Takeo Shimizu

ORCID: 0000-0001-7340-7424
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About
Contact & Profiles
Research Areas
  • Intracranial Aneurysms: Treatment and Complications
  • Plant Pathogens and Fungal Diseases
  • Plant and Fungal Interactions Research
  • Horticultural and Viticultural Research
  • Plant Virus Research Studies
  • Vascular Malformations Diagnosis and Treatment
  • Fermentation and Sensory Analysis
  • Plant Disease Management Techniques
  • Plant Disease Resistance and Genetics
  • Microbial Metabolism and Applications
  • Enzyme Production and Characterization
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Plant-Microbe Interactions and Immunity
  • Reproductive Physiology in Livestock
  • Neurosurgical Procedures and Complications
  • Cerebrovascular and Carotid Artery Diseases
  • Cerebrospinal fluid and hydrocephalus
  • Fetal and Pediatric Neurological Disorders
  • Epilepsy research and treatment
  • Legume Nitrogen Fixing Symbiosis
  • Plant Reproductive Biology
  • Powdery Mildew Fungal Diseases
  • Acute Ischemic Stroke Management
  • Botulinum Toxin and Related Neurological Disorders
  • Postharvest Quality and Shelf Life Management

National Agriculture and Food Research Organization
2012-2024

Institute of Fruit Tree and Tea Science
2012-2024

Meiji University
2010-2019

Central Region Agricultural Research Center
2018

Osaka University
2005-2008

Osaka International University
2005

Tohoku University
1978-2002

Mie University
1981-2001

Mie Chuo Medical Center
2001

Shimizu (Japan)
2001

Chitin is a major molecular pattern for various fungi, and its fragments, chitin oligosaccharides, are known to induce defense responses in plant cells. A plasma membrane glycoprotein, CEBiP (chitin elicitor binding protein) receptor kinase, CERK1 kinase) (also as LysM-RLK1), were identified critical components signaling rice Arabidopsis, respectively. However, it not whether each species requires both of these two types molecules signaling, nor the relationships between signaling. We report...

10.1111/j.1365-313x.2010.04324.x article EN other-oa The Plant Journal 2010-08-12

ABSTRACT Citrinin produced by Aspergillus , Penicillium and Monascus species is a polyketide compound that has nephrotoxic activity in mammals bactericidal toward gram-positive bacteria. To avoid the risk of citrinin contamination other fermentation products purpureus knowledge biosynthetic genes needed so citrinin-nonproducing strains can be generated. We cloned synthase (PKS) gene from M. with degenerate primers designed to amplify conserved region ketosynthase domain fungal PKS. A 13-kb...

10.1128/aem.71.7.3453-3457.2005 article EN Applied and Environmental Microbiology 2005-07-01

ABSTRACT Multi-level cervical spondylosis and ossification of the posterior longitudinal ligament (OPLL) are well-documented causes myelopathy. The choice surgical procedures remain controversial. Between January 1983 December 1987, we have performed anterior vertebrectomy in 45 patients with myelopathy caused by multi-level OPLL. They consisted 19 spondylosis, 12 OPLL, 14 combined lesions both There were 32 men 13 women. mean age was 55 years, ranging from 35 to 70 years. In all our...

10.1227/00006123-198906000-00012 article EN Neurosurgery 1989-06-01

A characteristic increase in multiple-unit activity (MUA volley) synchronized with the pulsatile secretion of luteinizing hormone (LH) by pituitary gland was recorded from electrodes chronically implanted medial basal hypothalamus ovariectomized goats. The MUA volley always preceded LH pulse, and temporal correlation consistent even when pulse frequency altered an anesthetic or exogenous steroids. electrophysiological manifestation hypothalamic 'pulse generator' governing...

10.1159/000125746 article EN Neuroendocrinology 1991-01-01

ABSTRACT Citrinin, a secondary fungal metabolite of polyketide origin, is moderately nephrotoxic to vertebrates, including humans. From the red-pigment producer Monascus purpureus , 21-kbp region flanking pksCT which encodes citrinin synthase, was cloned. Four open reading frames (ORFs) ( orf1 orf2 orf3 and orf4 ) in 5′-flanking one ORF orf5 3′-flanking were identified vicinity pksCT. encode homolog dehydrogenase (similarity, 46%), regulator 38%), an oxygenase 41%), oxidoreductase 26%),...

10.1128/aem.01979-06 article EN Applied and Environmental Microbiology 2007-06-23

This study was conducted to estimate the effects of kisspeptin-10 on blood concentrations LH and GH in prepubertal dairy heifers. Heifers received a single injection 1 mg (n=5) or saline intravenously, serial samples were collected at 15-min intervals analyze response curves both after injection. Peak-shaped responses observed for GH, peaks 27+/-3 75+/-9 min, respectively, injection, only heifers injected with kisspeptin-10. These data suggest various possible important links among...

