effectiveness of an intervention. However, large-scale, cluster-randomized complex and costly to implement. The generation accurate, reliable, high-quality data is essential ensure validity generalizability findings. Robust quality assurance control procedures important optimize validate quality, accuracy, reliability trial data. To date, few studies have reported on study assess integrity...
Abstract Background The migration of healthcare professionals from developing countries to more developed nations poses a significant challenge systems in low- and middle-income countries. This study aimed determine the proportion doctors Ghana who intend migrate abroad identify sociodemographic "pull push" factors that influence their intention. Methodology A cross-sectional survey was conducted among between March 1, 2024, 15, via an online-based semi-structured questionnaire. Doctors...
Abstract Background In low-resource settings, it is challenging to ascertain the burden and causes of under-5 mortality as many deaths occur outside health facilities. Verbal autopsy (VA) an important tool that provides data on death in communities with limited access care. We aimed determine childhood by VA rural Gambia. Methodology used WHO standard questionnaires conduct VAs for years age Basse Fuladu West Health Demographic Surveillance Systems Gambia between September 01, 2019, December...
Abstract The COVID-19 pandemic represents an unprecedented challenge for clinical research. Pneumococcal Vaccine Schedules (PVS) study is a non-inferiority, interventional trial in which infants resident 68 geographic clusters are randomised to two different schedules pneumococcal vaccination. From September 2019 onwards, all the area became eligible enrolment at Expanded Programme on Immunisation (EPI) clinics area. Surveillance endpoints conducted 11 health facilities PVS as collaboration...