- Marriage and Sexual Relationships
- Diet and metabolism studies
- Nutritional Studies and Diet
- Statistical Distribution Estimation and Applications
- Colorectal Cancer Treatments and Studies
- Gut microbiota and health
- Fatty Acid Research and Health
- Statistical Methods and Bayesian Inference
- Sexual function and dysfunction studies
- Advanced Breast Cancer Therapies
- Reliability and Maintenance Optimization
- Colorectal Cancer Screening and Detection
- Probabilistic and Robust Engineering Design
- Inflammatory mediators and NSAID effects
- Obesity, Physical Activity, Diet
- Ginger and Zingiberaceae research
- Cancer, Lipids, and Metabolism
- Statistical Methods and Inference
- Dialysis and Renal Disease Management
- Cervical Cancer and HPV Research
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Musculoskeletal pain and rehabilitation
- Mobile Health and mHealth Applications
- Nutrition and Health in Aging
- Eicosanoids and Hypertension Pharmacology
University of Michigan–Ann Arbor
2016-2025
Michigan United
2013-2024
Wayne State University
2024
Oakland University
1996-2023
Michigan Medicine
2008-2023
Creative Commons
2021
Jackson College
2021
Arbor Research Collaborative for Health
2021
M.C. Townsend Associates (United States)
2021
American College of Preventive Medicine
2014-2019
Abstract – This paper describes early findings of evaluations the International Caries Detection and Assessment System (ICDAS) conducted by Detroit Center for Research on Oral Health Disparities (DCR‐OHD). The lack consistency among contemporary criteria systems limits comparability outcomes measured in epidemiological clinical studies. ICDAS were developed an international team caries researchers to integrate several new into one standard system detection assessment. Using DCR‐OHD cohort...
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Resveratrol, a naturally occurring polyphenol, has cancer chemopreventive properties in preclinical models. It been shown to downregulate the levels of insulin-like growth factor-1 (IGF-I) rodents. The purpose study was assess its safety, pharmacokinetics, and effects on circulating IGF-I IGF-binding protein-3 (IGFBP-3) after repeated dosing. Forty healthy volunteers ingested resveratrol at 0.5, 1.0, 2.5, or 5.0 g daily for 29 days. Levels metabolites were measured by high performance liquid...
Central pain augmentation resulting from enhanced excitatory and/or decreased inhibitory neurotransmission is a proposed mechanism underlying the pathophysiology of functional syndromes such as fibromyalgia (FM). Multiple magnetic resonance imaging studies implicate insula region heightened neuronal activity in this condition. Since glutamate (Glu) major cortical neurotransmitter that functions neurotransmission, we undertook study to test our hypothesis increased levels insular Glu would be...
Approximately half of American adults do not meet recommended physical activity guidelines. Face-to-face lifestyle interventions improve health outcomes but are unlikely to yield population-level improvements because they can be difficult disseminate, expensive maintain, and inconvenient for the recipient. In contrast, Internet-based behavior change disseminated widely at a lower cost. However, impact some Internet-mediated programs is limited by high attrition rates. Online communities that...
Abstract Objective To compare the momentary association between salivary cortisol levels and pain, fatigue, stress symptoms in patients with fibromyalgia (FM), to diurnal cycles of secretion FM healthy control subjects a naturalistic environment. Methods Twenty‐eight 27 completed assessments on symptoms, 5 times day for 2 consecutive days, while engaging usual daily activities. Only those participants who adhered protocol (assessed via activity monitor) were included final analyses. Results...
Abstract Background Studies in K-12 and college students show that their learning preferences have been strongly shaped by new media technologies like video games, virtual reality environments, the Internet, social networks. However, there is no known research on medical students' game experiences or attitudes towards education. This investigation seeks to elucidate student attitudes, see whether they warrant development of teaching methods medicine. Methods Medical from two American...
Communication and language barriers isolate Deaf American Sign Language (ASL) users from mass media, health care messages, communication, which, when coupled with social marginalization, places them at a high risk for inadequate literacy. Our objectives were to translate, adapt, develop an accessible literacy instrument in ASL assess the prevalence correlates of among hearing English speakers using cross-sectional design. A total 405 participants (166 239 hearing) enrolled study. The Newest...
Summary Background and objectives Recommendations to decrease the dialysate sodium (DNa) prescription demand analyses of patient outcomes. We analyzed morbidity mortality at various levels DNa, simultaneously accounting for interdialytic weight gain (IDWG) risk associated with lower predialysis serum (SNa) levels. Design, setting, participants, & measurements used multiply-adjusted linear mixed models evaluate magnitude IDWG Cox proportional hazards assess hospitalizations deaths in...
Perinatal loss is often a traumatic outcome for families. While there are limited data about depressive outcomes in small populations, information depression and posttraumatic stress disorder among large racially economically diverse populations sparse.We collaborated with the Michigan Department of Community Health to conduct longitudinal survey bereaved mothers stillbirth or infant death under 28 days life live-birth (control) Michigan. The study assessed 9-month mental health including...
Background and objectives Hyperuricemia is associated with hypertension, coronary artery disease, chronic kidney disease. However, there are no specific data on the relationship of uric acid to cardiovascular disease in hemodialysis setting. Design, setting, participants, & measurements Data from 5827 patients six countries affiliated Dialysis Outcomes Practice Patterns Study (DOPPS) were analyzed. All laboratory based upon initial cross-section DOPPS I II. Cox regression was used calculate...
The goal was to evaluate marriage and cohabitation outcomes for couples who experienced a live birth or fetal death at any gestational age.For married cohabitating women births, miscarriages, stillbirths, we conducted survival analysis (median follow-up period: 7.8 years), by using data from the National Survey of Family Growth, examine association between subsequent relationship survival. Cox proportional-hazards models controlled multiple independent risk factors known affect outcomes....
We wanted to determine the impact of automated family history assessment and tailored messages for coronary heart disease, stroke, diabetes, colorectal, breast, ovarian cancer on preventive behaviors compared with a standard message.The study was cluster-randomized clinical trial that included 41 primary care practices, majority in Midwest, using Family Healthware, self-administered, Web-based tool assesses familial risk diseases provides personalized risk-tailored messages. Patients control...
To estimate the relationship among presence of vulvodynia, fibromyalgia, interstitial cystitis, and irritable bowel syndrome.Validated questionnaire-based screening tests for four pain conditions were completed by women with without vulvodynia who participating in Michigan Woman to Health Study, a longitudinal population-based survey southeastern Michigan. Weighted estimates prevalence characteristics participants these chronic comorbid calculated using regression analyses.Of 1,940...
Abstract Because of multiple comorbidities, hemodialysis ( HD ) patients are prescribed many oral medications, including phosphate binders PBs ), often resulting in a high “pill burden.” Using data from the international D ialysis O utcomes and P ractice atterns S tudy DOPPS we assessed associations between PB pill burden, patient‐reported non‐adherence, levels serum phosphorus SP hos) parathyroid hormone PTH using standard regression analyses. The study included collected 5262 dialysis...