- Osteoarthritis Treatment and Mechanisms
- Cancer-related molecular mechanisms research
- Pain Mechanisms and Treatments
- Peroxisome Proliferator-Activated Receptors
- Nerve injury and regeneration
- Peptidase Inhibition and Analysis
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Stress Responses and Cortisol
- Periodontal Regeneration and Treatments
- Temporomandibular Joint Disorders
- Musculoskeletal synovial abnormalities and treatments
- Metal Alloys Wear and Properties
- Bone Tumor Diagnosis and Treatments
- Circular RNAs in diseases
- Histone Deacetylase Inhibitors Research
- Chemokine receptors and signaling
Hospital of Stomatology, Sun Yat-sen University
2017-2024
Stomatology Hospital
2017-2024
Sun Yat-sen University
2017-2024
Abstract Histone deacetylases (HDACs) are important in chronic inflammation, and inflammatory responses affect synovium‐derived mesenchymal stem cell (SMSC) function temporomandibular joint repair. However, the effect of HDACs on SMSC activation remains unclear. In this study, fibroblast‐like synoviocytes obtained from osteoarthritis patients met minimal criteria. Interleukin 1β (IL‐1β) upregulated IL‐6 IL‐8 expression SMSCs through nuclear factor‐κB (NF‐κB) pathway activation. upregulation...
Objective To study the clinical and radiologic findings of synovial chondromatosis (SC) provide a reference for its diagnosis by using cone-beam computed tomography (CBCT) arthrography. Methods Twenty-one patients presenting to our clinic with SC diagnosed histopathologically were included in study. The manifestations, radiographic findings, surgical treatment, histopathologic features disease investigated. temporomandibular joint (TMJ) on CBCT arthrography...