A5012598751- Estrogen and related hormone effects
- Hepatitis C virus research
- HIV, Drug Use, Sexual Risk
- Traumatic Brain Injury and Neurovascular Disturbances
- Mental Health Treatment and Access
- Diabetes Management and Education
- Opioid Use Disorder Treatment
- Substance Abuse Treatment and Outcomes
- Health Policy Implementation Science
- Cancer Treatment and Pharmacology
- Pregnancy and preeclampsia studies
- 14-3-3 protein interactions
- Microtubule and mitosis dynamics
- Pregnancy and Medication Impact
- HIV/AIDS drug development and treatment
- Viral-associated cancers and disorders
- Mental Health and Patient Involvement
- HIV/AIDS Research and Interventions
- Orthopedic Infections and Treatments
- Total Knee Arthroplasty Outcomes
- Radiation Dose and Imaging
- Community Health and Development
- Herpesvirus Infections and Treatments
- Cytomegalovirus and herpesvirus research
- Schizophrenia research and treatment
University of Pittsburgh
2022-2025
Pittsburg State University
2024
University of New Mexico
2014-2023
University of California, San Francisco
2023
Vanderbilt University
2023
Radiology Associates of Albuquerque
2019
General Department of Preventive Medicine
2017
University of New Mexico Hospital
2014
Cdc42 (cell division control protein 42) and Rac1 (Ras-related C3 botulinum toxin substrate 1) are attractive therapeutic targets in ovarian cancer based on established importance tumor cell migration, adhesion, invasion. Despite a predicted benefit, targeting GTPases has not yet been translated to clinical practice. We previously that constitutively active Rac1b overexpressed primary tissues. Through high-throughput screening computational shape homology approaches, we identified...
This article demonstrates how digital information and communication technologies (ICTs) (Zoom/WhatsApp) unexpectedly counterintuitively proved to be valuable tools for community-engaged health research when, in the context of COVID-19 pandemic, they were integrated into a study testing peer support group intervention with female immigrants from Mexico. Because pandemic restrictions, we changed protocol hold meetings remotely via Zoom rather than person as originally planned. recognized that...
IMPORTANCE Hepatitis C virus (HCV) reinfection after curative treatment remains a concern for people who inject drugs. OBJECTIVE To assess the incidence of HCV and associated risk factors. DESIGN, SETTING, AND PARTICIPANTS This cohort study is secondary analysis randomized clinical trial that was conducted across opioid programs community health centers in US between September 2016 August 2018. The current analyses were performed March 2022. People drugs achieved sustained virologic response...
Abstract Using the Cascade of Care framework, we explored demographic and clinical characteristics students at six stages in an early psychosis detection program a college counseling center, with focus on transition between highest disengagement. We detailed compared those who (1) completed Prodromal Questionnaire-Brief (PQ-B, N = 1588); (2) met PQ-B cutoff score (n 486); (3) were referred for secondary phone screening 404); (4) 198); (5) Coordinated Specialty (CSC) eligibility assessment...
<title>Abstract</title> The Clinical Outcomes of Dolutegravir Treatment in People Living with HIV Brazil (CODE) cohort study is a multicenter, prospective, observational designed to evaluate the safety and efficacy (DTG)-based antiretroviral therapy (ART) among people living across diverse settings Brazil. With recent global shift towards DTG as preferred option for first-line ART, particularly low- middle-income countries, there vital need comprehensive real-world data inform its widespread...
Prolonged untreated psychosis worsens outcomes, thus motivating the study of pathways and perceived barriers to care, especially for high-risk age groups like college students. The primary objective this was explore coordinated specialty care (CSC) in students at high risk or with first-episode determine any association between them. Twenty-four enrolled CSC completed Circumstances Onset Relapse Schedule Barriers Seeking Psychological Help Scale (BSPHS). Non-parametric tests were used...
Object Patients with mild traumatic brain injury (mTBI) only rarely need neurosurgical intervention; however, there is a subset of patients whose condition will deteriorate. Given the high resource utilization required for interhospital transfer and relative infrequency intervention, this study was undertaken to determine how often who were transferred intervention if factors that could predict need. Methods The authors performed retrospective review cases involving University New Mexico...
With the ubiquity of digital radiographs, use templating for arthroplasty has become commonplace. Although improved accuracy with radiographs and magnification markers is assumed, it not been shown.We wanted to (1) evaluate in estimating true hip (2) determine if improves on older techniques assuming a 20% all patients.Between April 2013 September we collected 100 AP pelvis patients who had THA prosthesis situ marker placed per manufacturer's instructions. Radiographs seen during our...
Rho family GTPases (including Rac, and Cdc42) collectively control cell proliferation, adhesion migration are of interest as functional therapeutic targets in numerous epithelial cancers. Based on high throughput screening the Prestwick Chemical Library® cheminformatics we identified R-enantiomers two approved drugs (naproxen ketorolac) inhibitors Rac1 Cdc42. The corresponding S-enantiomers considered active component racemic drug formulations, acting non-steroidal anti-inflammatory (NSAIDs)...
Abstract In a post-hoc analysis of the association CMV DNAemia with long-term mortality in randomized trial preemptive therapy vs. antiviral prophylaxis D+R- liver transplant recipients, post-intervention was associated increased after adjusting for study arm.
Abstract The reported incidence of post‐allogeneic HSCT AIHA was between 4.4% and 6% following a single transplant. Cord blood transplantation, T‐cell depletion, chronic G v HD are significantly associated with post‐transplant . During an 11‐yr period, data for 500 pediatric recipients were eligible evaluation the post‐first post‐second transplants. Demographic, transplant, post‐transplant‐related variables analyzed. Twelve (2.4%) at median 273 days seven 72 (9.7%) 157 developed ,...
Abstract Background A quarter of pregnant women use alcohol, 6.5/1000 deliveries are affected by opioid disorder (OUD), and the prevalence cannabis in is increasing. However, marijuana co-exposure polysubstance-using not well described. Methods The well-characterized ENRICH-1 cohort (n = 251), which focused on effects two primary exposures interest—opioids was used to (1) estimate prevalence/frequency those with OUD and/or alcohol use, (2) examined correlates use. Participants were...
We present a method to reintroduce ophthalmic training into the medical school curriculum.To evaluate knowledge and skills acquired when participating in service project, Community Vision Project, develop quantitative for testing with direct ophthalmoscope patients.Second-year students participated study. After 1 month, their was compared that of peers graduates (internal medicine residents). Also at were those upperclassmen who had completed all core clerkships. One year later, after...
Both ventricular and parenchymal devices are available for measurement of intracranial pressure (ICP). The Hummingbird® Synergy Ventricular System is a novel device allowing multi-parametric neurological monitoring, including both ICP. purpose this study to compare the congruence device's ICP readings. This single-center, quantitative, interventional compared readings from 35 patients with System. If difference > ± 3 mmHg existed between an individual patient's values, progressive...
Abstract Background Hospitalization presents an opportunity to begin people with opioid use disorder (OUD) on medications for (MOUD) and link them care after discharge; regrettably, admitted the hospital underlying OUD typically do not receive MOUD are connected subsequent treatment their condition. To address this gap, we launched a multi-site randomized controlled trial test effectiveness of hospital-based addiction consultation team (the Substance Use Treatment Recovery Team (START))...