- Insect and Pesticide Research
- Plant Toxicity and Pharmacological Properties
- Porphyrin Metabolism and Disorders
- Forensic Entomology and Diptera Studies
- Genetic and phenotypic traits in livestock
- Helminth infection and control
- Plant and fungal interactions
- Microbial infections and disease research
- Heme Oxygenase-1 and Carbon Monoxide
- Animal Genetics and Reproduction
- Botanical Research and Chemistry
- Folate and B Vitamins Research
- Trace Elements in Health
- Infectious Diseases and Mycology
- Palliative and Oncologic Care
- Vector-Borne Animal Diseases
- Insect Pest Control Strategies
- Veterinary Oncology Research
- Palliative Care and End-of-Life Issues
- Genetic Mapping and Diversity in Plants and Animals
- Iron Metabolism and Disorders
- Advanced Glycation End Products research
- Biochemical effects in animals
- Bone Metabolism and Diseases
- Patient Dignity and Privacy
Ministerio de Ganadería Agricultura y Pesca
2018-2025
University of New Mexico
2025
Instituto Nacional de Investigación Agropecuaria
2023
Australia and New Zealand Banking Group
2023
Universidade Cruzeiro do Sul
2005-2021
Gran Telescopio Canarias (Spain)
2018
Hospital Moinhos de Vento
2017
Universidad de Montevideo
2016
Universidad de la República
2016
Universidade de São Paulo
2001-2008
Leptospirosis is a neglected zoonosis with worldwide distribution. The causative agents are spirochete bacteria of the Leptospira genus, displaying huge diversity serovars, identity which critical for effective diagnosis and vaccination purposes. Among many other mammalian species, infects cattle, eliciting acute signs in calves, chronic disease adult animals often leading to abortions. In South America, including Uruguay, beef dairy export sources national income. Despite importance bovine...
Intoxication of sheep and cattle by Astylus atromaculatus recently occurred in Uruguay Argentina association with severe drought. Although the disease was experimentally reproduced 1970s, there is limited information on clinical pathologic findings intoxicated this beetle. Here, we described clinical, gross, microscopic 3 orally dosed A. (treatment group, TG) 2 control (control CG) distilled water. Anorexia, lethargy, ruminal stasis, reluctance to move, prolonged recumbency, bruxism were...
<title>Abstract</title> The Clinical Outcomes of Dolutegravir Treatment in People Living with HIV Brazil (CODE) cohort study is a multicenter, prospective, observational designed to evaluate the safety and efficacy (DTG)-based antiretroviral therapy (ART) among people living across diverse settings Brazil. With recent global shift towards DTG as preferred option for first-line ART, particularly low- middle-income countries, there vital need comprehensive real-world data inform its widespread...
The objective of the present study was to test hypothesis that parturition duration is related birth asphyxia in lambs and affects newborn lamb viability vigor. Two sire dam genotypes (Texel: TX; Polwarth: PW) their crosses were represented study. Eighty (25 PW × dam, 13 TX TX, 25 PW, 17 TX) born 69 grazing ewes used. At birth, log₁₀ length second stage parturition, weight, placental several body measurements recorded on all lambs, jugular blood samples analyzed with i-Stat Portable Clinical...
In the summer of 2023, ingestion
Astylus atromaculatus Blanchard is a native beetle of South America that feeds on pollen. During the summer 2022–2023 in Argentina and Uruguay, an explosive infestation these insects occurred pastures which ruminants were grazing. This was believed to be associated with severe drought, had significantly reduced flowering crops. Three farms Uruguay one visited examine flocks perform autopsies. Affected sheep watery diarrhea, anorexia, depression, ruminal atony. The average morbidity,...
Objective To identify and describe the occurrence of neurological lesions that could have an effect on lamb mortality. Procedure The central nervous system was investigated macroscopically (n = 92) microscopically 72) in lambs dying perinatal period during 3 years flocks adult Corriedale ewes. removed intact samples cerebral cortex, basal ganglia, thalamus, hippocampus, mesencephalon, cerebellar medulla oblongata, cervical spinal cord were scored for severity neuronal dead, cytotoxic...
