A5023731726- Cancer Genomics and Diagnostics
- Lung Cancer Treatments and Mutations
- Plant chemical constituents analysis
- Layered Double Hydroxides Synthesis and Applications
- Pancreatic and Hepatic Oncology Research
- Genetic factors in colorectal cancer
- Synthesis of Organic Compounds
- Synthesis and biological activity
- RNA modifications and cancer
- Essential Oils and Antimicrobial Activity
- Mesoporous Materials and Catalysis
- Medicinal Plants and Neuroprotection
- Natural product bioactivities and synthesis
- Diet, Metabolism, and Disease
- Medical Imaging and Pathology Studies
- Dye analysis and toxicity
- Cannabis and Cannabinoid Research
- Bioactive natural compounds
- Phytochemistry and Biological Activities
- Neurological Disease Mechanisms and Treatments
- Medicinal plant effects and applications
- Phytochemical Studies and Bioactivities
- Saffron Plant Research Studies
- Phytochemistry and Bioactive Compounds
- Analytical Chemistry and Chromatography
University of Naples Federico II
2022-2024
Federico II University Hospital
2022-2024
University of Chieti-Pescara
2020-2023
Leonardo (Italy)
2022
Heart Foundation
1995
In the present study we investigated capacities of a panel 25 solid sorbents represented by layered structures, inorganic oxides and hydroxides, phyllosilicates, to effectively remove in high yield Tartrazine (E102) Brilliant Blue FCF (E133) from aqueous solutions, more notable, green colored food matrices. Quantification title compounds have been achieved HPLC-DAD analyses. Contents E102 E133 real samples were range 1.3-36.5 μg/mL 1.0-20.1 μg/mL, respectively. After treatment 1 min., most...
Abstract Background Auraptene (AUR) and naringenin (NAR) are citrus-derived phytochemicals that influence several biological mechanisms associated with cognitive decline, including neuronal damage, oxidative stress inflammation. Clinical evidence of the efficacy a nutraceutical potential to enhance function in cohorts at risk decline would be great value from preventive perspective. The primary aim this study is determine effects 36-week treatment citrus peel extract standardized levels AUR...
Biomarker testing is mandatory for the clinical management of patients with advanced non-small cell lung cancer (NSCLC). Myriads technical platforms are now available biomarker analysis differences in terms multiplexing capability, analytical sensitivity, and turnaround time (TAT). We evaluated performance diagnostic workflows 24 representative Italian institutions performing molecular tests on a series artificial reference specimens built to mimic routine samples. Sample sets eight slides...
A series of five naturally occurring oxyprenylated phenylpropanoids, namely, the coumarins auraptene (7-geranyloxycoumarin) 1 and 7-isopentenyloxycoumarin 2, coumaric acid ferulic derivatives, 4’-isopentenyloxycoumaric 3, boropinic 4, 4’-geranyloxyferulic 5 were tested for their effects on mitochondrial functionality using organophosphate pesticides glyphosate chlorpyrifos, resveratrol, as reference. While not showing an appreciable in vitro antioxidant activity, virtually no or a little...
In a search for methods of manufacturing bitter principles from Gentiana lutea, mainly represented by gentiopicroside (1) and amarogentin (2), as an alternative to extraction the roots this plant, in short communication it is shown that leaves plant can be regarded additional source such phytochemicals. Extraction G. lutea was coupled solid-phase adsorption differently structured solids separation technology step, providing selective isolation both these secondary metabolites good excellent...
Abstract Previous and recent literature acquisitions suggested that cultured calli are an efficient meaningful model to investigate the extent fate of prenylation phenylpropanoid cores in plants belonging Rutaceae Apiaceae families upon administration putative biosynthetic precursors. To this concern, present manuscript, we investigated effect supplementation ferulic acid umbelliferone on biosynthesis their oxyprenylated counterparts Ferulago campestris (Besser) Grecescu (Fam. Apiaceae)...
Cell-free DNA (cfDNA) has long been established as a useful diagnostic and prognostic tool in variety of clinical settings, ranging from infectious to cardiovascular neoplastic diseases. However, non-neoplastic diseases can act confounders impacting on the amount cfDNA shed bloodstream technical feasibility tumour derived free circulating nucleic acids selecting patients with cancer. Here, we investigated potential impact other pathological processes stratification 637 FIT+ patients. A...
Background: Colorectal Cancer screening programs are effective in reducing incidence and mor-tality. In Europe, every FIT+ patient is referred to colonoscopy. Available data shows that ~75.0% of these patients negative. It desirable select at greater risk having a positive Methods: 711 subjects, aged 50-74, attending the program ASL-NA-3-SUD (Na-ples, Italy), were enrolled cross-sectional study evaluate performance QuantiDNA™ test non-inferiority an alternative approach (AAP). This...
Personalized medicine has revolutionized the clinical management of patients with solid tumors. However, large volumes molecular data derived from next-generation sequencing (NGS) and lack harmonized bioinformatics pipelines drastically impact A possible solution to streamline interpretation reporting NGS would be adopt automated analysis software. In this study, we tested efficiency Navify Mutation Profiler (nMP) software in improving diagnostic routine samples This study included one...