Yuewen Zhai

ORCID: 0000-0001-7273-9056
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About
Contact & Profiles
Research Areas
  • RNA Interference and Gene Delivery
  • Immunotherapy and Immune Responses
  • Nanoplatforms for cancer theranostics
  • Immune cells in cancer
  • Extracellular vesicles in disease
  • Cancer Research and Treatments
  • Immune Cell Function and Interaction
  • CAR-T cell therapy research
  • Nanoparticle-Based Drug Delivery
  • Electrospun Nanofibers in Biomedical Applications
  • Pluripotent Stem Cells Research
  • Advanced Nanomaterials in Catalysis
  • CRISPR and Genetic Engineering
  • Hematopoietic Stem Cell Transplantation
  • Cancer, Hypoxia, and Metabolism
  • Advanced biosensing and bioanalysis techniques
  • Phagocytosis and Immune Regulation

China Pharmaceutical University
2021-2024

State Key Laboratory of Natural Medicine
2021-2024

Dilated erythrocyte membrane specifically transfer iPSC to spleen for effective tumor prevention.

10.1126/sciadv.abi6326 article EN cc-by-nc Science Advances 2021-08-25

As an efficient tumor immunotherapy, PD-1 antibody has been gradually used in clinical treatment, but the low response rate and excessive immune limit its extensive application.Herein, a therapeutic regime for reinvigoration activation of microenvironment is introduced to improve anti-tumor effect antibody. To comprehensively immunotherapy reduce response, biomimetic cascade targeting nanosystem, siRNA@PLOV, which was fused by photothermal sensitive liposomes (PTSLs) attenuated Salmonella...

10.1186/s12951-021-01193-9 article EN cc-by Journal of Nanobiotechnology 2021-12-01

10.1038/s41551-024-01323-2 article EN Nature Biomedical Engineering 2024-12-27

<div>Abstract<p>Cancer vaccines are an approach to elicit amplified antigen-specific immune responses. Induced pluripotent stem cells (iPSC) have potential utility for the development of universal because their intrinsic antigenic epitopes. Concurrently, iPSCs can undergo differentiation and thus a stable source both antigen-presenting producing cell-based tumor organoids facilitating exploration adaptive assessment vaccines. This review describes specific contributions vaccine...

10.1158/0008-5472.c.7474423 preprint EN 2024-10-01
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