A5008680645- HIV, Drug Use, Sexual Risk
- HIV/AIDS Research and Interventions
- Opioid Use Disorder Treatment
- Infection Control and Ventilation
- Hepatitis C virus research
- PI3K/AKT/mTOR signaling in cancer
- Emergency and Acute Care Studies
- Innovations in Medical Education
- Mental Health and Patient Involvement
- Protein Kinase Regulation and GTPase Signaling
- Long-Term Effects of COVID-19
- Cardiac Arrest and Resuscitation
- Substance Abuse Treatment and Outcomes
- HIV Research and Treatment
- COVID-19 and healthcare impacts
- Prenatal Substance Exposure Effects
- COVID-19 Clinical Research Studies
- Diabetes Management and Education
- Patient Satisfaction in Healthcare
- Psychiatric care and mental health services
- HIV/AIDS drug development and treatment
- Empathy and Medical Education
- Homelessness and Social Issues
- Receptor Mechanisms and Signaling
- Primary Care and Health Outcomes
University of South Carolina
2019-2025
Clemson University
2021-2025
Prisma Health
2019-2025
East Carolina University
2025
Prisma
2024-2025
Society of Critical Care Medicine
2021-2022
John Wiley & Sons (United Kingdom)
2022
eHealth Initiative
2022
Proteogenomics Research Institute for Systems Medicine
2019
Emory University
2019
While several studies have focused on preliminary data and outcomes associated with prehospital buprenorphine administration interventions, to date there has been little discussion of the challenges experienced during initial implementation a protocol. In this case series we examine 3 separate patient encounters different crews, patients, receiving emergency medicine (EM) physicians, which highlight implementing first program in rural Appalachian County within South Carolina. 2 cases...
Personal attitudes amongst emergency medical services (EMS) clinicians could influence successful implementation of prehospital buprenorphine administration programs (PBAPs), yet few studies have investigated EMS clinician perceptions concerning these innovative programs. This mixed-methods study assessed and concerns about PBAPs. Emergency Medical Technicians (EMTs), advanced EMTs paramedics were recruited for focus groups from Upstate South Carolina. Researchers moderated 12 or fewer field...
Ubiquitin-mediated protein degradation is necessary for both increased ventricular mass and survival signaling compensated hypertrophy in pressure-overloaded (PO) myocardium. Another molecular keystone involved the hypertrophic growth process mammalian target of rapamycin (mTOR), which forms two distinct functional complexes: mTORC1 that activates p70S6 kinase-1 to enhance synthesis mTORC2 Akt promote cell survival. Independent studies animal models show treatment alters mTOR complexes also...
Interpersonal and communication skills are core competencies for nursing students. Empathetic, patient-centred improves patient outcomes the care experience. Nursing trainees have reported a lack of preparation confidence in interpersonal with patients members health team. Acting-based hands-on training may provide novel approach to develop
Abstract Peritonitis is a common complication for patients with end‐stage renal disease undergoing peritoneal dialysis (PD) and direct cause or contributor in >15% deaths PD patients. Since early detection key to treatment, their care teams need rapid, on‐site diagnostics. A hydrogel‐based fluid pH sensor attached catheter developed measure local acidosis indicative of infections monitoring using X‐ray imaging. The comprises polyacrylic acid hydrogel embedded radiopaque markers enclosed...
Cautious optimism suggests that the COVID-19 pandemic in United States has reached a turning point. Cases have declined precipitously from their heights early winter months and vaccine distribution administration moved ahead at an accelerated pace. As of late March, more than 140 million doses had been administered States, with 27% population receiving least one dose.1 Nevertheless, challenges remain. Rates are increasing select parts country, as nonpharmaceutical interventions such mask...
In 2012, the Society for Academic Emergency Medicine convened a consensus conference on state of medical education research with goals defining and advancing future agenda. Since that time, emergency medicine (EM) has grown significantly. A task force EM experts was assembled sought to understand current directions. Among advances are increases in fellowships, advanced degree certification programs, faculty development publication venues, funding. These findings discussed light prior...
Coronavirus disease 2019 (COVID-19) has spread around the world and caused hundreds of thousands fatalities across a wide spectrum patients with varying severity presenting complaints. The discussion ability this to cause significant illness in various risk factors such as myasthenia gravis is important help guide physicians on recognition treatment options pandemic matures.Here we discuss single case isolated COVID-19 infection that precipitated myasthenic crisis no other clinical sequelae...
We estimated the seroprevalence of both acute and chronic HIV infection by using a random sample emergency department (ED) patients from region United States with low-to-moderate prevalence.This cross-sectional study consecutively enrolled aged 18 to 64 years within randomly selected sampling blocks in Midwestern urban ED lower prevalence 2008 2009. Participants were compensated for providing blood health information. After de-identification, we assayed samples antibody nucleic acid.There...
Abstract Introduction Emergency departments (ED) are incorporating Peer Support Specialists (PSSs) to help with patient care for substance use disorders (SUDs). Despite rapid growth in this area, little is published regarding workflow, expectations of the peer role, and core components PSS intervention. This study describes these elements a national sample ED-based support intervention programs. Methods A survey was conducted assess site characteristics as part selection process National...
To understand shift-level determinants of emergency physician (EP) burnout, relationships were tested between EP shift demands, stress, and fatigue.
Connective tissue growth factor (CTGF) is a fibrogenic cytokine that promotes fibrosis in various organs. In the heart, both cardiomyocytes (CM) and cardiac fibroblasts have been reported as source of CTGF expression, aiding fibrosis. Although mammalian target rapamycin (mTOR) forms 2 distinct complexes, mTORC1 mTORC2, plays central role integrating biochemical signals for protein synthesis cellular homeostasis, we explored its expression adult feline CM. CM were stimulated with 10 μM...
Hepatitis C virus (HCV) is an infection of the liver that can lead to significant damage and hepatocellular carcinoma. Individuals born between 1945 1965 individuals with intravenous drug use represent largest HCV demographics often experience barriers treatment. In this case series, we discuss a novel partnership community paramedics (CPs), care coordinators, infectious disease physician provide treatment accessing care.Three patients tested positive for within large hospital system in...
Abstract Objectives To overcome the shortage of personal protective equipment and airborne infection isolation rooms (AIIRs) in COVID‐19 pandemic, a collaborative team research engineers clinical physicians worked to build novel negative pressure environment hopes improving healthcare worker patient safety. The then sought test device's efficacy generating maintaining pressure. goal proved prescient as US Food Drug Administration (FDA) later recommended that all barrier devices use Methods...