Aminoacetone (AA), triose phosphates, and acetone are putative endogenous sources of potentially cytotoxic genotoxic methylglyoxal (MG), which has been reported to be augmented in the plasma diabetic patients. In these patients, accumulation MG derived from aminoacetone, a threonine glycine catabolite, is inferred observed concomitant endothelial overexpression circulating semicarbazide-sensitive amine oxidases. These copper-dependent enzymes catalyze oxidation primary amines, such as AA...
Clostridium haemolyticum causes bacillary hemoglobinuria (BH), an infectious and usually fatal disease that occurs mostly in cattle, which is clinically characterized by jaundice, hemoglobinuria, anemia. The trematode Fasciola hepatica has been commonly reported as the main predisposing factor triggers this condition. authors evaluated 20 naturally occurring cases of bovine BH to characterize pathology pathogenesis disease. Grossly, most consistent finding was a large, frequently single...
Resumo O testamento vital é tema discutido no âmbito da saúde e do direito, importante instrumento para direcionar a assistência prestada ao paciente terminal de acordo com suas aspirações. Esta pesquisa exploratória abordagem qualitativa estuda opinião 36 médicos, residentes em hospital público, acerca inserção das diretivas antecipadas vontade ou na prática médica. A coleta dados ocorreu agosto 2013. Evidenciou-se relevância respeito à autonomia terminal, propiciando humanização seu...
A disease named locally as churrío or churrido equino (i.e., equine scours) has occurred for at least 100 years in Uruguay and southern Brazil farms along both shores of the Merín lake. This report describes cases provides serologic, pathologic, DNA-based evidence indicating that is fact monocytic ehrlichiosis (Potomac horse fever). Results an epidemiological investigation conducted on endemic farm are also presented. Clinical signs 12 horses were fever, depression, diarrhea, dehydration,...
Aminoacetone (AA) is a threonine and glycine catabolite long known to accumulate in cri-du-chat threoninemia syndromes and, more recently, implicated as contributing source of methylglyoxal (MG) diabetes mellitus. Oxidation AA MG, NH4+, H2O2 has been reported be catalyzed by copper-dependent semicarbazide sensitive amine oxidase (SSAO) well Cu(II) ions. We here study the mechanism aerobic oxidation, presence absence iron ions, coupled release from ferritin. (1−7 mM) autoxidizes...
Astylus atromaculatus is a pollen beetle native to South America, commonly found in crop flowers. Experimental intoxication of sheep and guinea pigs by this resulting fibrinonecrotizing enteritis has been reported. We describe here 6 natural outbreaks cattle associated with consumption alfalfa (5 6) mixed (1 pastures heavily contaminated A. atromaculatus. The occurred during the summer (January–February) 2023 Argentina ( n = 4) Uruguay 2), beef under extensive or semi-extensive rearing...
ABSTRACT: Equine pythiosis is an ulcerative and granulomatous disease of the skin, caused by oomycete Pythium insidiosum (Pythiaceae). The objective this study was to describe seven cases equine that occurred from 2012 2017 in eastern region Uruguay. Six wetland ecosystems Merin basin, remaining case fluvial plains Tacuarembó River. Lesions consisted a large, rapidly growing ulcerated tumor with abundant granulation tissue, serosanguineous secretion, fistulous tracts containing large...
In the present study, right hind limb bones from 46 12‐month‐old bulls with no clinical signs were examined to identify and describe lesions that could predispose stifle tarsal joints osteoarthritis. The came a performance testing station slaughtered due low index at end of period 1996–97. Differences in frequency among breeds as well relationship between growth rate evaluated. Forty‐five (97.8 %) had and/or plates. Prevalence was 100 % Charolais (22/22), Hereford (8/8), Limousin (4/4)...
Aminoacetone (AA), a putative endogenous source of cytotoxic methylglyoxal, and ceruloplasmin (CP), the antioxidant plasma copper transporter, are known to increase in diabetes. AA was recently shown vitro act as pro-oxidant toward ferritin isolated mitochondria. We now report oxidative effects on CP mediated by AA-generated reactive oxygen species (ROS). Incubation 1.5 μM human with 0.05−1 mM resulted extensive protein aggregation. That ROS-driven thiol cross-linking underlies aggregation...