10.1677/joe-07-0504 article EN Journal of Endocrinology 2007-11-19

Lysin motif (LysM) receptor-like kinase CERK1 is a co-receptor essential for plant immune responses against carbohydrate microbe-associated molecular patterns (MAMPs). Concerning the immediate downstream signaling components of CERK1, cytoplasmic kinases such as PBL27 and other RLCK VII members have been reported to regulate positively. In this study, we report that novel CERK1-interacting E3 ubiquitin ligase, PUB4, also involved in regulation MAMP-triggered responses. Knockout PUB4 resulted...

10.1093/pcp/pcz151 article EN Plant and Cell Physiology 2019-07-29

10.1177/00220345640430040201 article EN Journal of Dental Research 1964-07-01

RNA silencing acts as a defense mechanism against virus infection in wide variety of organisms. Here, we investigated inductions encapsidated double-stranded (dsRNA) fungal viruses (mycoviruses), including partitivirus (RnPV1), quadrivirus (RnQV1), victorivirus (RnVV1), mycoreovirus (RnMyRV3), and megabirnavirus (RnMBV1) the phytopathogenic fungus Rosellinia necatrix Expression profiling silencing-related genes revealed that dicer-like gene, an Argonaute-like two RNA-dependent polymerase...

10.1128/jvi.02951-15 article EN Journal of Virology 2016-03-31

Regional cerebral blood flow (rCBF) during controlled hemorrhagic hypotension (140–20 mm Hg) was assessed 10–14 days after chronic unilateral sectioning of parasympathetic and/or sensory fibers innervating pial vessels in spontaneously hypertensive rats (SHR). rCBF measured the cortical barrel fields bilaterally by laser Doppler flowmetry. Immunohistochemistry middle artery (MCA) whole mount preparations used to verify surgical lesion. During hypotension, equivalent on two sides shams,...

10.1038/jcbfm.1992.85 article EN Journal of Cerebral Blood Flow & Metabolism 1992-07-01

Understanding the molecular mechanisms of pathogenesis is useful in developing effective control methods for fungal diseases. The white root rot fungus Rosellinia necatrix a soilborne pathogen that causes serious economic losses various crops, including fruit trees, worldwide. Here, using next-generation sequencing techniques, we first produced 44-Mb draft genome sequence R. strain W97, an isolate from Japan, which 12,444 protein-coding genes were predicted. To survey differentially...

10.1094/phyto-11-17-0365-r article EN other-oa Phytopathology 2018-04-24

Ventriculoperitoneal shunting has been accepted as a safe and useful preliminary procedure that lowers the mortality morbidity of definitive surgery for tumors causing obstructive hydrocephalus. We are reporting four patients with intratumoral hemorrhage complication shunting. The was massive fatal in two patients, one an unverified pineal tumor other malignant astrocytoma thalamus. small limited glioblastoma thalamus cerebellar astrocytoma. On basis this experience, we conclude possibility...

10.1227/00006123-198109000-00005 article EN Neurosurgery 1981-09-01

Background and Purpose —We report the first case of pituitary apoplexy caused by rupture an intracavernous carotid artery aneurysm embedded in a adenoma. Case Description —A 46-year-old man presented with clinical CT findings typical apoplexy. MRI showed unusual flow-void protrusion into intratumoral hematoma, which, however, was not diagnosed as ruptured until severe intraoperative bleeding occurred. Angiography after surgery revealed aneurysm. Conclusions —The possible association adenoma...

10.1161/01.str.32.2.567 article EN Stroke 2001-02-01

Glycoconjugates and glycogen obtained from the cervix uteri of nonpregnant women proliferative phase secretory phase, postpartum were determined by electrophoresis on cellulose acetate membrane chemical analysis before after enzymatic digestion nitrous acid treatment. Although contents neutral glycopeptide fraction in these tissues similar, content tissue greatly decreased. The terms hexosamine hyaluronic acid, chondroitin sulfate, heparan sulfate acidic glycopeptides increased comparison...

10.1620/tjem.131.289 article EN The Tohoku Journal of Experimental Medicine 1980-01-01

Leaf trichomes confer pest resistance. Dense could also present a physical barrier to microorganisms, such as grapevine downy mildew caused by Plasmopara viticola on grape. Zoospores of P. swim in water and enter stomata. Some wild Vitis accessions V. labrusca cinerea have highly hydrophobic, dense, prostrate the lower leaf surface that repel enhance resistance mildew. Quantitative trait loci for trichome density been identified LGs 5, 7, 8, 15 grapevine. A major locus LG 5 was found...

10.6090/jarq.54.293 article EN Japan Agricultural Research Quarterly JARQ 2020-10-01

Gonadotropin-releasing hormone (GnRH) neurons were examined immunohistochemical-ly in the brain of mature female Shiba goats with a monoclonal antibody to GnRH (LRH-13, Park and Wakabayashi, Endocrinol.Jpn. 33: 257-272, 1986). In all animals, immunoreactive exhibited complex morphology consisting round (49.6%), multipolar (39.8%) or fusiform (10.6%) cell bodies fibers beaded varicosities. distributed rostrally from diagonal band Broca medial septum, passing through lateral preoptic areas,...

10.1262/jrd.38.133 article EN Journal of Reproduction and Development 1992-01-01

10.1016/s0278-2391(87)80014-9 article EN Journal of Oral and Maxillofacial Surgery 1987-06-01
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