A5061376932- Essential Oils and Antimicrobial Activity
- Plant chemical constituents analysis
- Peptidase Inhibition and Analysis
- Layered Double Hydroxides Synthesis and Applications
- Cannabis and Cannabinoid Research
- Natural product bioactivities and synthesis
- Neuropeptides and Animal Physiology
- Synthesis and biological activity
- Dye analysis and toxicity
- Phytochemicals and Antioxidant Activities
- Biochemical and Structural Characterization
- Plant biochemistry and biosynthesis
- Bioactive natural compounds
- Mesoporous Materials and Catalysis
- Biochemical Analysis and Sensing Techniques
- Inflammatory mediators and NSAID effects
- Phytochemistry and Bioactive Compounds
- Pomegranate: compositions and health benefits
- Saffron Plant Research Studies
- Mercury impact and mitigation studies
- Redox biology and oxidative stress
- GABA and Rice Research
- Alcohol Consumption and Health Effects
- Edible Oils Quality and Analysis
- Nanomaterials for catalytic reactions
University of Chieti-Pescara
2022-2025
Leonardo (Italy)
2022
Several processes have been developed in the past to selectively extract oleuropein and its aglycones from olive derived materials. In present manuscript, we outline a novel approach for processing leaves aqueous extracts. This allowed first select microwave irradiation as methodology able provide large enrichment oleuropein. Subsequently, use of lamellar solids led selective high yield concentration same. Adsorption on also largely contributed long term chemical stability Finally, an...
In the present study we investigated capacities of a panel 25 solid sorbents represented by layered structures, inorganic oxides and hydroxides, phyllosilicates, to effectively remove in high yield Tartrazine (E102) Brilliant Blue FCF (E133) from aqueous solutions, more notable, green colored food matrices. Quantification title compounds have been achieved HPLC-DAD analyses. Contents E102 E133 real samples were range 1.3-36.5 μg/mL 1.0-20.1 μg/mL, respectively. After treatment 1 min., most...
Nowadays, several processes to enrich desired bioactive compounds in plant extracts have been developed. The objective of the present study was assess performance bovine serum albumin increasing extractive yields anthraquinones and diarylheptanoids from their respective raw powder extracts. Aloe emodin, rhein, chrysophanol, Polygonum cuspidatum, Senna alexandrina, Rhamnus frangula, Rheum palmatum, curcumin Curcuma longa were analyzed parent dry extracts, solubilized either with water,...
Prolidase (EC.3.4.13.9) is a dipeptidase known nowadays to play pivotal role in several physiological and pathological processes. More particular, this enzyme involved the cleavage of proline- hydroxyproline-containing dipeptides (imidodipeptides), thus finely regulating homeostasis free proline hydroxyproline. Abnormally high or low levels prolidase have been found numerous acute chronic syndromes affecting humans (chronic liver fibrosis, viral hepatitis, cancer, neurological disorders,...
A series of five naturally occurring oxyprenylated phenylpropanoids, namely, the coumarins auraptene (7-geranyloxycoumarin) 1 and 7-isopentenyloxycoumarin 2, coumaric acid ferulic derivatives, 4’-isopentenyloxycoumaric 3, boropinic 4, 4’-geranyloxyferulic 5 were tested for their effects on mitochondrial functionality using organophosphate pesticides glyphosate chlorpyrifos, resveratrol, as reference. While not showing an appreciable in vitro antioxidant activity, virtually no or a little...
In a search for methods of manufacturing bitter principles from Gentiana lutea, mainly represented by gentiopicroside (1) and amarogentin (2), as an alternative to extraction the roots this plant, in short communication it is shown that leaves plant can be regarded additional source such phytochemicals. Extraction G. lutea was coupled solid-phase adsorption differently structured solids separation technology step, providing selective isolation both these secondary metabolites good excellent...
Abstract Previous and recent literature acquisitions suggested that cultured calli are an efficient meaningful model to investigate the extent fate of prenylation phenylpropanoid cores in plants belonging Rutaceae Apiaceae families upon administration putative biosynthetic precursors. To this concern, present manuscript, we investigated effect supplementation ferulic acid umbelliferone on biosynthesis their oxyprenylated counterparts Ferulago campestris (Besser) Grecescu (Fam. Apiaceae)...
In this manuscript the biomolecular mechanism of action natural colon cancer chemopreventive agent 4'-geranyloxyferulic acid in cultured Caco-2 cells has been investigated. It was first demonstrated how application phytochemical led to a time- and dose-dependent decrease cell viability parallel massive generation reactive oxygen species induction caspases 3 9, finally providing apoptosis. This event is accompanied by deep modifications key pro-apoptotic targets like CD95, DR4 5, cytochrome...
Abstract Oxyprenylated secondary metabolites of plant, fungal, and microbial origin have emerged as biologically active natural compounds with a great potential for the next future. While originally obtained from respective sources merely by conventional techniques phytochemical practice like maceration, percolation, Soxhlet extractions, during last five years novel alternative experimental protocols to get such chemicals in higher yields purity degree and/or form enriched phytopreparations...