A5114357284- Dialysis and Renal Disease Management
- Renal Transplantation Outcomes and Treatments
- Healthcare Policy and Management
- Geriatric Care and Nursing Homes
- Organ Donation and Transplantation
- Health Systems, Economic Evaluations, Quality of Life
- Frailty in Older Adults
- Central Venous Catheters and Hemodialysis
- Restless Legs Syndrome Research
- Nutrition and Health in Aging
- Organ Transplantation Techniques and Outcomes
- Neurological Complications and Syndromes
- Prostate Cancer Treatment and Research
- Sleep and related disorders
- Innovations in Medical Education
- Iron Metabolism and Disorders
- Hemoglobinopathies and Related Disorders
- Sleep and Wakefulness Research
- Parkinson's Disease Mechanisms and Treatments
- Parathyroid Disorders and Treatments
- Cardiac Health and Mental Health
- Vascular Procedures and Complications
- Pregnancy and Medication Impact
- Disaster Response and Management
- Employment and Welfare Studies
University of Pennsylvania
2018-2024
Emory University
2014-2024
Hospital of the University of Pennsylvania
2023
Philadelphia University
2023
IIT@MIT
2021
The University of Queensland
2020
University of Maryland, Baltimore
2020
Massachusetts Institute of Technology
2020
Georgia Department of Public Health
2010-2019
Emory Healthcare
2017
IL-23 is a heterodimeric cytokine composed of the IL-12p40 "soluble receptor" subunit and novel cytokine-like related to IL-12p35, termed p19. Human mouse exhibit some activities similar IL-12, but differ in their capacities stimulate particular populations memory T cells. Like binds IL-12R IL-12Rbeta1. However, it does not use IL-12Rbeta2. In this study, we identify member hemopoietin receptor family as for IL-23, "IL-23R." IL-23R pairs with IL-12Rbeta1 confer responsiveness on cells...
Background At 6 months poststroke, most patients cannot incorporate their affected hand into daily activities, which in turn is likely to reduce perceived quality of life. Objective This preliminary study explored change patient-reported, health-related life associated with robotic-assisted therapy combined reduced therapist-supervised training. Design and Setting A single-blind, multi-site, randomized clinical trial was conducted. Participants Seventeen individuals who were 3 9 poststroke...
Accurate, automated extraction of clinical stroke information from unstructured text has several important applications. ICD-9/10 codes can misclassify ischemic events and do not distinguish acuity or location. Expeditious, accurate data could provide considerable improvement in identifying large datasets, triaging critical reports, quality efforts. In this study, we developed report a comprehensive framework studying the performance simple complex stroke-specific Natural Language Processing...
Background. Non‐compliance with prescribed therapy significantly impacts dialysis patient care and outcomes. The underlying psychosocial issues leading to non‐compliance are not well understood, especially in peritoneal (PD) patients.
Background. It has been suggested that there are no large differences in the quality of life incident patients starting on haemodialysis (HD) and peritoneal dialysis (PD), but few studies have addressed this issue.
The purpose of this study was to identify early patterns care for Alzheimer's disease (AD) in a cohort African-American patients and their caregivers presenting at an inner city clinic suburban memory assessment clinic. Caregivers (N=79) diagnosed with probable AD were interviewed. Data collected about the delay from noticing first signs until recognition that problem existed physician consultation. Patients had lower educational status, been more recently than clinic, although MMSE scores...
The extent to which racial and socioeconomic disparities in access kidney transplantation are related not being assessed for transplant suitability before or shortly after the time of initiation dialysis is known. aims this study were determine whether there based on race, ethnicity, type insurance delayed assessment was associated with lower likelihood waitlisting transplantation.This retrospective cohort used data from US Renal Data System included 426,489 adult patients beginning United...
Although the arteriovenous fistula (AVF) is recommended form of vascular access for patients with ESRD, its impact on patient perception health status, quality life (QOL), or satisfaction unknown.This study compared patient-reported status and QOL scores type among a national random sample 1563 at dialysis initiation day 60 ESRD during 1996 to 1997. Patients were stratified into five categories: AVF first graft (AVG) 60, central venous catheter (CVC) CVC AVG 60.Ten percent (n = 154) had an...
When patients start dialysis, their employment rate declines and disability benefits are an option. With patient sociodemographic clinical characteristics including income status controlled, we investigated the significance of depressed mood usual activity level as predictors patients' continued after dialysis start.
While there have been many solutions proposed for storing and analyzing large volumes of data, all these limited support collaborative data analytics, especially given the individuals teams are simultaneously analyzing, modifying exchanging datasets, employing a number heterogeneous tools or languages analysis, writing scripts to clean, preprocess, query data. We demonstrate DataHub, unified platform with ability load, store, query, collaboratively analyze, interactively visualize, interface...
This population epidemiology study uses US Renal Data System data to characterize emergency department (ED) visits, hospitalizations from the ED, and demographic characteristics of patients with end-stage renal disease who used ED services between 2005 2011.
While SARS-CoV-2 vaccines have shown strong efficacy, the continued emergence of new viral variants raises concerns about ongoing and future public health impact COVID-19, especially in locations with suboptimal vaccination uptake. We investigated host factors, including status, that were associated disease severity a setting low rates. analyzed clinical demographic data from 1,957 individuals state Georgia, USA, coupled genome sequencing 1,185 samples. found no specific mutations severity....
Investigation of factors associated with variation in dialysis patient employment has focused primarily on patient-level factors. Little is known about facility-level that may be employment.The ESRD Facility Survey (CMS-2744A) began 2004 to collect counts employed patients aged 18 54, addition unit census, types and timing treatments offered, staffing. Using the File, we investigated characteristics facility rate 54 a logistic regression analysis included hospital-based chronic renal care...
Few US patients with kidney failure start treatment on peritoneal dialysis (PD) despite its potential survival, quality of life, and cost-saving benefits. We investigated patient awareness PD variables associated selection, including unit ownership geographic area.In a cohort study, incident identified by the Centers for Medicare Medicaid Services (CMS) included in United States Renal Data System (USRDS) were surveyed from 2005 to 2007 USRDS Comprehensive Dialysis Study. Participants...
Abstract Needing assistance with activities of daily living ( ADL ) is an early indicator functional decline and has important implications for individuals' quality life. However, correlates need have received limited attention among patients undergoing maintenance hemodialysis HD ). A multicenter cohort 742 prevalent was assessed in 2009–2011 classified as frail, prefrail nonfrail by the F ried frailty index (recent unintentional weight loss, reported exhaustion, low grip strength, slow...