A5084788731- Hepatitis C virus research
- Hepatitis B Virus Studies
- Liver Disease Diagnosis and Treatment
- HIV/AIDS drug development and treatment
- Education during COVID-19 pandemic
- HIV/AIDS Research and Interventions
- Systemic Lupus Erythematosus Research
- HIV-related health complications and treatments
- Cervical Cancer and HPV Research
- Vector-Borne Animal Diseases
- COVID-19 Clinical Research Studies
- HIV Research and Treatment
- HIV/AIDS oral health manifestations
- Healthcare Regulation
- SARS-CoV-2 and COVID-19 Research
- T-cell and Retrovirus Studies
- COVID-19 and Mental Health
- Animal Disease Management and Epidemiology
- Education and Public Policy
- Syphilis Diagnosis and Treatment
- Leprosy Research and Treatment
- Antifungal resistance and susceptibility
- Fungal Infections and Studies
- COVID-19 Impact on Reproduction
- Science and Education Research
Universidade Federal do Espírito Santo
2010-2025
Universidade de São Paulo
2017-2023
Universidade Federal do Rio de Janeiro
2017
Hospital Federal dos Servidores do Estado
2017
Universidade Federal de São Paulo
2017
Universidade de Ribeirão Preto
2017
<title>Abstract</title> The Clinical Outcomes of Dolutegravir Treatment in People Living with HIV Brazil (CODE) cohort study is a multicenter, prospective, observational designed to evaluate the safety and efficacy (DTG)-based antiretroviral therapy (ART) among people living across diverse settings Brazil. With recent global shift towards DTG as preferred option for first-line ART, particularly low- middle-income countries, there vital need comprehensive real-world data inform its widespread...
Introdução: A infecção pelo vírus da imunodeficiência humana (HIV) ainda é um relevante problema de saúde pública. Embora a maioria dos casos esteja concentrada na população mais jovem, faixa etária acima 50 anos está em ascensão. Objetivo: Descrever o perfil clínico e epidemiológico pacientes idosos infectados por HIV/aids era pós-HAART acompanhados centro referência. Métodos: Este estudo epidemiológico, retrospectivo, qualiquantitativo realizado no ambulatório do Serviço Infectologia...
Background Human T cell lymphotropic virus type 1 (HTLV-1) is highly endemic in Brazil, necessitating surveillance studies to understand its epidemiology. While previous research has focused on either specific cities or populations, there a need for multicenter encompassing epidemiologically relevant populations ascertain more accurate prevalence rates and predictors of HTLV-1 infection the country. Methods We conducted multicenter, cross-sectional study involving 3,184 participants across...
Both leprosy and human immunodeficiency virus (HIV) are infectious diseases, an important global health problem. Patients with who co‐infected HIV seem to be at higher risk of developing reactions. To examine the histological features in patients co‐infection, particularly determine whether typical histopathology is present skin biopsies, assess reactions patients. This was a matched cohort study 11 31 HIV‐negative leprosy. A structured protocol for skin‐biopsy evaluation followed, focusing...
Abstract BACKGROUND COVID-19 is affecting almost the entire world, causing more than four hundred thousand deaths and undermining health care systems, as much economy, of afflicted countries. The strategies for prevention depend on largely lacking information, infection prevalence virus pathogenicity. This study aimed to determine prevalence, pathogenicity, speed spreading in a large population Brazil. MATERIALS AND METHODS serial cross-sectional designed basis structured over houses...
Twelve cases of histoplasmosis in HIV-infected patients were found a retrospective analysis at the Hospital Universitário Cassiano Antônio de Moraes Universidade Federal do Espírito Santo (HUCAM), Vitória (ES), from June 1999 to May 2001. The frequency among HIV-positive was 2.1% infectious diseases division hospital during this period. Histoplasmosis compromised mainly males (11/12), 27 44 years old, and residents metropolitan urban area (10/12). Alcohol abuse tobacco smoking described 10...
Espírito Santo state is considered a region with higher frequency of hepatitis B virus infection. This study characterized demographic, epidemiological, laboratory, virological and clinical aspects 587 chronic HBV carriers followed up at the University Hospital.Demographic, laboratory data were extracted from medical records during entire follow-up period. Classification evolutionary phases was defined as immunotolerant; inactive carrier; active HBeAg (+) (-). Characterization...
Introduction: Women living with HIV/AIDS have a higher frequency of anogenital neoplasms resulting from human papillomavirus (HPV) infection. The World Health Organization recommends that cervical cancer screening uses molecular tests amplify viral genetic material, such as HPV-DNA. In addition to collection by health professionals, self-collection vaginal samples is useful tool for expanding access testing. Objective: To describe the results pilot study evaluated acceptability and...
