- Adipokines, Inflammation, and Metabolic Diseases
- Adipose Tissue and Metabolism
- Diabetes and associated disorders
- Exercise and Physiological Responses
- Immune Cell Function and Interaction
- Fatty Acid Research and Health
- Cardiovascular Disease and Adiposity
- Herbal Medicine Research Studies
- Cancer, Stress, Anesthesia, and Immune Response
- Cardiac Arrhythmias and Treatments
- Diet, Metabolism, and Disease
- Pharmacological Effects of Natural Compounds
- IL-33, ST2, and ILC Pathways
- Sepsis Diagnosis and Treatment
- Cardiovascular Conditions and Treatments
- Regulation of Appetite and Obesity
- Dietary Effects on Health
- Cerebrospinal fluid and hydrocephalus
- Muscle metabolism and nutrition
- Occupational Health and Performance
- Immune cells in cancer
- Cardiovascular and exercise physiology
- Nutrition and Health in Aging
- Health and Lifestyle Studies
- Fetal and Pediatric Neurological Disorders
Universidade Cruzeiro do Sul
2018-2024
Curtin University
2022-2023
Centro Universitário Católico do Sudoeste do Paraná
2018
Universidade Federal de São Paulo
2011
We investigated the effects of oral L-glutamine (Gln) supplementation, associated or not with physical exercises, in control glycemia, oxidative stress, and strength/power knee muscles elderly women. Physically active (n = 21) sedentary 23) women aged 60 to 80 years were enrolled study. Plasma levels D-fructosamine, insulin, reduced (GSH) oxidized (GSSG) glutathione, iron, uric acid, thiobarbituric acid-reactive substances (TBARs) (lipoperoxidation product), as well extensor/flexor muscle...
Goto-Kakizaki (GK) rats develop a well-defined insulin resistance (IR) and type 2 diabetes mellitus (T2DM) without presenting obesity. The lymphocyte profile in nonobese diabetic conditions is not yet characterized. Therefore, GK were chosen to explore T (TL) dynamics at various stages (21, 60, 120 days) compared Wistar rats. exhibit progressive disruption of glucose regulation, with early intolerance 21 days reduced sensitivity 60 days, confirming IR. Glucose transporter 1 (GLUT1)...
Obesity can lead to a chronic systemic inflammatory state that increases the risk of cancer development. Therefore, this study aimed evaluate alterations in tumor non-infiltrated lymphocytes function and melanoma growth animals maintained on high-fat diet and/or moderate physical exercise program murine model melanoma.Female mice were randomly divided into eight groups: 1) normolipidic control (N), 2) + (NM), 3) (H), 4) (HM), 5) (NE), 6) (NEM), 7) (HE), 8) (HEM). After 8 weeks treatment...
What is the central question of this study? Is lymphocyte DNA methylation differentially modulated by resistance training and aerobic exercise in older women? main finding its importance? The practice led to an increased global lymphocytes. exercise-induced increase inflammatory genes may be associated with immune function impairment during ageing.Ageing-induced gene expression through a reduction might contribute chronic diseases. Regular physical practices, turn, are decrease incidence We...
Brown adipose tissue (BAT) is a potential target to treat obesity and diabetes, dissipating energy as heat. Type 2 diabetes (T2D) has been associated with obesogenic diets; however, T2D was also reported in lean individuals be genetic factors. We aimed investigate the differences between obese models of insulin resistance (IR) elucidate mechanism BAT metabolism dysfunction different IR animal models: model (lean GK rats) (diet-induced Wistar at 8 weeks age fed high-carbohydrate (HC),...
Background/Objectives: Goto-Kakizaki (GK) rats exhibit insulin resistance and type 2 diabetes mellitus (T2DM) without obesity. This study explored the effects of ω-3 fatty acid supplementation on T lymphocyte polarization in Wistar (WT) GK rats. Methods: They were administered acid-rich fish oil (FO) containing eicosapentaenoic (540 mg/g) docosahexaenoic acids (100 by oral gavage at g/kg, thrice a week for 8 weeks. The control groups (WT CT CT) received same volume water. following...
Abstract This study aimed to investigate the impact of a 16-week dance-based aerobic exercise program on lymphocyte function in healthy and type 2 diabetes mellitus (T2DM) women. We enrolled 23 women: 11 with T2DM 12 non-diabetic controls. Initially, we performed anthropometry body composition measurements, afterwards, plasma levels C-reactive protein, lipids, glucose were determined. used flow cytometry measure CD25 CD28 expression circulating lymphocytes, T-regulatory (Treg) cell...
(a mushroom used in traditional Chinese medicine) compounds may attenuate ageing-related physiological changes and restore normal immunity. However, studies on the effects of
We determined the prevalence of metabolic syndrome (MetS) among military police officers (MPOs) from radio patrol program Military Police Sao Paulo State (PMESP). Towards this goal, we analyzed following characteristics: shift duty (daytime or nighttime patrol), service length in PMESP, education level attained, weekly alcohol consumption, smoking, and physical activity 93 MPOs. The MPO groups were created based on work [daytime (n=48) (n=45)], years experience [≤3 ≥10 (n=45)]. overall MetS...
Obesity is related to the establishment of chronic inflammation and metabolic diseases, but it can be positively influenced by regular practice physical activity. The study aimed compare anthropometric, metabolic, inflammatory parameters physically active Military Police Officers (MPOs) with those who are less active. Sixty male MPOs, low activity (n=28) (n=32) participated. following were measured: plasma cytokine levels, C-reactive protein (CRP) circulating glucose triglyceride (TAG)...
Prenatal diagnosis of isolated coronary artery fistulae is extremely rare. Most the previously reported cases prenatal have been associated with additional complex congenital cardiac anomalies. We report a case very large fistula connecting left to right ventricle, diagnosed at 28 weeks' gestation, as sole lesion. Bidimensional fetal echocardiography image four chamber view and outflow tracts were normal well ductal aortic arch ventricular size contractility. A ventriculocoronary was...
The ductus arteriosus (DA) emerged from the pulmonary trunk and connects with descending aorta. normal Doppler evaluation depends on gestational age pulsatility index (PI) must be greater than 1.9. Anatomical functional problems can occur as aneurysm of DA restrictive flow. anatomical changes caused by in blood flow / or morphology especially last trimester. Description cases: 10 cases fetuses (GA) ranging 28 to 37 weeks: 2 aneurysms (diameters 5 8 mm) morphological alteration elongated,...
It is well-known the alterations that occur in immune response with aging can generate an imbalance of leading to a low-grade chronic inflammation. Some studies have described decrease proliferative capacity Th1 cells elderly. The between and Th2 seems play role development autoimmune inflammatory diseases. PURPOSE: Therefore, aim this study was evaluate responses verify Th1/ ratio elderly women engaged different exercise programs. METHODS: Initially, 27 (65± 3.2 years old) were selected...