A5001219573- Traumatic Brain Injury and Neurovascular Disturbances
- Neurosurgical Procedures and Complications
- Intracerebral and Subarachnoid Hemorrhage Research
- Spinal Fractures and Fixation Techniques
- Diversity and Career in Medicine
- Trauma and Emergency Care Studies
- Meningioma and schwannoma management
- Traumatic Brain Injury Research
- Surgical Simulation and Training
- Spine and Intervertebral Disc Pathology
- Innovations in Medical Education
- Cardiac Arrest and Resuscitation
- Head and Neck Surgical Oncology
- Spinal Hematomas and Complications
- Neurofibromatosis and Schwannoma Cases
- Respiratory Support and Mechanisms
- Healthcare professionals’ stress and burnout
- Pelvic and Acetabular Injuries
- Traumatic Ocular and Foreign Body Injuries
- Radiation Dose and Imaging
- Management of metastatic bone disease
- History of Medical Practice
- Musculoskeletal pain and rehabilitation
- Atrial Fibrillation Management and Outcomes
- Global Health and Surgery
Beth Israel Deaconess Medical Center
2016-2025
Harvard University
2016-2025
Collaborative Research Group
2022
Beth Israel Deaconess Hospital
2021
Hadassah Medical Center
2016-2020
Oxford University Press (United Kingdom)
2020
Northwell Health
2019
University of California Davis Medical Center
2019
Thomas Jefferson University Hospital
2019
Icahn School of Medicine at Mount Sinai
2019
Cranial base chordomas are difficult lesions to treat. The endoscopic endonasal approach (EEA) takes advantage of the natural sinus corridor and may provide a less invasive for these midline tumors.Patients undergoing EEA were selected from database more than 800 consecutive patients at University Pittsburgh Medical Center retrospectively evaluated. Additionally, systematic review literature endonasally resected was performed compared with our personal experience.Twenty (8 females 12 males)...
Object Current standard of care for patients with severe traumatic brain injury (TBI) is prophylactic treatment phenytoin 7 days to decrease the risk early posttraumatic seizures. Phenytoin alters drug metabolism, induces fever, and requires therapeutic-level monitoring. Alternatively, levetiracetam (Keppra) does not require serum monitoring or have significant pharmacokinetic interactions. In current study, authors compare EEG findings in receiving those monotherapy seizure prophylaxis...
OBJECTIVE Chronic subdural hematoma (CSDH) is commonly encountered in neurosurgical practice. However, surgical evacuation remains complicated by a high rate of reoperation. The optimal approach to reduce the reoperation has not been determined. In current study, authors evaluated prognostic value clinical and radiographic factors predict context CSDH. METHODS A retrospective review 325 CSDH patients admitted an academic medical center United States, between 2006 2016, was performed....
Middle meningeal artery (MMA) embolization is an emerging minimally invasive endovascular technique for chronic subdural hematoma (cSDH). Currently, limited literature exists on its safety and efficacy compared with conventional treatment (open-surgical-evacuation-only).To compare MMA to treatment.Retrospective analysis of patients cSDHs treated in a single center from 2018 2019 was performed. Comparisons were made historical cohort 2006 2016. Propensity score matching used assemble balanced...
The Women in Neurosurgery (WINS) and the American Association of Neurological Surgeons published a white paper 2008 setting an ambitious goal for women to comprise 20% neurosurgery residents by 2012 practicing neurosurgeons 2020. Although there has been steady progress, we have fallen short these benchmarks. We take this opportunity look back at accomplishments made over past decade provide update on our present status. evaluate current barriers toward progress propose new goals,...
INTRODUCTION: Translational and clinical research has demonstrated that an Enriching Environment (EE) can significantly benefit neurologic outcomes of patients with traumatic brain injury (TBI), spinal cord (SCI) or other lesions the CNS. EE been shown to enhance recovery process by promoting neuroplasticity through increased neurostimulation, neurogenesis stress reduction. Therefore, could serve as a viable preclinical model neurorehabilitation adjunct therapy standard post-TBI...