Resumo Objetivo: Analisar aspectos sociodemográficos e clínicos autorreferidos entre indivíduos de 2 a 22 anos idade possíveis associações com infecção por SARS-CoV-2 no Espírito Santo, Brasil. Métodos: Estudo transversal seriado base populacional, realizado maio junho 2020. Avaliou-se o percentual positividade para COVID-19, teste sorológico, os fatores associados pelo qui-quadrado Pearson (nível significância 5%). Resultados: Entre 1.693 anos, 6,1% apresentaram positivo COVID-19; destes,...
Infection by hepatitis C virus is one of the leading causes chronic and cause severe burden for patients, families health care system.The aims this research were to assess severity liver fibrosis, comorbidities complications virus; examine health-related quality life (HRQoL), productivity loss resource use costs in a sample Brazilian C, genotype 1, patients.This was cross-sectional multicenter study performed genotype-1 patients disease public system between November 2014 March 2015....
Glecaprevir/pibrentasvir is a highly effective and well tolerated treatment for hepatitis C infection. Brazilian patients were not included in the original development studies glecaprevir/pibrentasvir. This study aimed to assess safety efficacy of glecaprevir/pibrentasvir treatment-naïve adults without cirrhosis or with compensated cirrhosis. EXPEDITION-3 was Phase 3, open-label, multicenter infection genotype 1–6. Patients (F2 F3) (F4) received 8 12 weeks glecaprevir/pibrentasvir,...
OBJECTIVE:To evaluate the effectiveness and safety of first-generation protease inhibitors for treatment genotype 1 hepatitis C virus-infected patients at Brazilian reference centers.METHODS: This multicenter cross-sectional study included virus monoinfected treated with Peg-interferon, ribavirin, either boceprevir (n=158) or telaprevir (n=557) between July 2013 April 2014 15 centers in Brazil.Demographic, clinical, virological, adverse events data were collected during follow-up.RESULTS: Of...
in Brazil, chronic hepatitis C patients coinfected with the human immunodeficiency virus (HIV) is treated pegylated interferon (Peg-IFN) and ribavirin (RBV). However, few studies have evaluated effectiveness of this treatment particular population. The identification factors that predict sustained virological response (SVR) under current clinical practice would enable clinicians to more accurately estimate probability achieving an SVR therefore utilize appropriate therapeutics, especially...
to estimate the prevalence of SARS-CoV-2 infection in residents Greater Vitória region living subnormal and non-subnormal agglomerates, compare sociodemographic clinical characteristics total (infected not infected with SARS-CoV-2) between them.Population-based study conducted by serological testing 2020, a unit households Vitória, grouped into census tracts classified as sub-normal agglomerates non-sub-normal agglomerates. The two groups were compared terms associated factors. significance...
Despite recent advances in therapy for chronic hepatitis C (CHC), the disease caused by genotype 3 virus (GEN3) is still considered a treatment challenge certain patient subgroups. The aim of this retrospective study was to evaluate effectiveness and safety peginterferon (Peg-IFN) ribavirin (RBV) combination GEN3/CHC patients, sustained virological response (SVR) indicators early interruption due serious adverse events (SAE). This observational co-infected or not HIV treated with Peg-IFN/RBV...
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Background: Women living with human immunodeficiency virus (HIV) (WLWH) are more likely to be infected the oncogenic papillomavirus (HPV). We assessed prevalence of high-risk (HR) (16/18/31/33/35/39/45/51/52/56/58/59/68/73/82), probable (pHR) (26/53/66), and low-risk (LR) (6/11/40/42/43/44/54/61/70) HPV types their associated risk factors. Methods: This cross-sectional study WLWH aged 18-64 years included one laboratory eight HIV-specialty healthcare facilities in pilot network. Descriptive...
Resumo Objetivo: Analisar a soroprevalência de SARS-CoV-2 e sua associação com aspectos sociodemográficos clínicos, no estado do Espírito Santo, Brasil. Métodos: Estudo transversal seriado, realizado em quatro fases, período maio junho 2020, utilizando os domicílios como unidade análise. Foram pesquisados 11 municípios, amostra 4.500 cada fase. Resultados: A variou 2,1% (IC95% 1,7;2,5), 10 (primeira etapa), 9,6% 8,8;10,4) 21 (quarta etapa). Na Região Metropolitana da Grande Vitória, as...