A5057999162- Fatty Acid Research and Health
- Maternal and Perinatal Health Interventions
- Birth, Development, and Health
- Neonatal Respiratory Health Research
- Pregnancy and preeclampsia studies
- Maternal and fetal healthcare
- Pregnancy-related medical research
- Maternal Mental Health During Pregnancy and Postpartum
- Preterm Birth and Chorioamnionitis
- Gestational Diabetes Research and Management
- Reproductive Health and Contraception
- Adipose Tissue and Metabolism
- Neonatal and fetal brain pathology
- Pregnancy and Medication Impact
- Metabolism and Genetic Disorders
- Cardiovascular Issues in Pregnancy
- Eicosanoids and Hypertension Pharmacology
- Neuroscience of respiration and sleep
- Infant Development and Preterm Care
- Prenatal Substance Exposure Effects
- Male Breast Health Studies
- Clinical practice guidelines implementation
- Assisted Reproductive Technology and Twin Pregnancy
- Metabolomics and Mass Spectrometry Studies
- Employment and Welfare Studies
University of New Mexico
2014-2023
University of Michigan
2004-2019
Women's Hospital
2019
Wright State University
2015
Christiana Care Health System
2015
Cincinnati Children's Hospital Medical Center
2015
Coombe Women & Infants University Hospital
2015
University of Miami
2015
Royal College of Surgeons in Ireland
2015
Medical University of South Carolina
2015
Analysis of n3 fatty acids in serum samples has clinical applications supplementation trials, but the analysis can be challenging due to low levels, stability issues and intra-individual variation. This study presents single laboratory validation a gas chromatographic-mass spectral (GC-MS) assay for acid methyl esters (FAME) using sensitive ion monitoring provides data on under different sample handling conditions. Recovery total from with Folch extraction was optimized parallelism tests...
Vitamin D insufficiency may be associated with depressive symptoms in non-pregnant adults. We performed this study to evaluate whether low maternal vitamin levels are pregnancy. This was a secondary analysis of randomized trial designed assess prenatal omega-3 fatty acid supplementation would prevent symptoms. Pregnant women from Michigan who were at risk for depression based on Edinburgh Postnatal Depression Scale Score or history enrolled. Participants completed the Beck Inventory (BDI)...
The omega-3 fatty acids docosahexaenoic acid (DHA) and eicosapentaenoic (EPA) are precursors to immune regulatory specialized pro-resolving mediators (SPM) of inflammation termed resolvins, maresins, protections. Evidence for lipid mediator formation in vivo can be gained through evaluation their 5-lipoxygenase (LOX) 15-LOX metabolic pathway downstream metabolites: We performed a secondary blood sample analysis from 60 participants the Mothers, Omega-3, Mental Health study determine whether...
This study sought to identify delivery complications associated with stillbirth labour and delivery. We conducted a retrospective chart review evaluating demographics, pregnancy maternal risk factors, of performed bivariable analysis multivariable logistic regression evaluate factors medical variations by race. Our cohort included 543 mothers stillbirth, which two-thirds were African-American. noted high rates shoulder dystocia, clinical chorioamnionitis, postpartum haemorrhage retained...
<b><i>Background:</i></b> In neonatal rats, early post-hypoxia-ischemia (HI) administration of the omega-3 fatty acid docosahexaenoic (DHA) improves sensorimotor function, but does not attenuate brain damage. <b><i>Objective:</i></b> To determine if DHA in addition to hypothermia, now standard care for asphyxial injury, attenuates post-HI damage and deficits. <b><i>Methods:</i></b> Seven-day-old (P7) rats underwent right...
The Royal College of Obstetricians and Gynaecologists (RCOG) defines fetal growth restriction as ultrasound-estimated weight less than the 10th percentile or abdominal circumference percentile; American Gynecologists (ACOG) estimated alone. We compared each method's ability to predict small for gestational age (SGA) at birth.For this retrospective study diagnostic accuracy, we reviewed deliveries University New Mexico Hospital from January 1, 2013, March 31, 2017. included mothers with...
Investigators have hypothesized that omega-3 fatty acid supplementation may modulate the immune response. However, available evidence is conflicting. We performed this study to investigate effect of prenatal eicosapentaenoic (EPA)- and docosahexaenoic (DHA)-rich fish oil on maternal fetal cytokine production. This a secondary analysis randomized controlled trial designed assess whether EPA- or DHA-rich would prevent perinatal depressive symptoms among women at risk. Enrolled participants...
Major depressive disorder (MDD) during pregnancy and postpartum depression are associated with significant maternal neonatal morbidity. While antidepressants readily used in pregnancy, studies have raised concerns regarding neurobehavioral outcomes exposed infants. Omega-3 fatty acid supplementation, most frequently from fish oil, has emerged as a possible treatment or prevention strategy for MDD non-pregnant individuals, may beneficial effects pregnant women. Although published...