Object Patients with mild traumatic brain injury (mTBI) only rarely need neurosurgical intervention; however, there is a subset of patients whose condition will deteriorate. Given the high resource utilization required for interhospital transfer and relative infrequency intervention, this study was undertaken to determine how often who were transferred intervention if factors that could predict need. Methods The authors performed retrospective review cases involving University New Mexico...
Minimizing secondary brain injuries after traumatic injury (TBI) in children is critical to maximizing neurological outcome. Brain tissue oxygenation monitoring (as measured by interstitial partial pressure of O2 [PbO2]) a new tool that may aid guiding therapies, yet experience limited. This study aims describe the authors' PbO2 TBI. It was hypothesized thresholds could be established were associated with favorable outcome, and it determined whether any relationships between other important...
Olfactory dysfunction (OD) is a disorder associated with traumatic brain injury (TBI), which prevalent in up to 20% of patients suffering from TBI. Nevertheless, most studies focusing on the relationship between OD and TBIs do not differentiate different types TBI (mild, medium, severe). In this paper, we conducted comprehensive systematic review existing literature for association mild (mTBI) order examine their relationship, its neurosurgical management radiographic characteristics.The...
The end of the first 100 years any endeavor is an appropriate time to look back and peer forward. As neurosurgery celebrates its 1st century as a specialty, increasing role women neurosurgeons major theme. This article documents early pioneers in neurosurgery. contributions these trailblazers origins, academics, professional organizations are highlighted. formation Women Neurosurgery 1989 described, important this organization has played introducing promoting talented profession....
Object Despite the application of current standard therapies, vasospasm continues to result in death or major disability patients treated for ruptured aneurysms. The authors investigated effectiveness continous MgSO 4 infusion prophylaxis. Methods Seventy-six adults (mean age 54.6 years; 71% women; 92% Caucasian) were included this comparative matched-cohort study with aneurysmal subarachnoid hemorrhage on basis computed tomography (CT) findings. Thirty-eight who received continuous matched...
We measured quantitative cortical mantle cerebral blood flow (CBF) by stable xenon computed tomography (CT) within the first 12 h after severe traumatic brain injury (TBI) to determine whether neurologic outcome can be predicted CBF stratification early injury. Stable CT was used for measurement of (mL/100 g/min) in 22 regions stratified as follows: low (0-8), intermediate (9-30), normal (31-70), and hyperemic (>70) 120 patients suffering (Glasgow Coma Scale [GCS] score ≤8) TBI. For each...
Penetrating traumatic brain injury (pTBI) affects civilian and military populations resulting in significant morbidity, mortality, healthcare costs. No up-to-date evidence-based guidelines exist to assist modern medical surgical management of these complex injuries. A preliminary literature search revealed a need for updated guidelines, supported by the Brain Trauma Foundation. Methodologists experienced TBI were recruited support project development alongside two cochairs diverse steering...
OBJECTIVE Middle meningeal artery embolization (MMAE) is an emerging endovascular treatment technique with proven promising results for chronic subdural hematomas (cSDHs). MMAE as adjunct to open surgery being utilized the goal of preventing recurrence cSDH. However, efficacy following surgical evacuation cSDH has not been clearly demonstrated. The authors sought compare outcomes followed by versus alone. METHODS Patients who underwent alone (open surgery–alone group) or along (adjunctive...
"Moral distress" describes the psychological strain a provider faces when unable to uphold professional values because of external constraints. Recurrent or intense moral distress risks injury, burnout, and physician attrition but has not been systematically studied among neurosurgeons.
Serum magnesium concentration has a neuroprotective effect in experimental models of traumatic brain injury (TBI). This study was designed to assess the relationship between initial serum magnesium, cerebrospinal fluid (CSF) neurological outcome and efficacy replacement therapy (MgSO4). A retrospective analysis performed on prospectively collected dataset from 216 patients admitted during 1996-2006 University Pittsburgh Medical Center with severe TBI. Admission CSF were dichotomized into low...