A5010572149- Botulinum Toxin and Related Neurological Disorders
- Cerebral Palsy and Movement Disorders
- Muscle activation and electromyography studies
- Neurological disorders and treatments
- Stroke Rehabilitation and Recovery
- Nerve Injury and Rehabilitation
- Tendon Structure and Treatment
- Acute Ischemic Stroke Management
- Genetic Neurodegenerative Diseases
- Shoulder Injury and Treatment
- Dental Health and Care Utilization
- Radioactive element chemistry and processing
- Foot and Ankle Surgery
- Neurological Disease Mechanisms and Treatments
- S100 Proteins and Annexins
- Sports injuries and prevention
- Radioactivity and Radon Measurements
- Cerebrovascular and Carotid Artery Diseases
Boğaziçi University
2017-2024
University of Stuttgart
2022-2024
Abstract Stroke is one of the leading causes adult disability affecting millions people worldwide. Post‐stroke cognitive and motor impairments diminish quality life functional independence. There an increased risk having a second stroke developing secondary conditions with long‐term social economic impacts. With increasing number incidents, shortage medical professionals limited budgets, health services are struggling to provide care that can break vicious cycle stroke. Effective post‐stroke...
Botulinum toxin type A (BTX-A) is widely used for spasticity management and mechanically aims at reducing passive resistance the joint widening range of movement. However, recent experiments on acute BTX-A effects showed that injected rat tibialis anterior (TA) muscle's forces increased length active force exertion (lrange) did not change. Additionally, was shown to spread into non-injected muscles in compartment affect their mechanics. Whether those persist long-term highly important, but...
This study reviews the relationship between muscle-tendon biomechanics and joint function, with a particular focus on how cerebral palsy (CP) affects this relationship. In healthy individuals, muscle size is critical determinant of strength, volume, cross-sectional area, moment arm correlating knee ankle torque for different isometric/isokinetic contractions. However, in CP, impaired growth contributes to pathophysiology even though only limited number studies have investigated impact...
Local application of botulinum toxin type-A (BTX-A) is commonly used for spasticity management in patients with cerebral palsy (CP), stroke, multiple sclerosis, as well dystonia. However, recent studies on muscle mechanics have shown results contradictory to treatment aims (increased passive resistance, narrower joint range motion). This ascribed structure adaptations characterized by collagen increase, hereby this should be controlled. the mechanisms these are not understood. Within study,...
In cerebral palsy, an increased pathological resistance against knee extension is observed on rest and during walking. The source of these high forces that cause the joint to be held in a forced flexion position attributed passive active mechanics spastic flexor muscles. However, studies directly quantifying such intraoperative experiments are sparse. this study, force production capacities semitendinosus gracilis muscles were measured by mechanical tests, under conditions. order establish...