- Plant Water Relations and Carbon Dynamics
- Atmospheric and Environmental Gas Dynamics
- Climate variability and models
- Fluid Dynamics and Turbulent Flows
- Wind and Air Flow Studies
- Flow Measurement and Analysis
- Cardiac Arrest and Resuscitation
- Meteorological Phenomena and Simulations
- Genomics and Phylogenetic Studies
- RNA and protein synthesis mechanisms
- Cardiac Ischemia and Reperfusion
- Mechanical Circulatory Support Devices
- Metabolism and Genetic Disorders
- Heart Failure Treatment and Management
- RNA modifications and cancer
- Cardiac electrophysiology and arrhythmias
- Reservoir Engineering and Simulation Methods
- Hydrology and Drought Analysis
- Chromosomal and Genetic Variations
- Climate Change Policy and Economics
- Cardiac Valve Diseases and Treatments
- Hydrology and Watershed Management Studies
- Anesthesia and Neurotoxicity Research
- Cynara cardunculus studies
- Energy Load and Power Forecasting
Sapienza University of Rome
2006-2024
Federico II University Hospital
2024
University of St. Gallen
2022
Azienda Sanitaria Ospedaliera S.Croce e Carle Cuneo
2012-2022
Ospedale Civile di Vittorio Veneto
2022
CMCC Foundation - Euro-Mediterranean Center on Climate Change
2020-2021
Università degli Studi della Tuscia
2014-2021
Institute for Agricultural and Forest Systems in the Mediterranean
2020
Fondazione Salvatore Maugeri
1984-2020
Istituto per il Sistema Produzione Animale in Ambiente Mediterraneo
2020
Abstract The eddy covariance is a powerful technique to estimate the surface-atmosphere exchange of different scalars at ecosystem scale. EC method central component Integrated Carbon Observation System, monitoring network for greenhouse gases across European Continent. data processing sequence applied collected raw complex, and multiple robust options steps are often available. For System similar networks, standardisation methods essential avoid methodological biases improve comparability...
Abstract. Mapping in-situ eddy covariance measurements of terrestrial land-atmosphere fluxes to the globe is a key method for diagnosing Earth system from data-driven perspective. We describe first global products (called X-BASE) newly implemented up-scaling framework, FLUXCOM-X. The X-BASE comprise estimates CO2 net ecosystem exchange (NEE), gross primary productivity (GPP) as well evapotranspiration (ET) and, time, novel fully transpiration product (ETT), at high spatial (0.05°) and...
To evaluate the accuracy, consumable cost and time around testing (TAT) of a next-generation sequencing (NGS) assay, Ion Torrent AmpliSeq Colon Lung Cancer Panel, as an alternative to Sanger genotype KRAS, NRAS BRAF in colorectal cancer patients.The panel was first verified on cell lines control samples then prospectively applied routine specimens (n=114), with reference.The detected mutant alleles at 5% level correctly classified all tissues. The assay successfully carried out most (95.6%)...
Abstract. Mapping in situ eddy covariance measurements of terrestrial land–atmosphere fluxes to the globe is a key method for diagnosing Earth system from data-driven perspective. We describe first global products (called X-BASE) newly implemented upscaling framework, FLUXCOM-X, representing an advancement previous generation FLUXCOM terms flexibility and technical capabilities. The X-BASE are comprised estimates CO2 net ecosystem exchange (NEE), gross primary productivity (GPP),...
ABSTRACT We investigated the basis of carbapenem resistance 17 multidrug-resistant Acinetobacter baumannii clinical isolates collected from 2004 to 2005 at Saint George University Hospital in Beirut, Lebanon. A. were clonally related and susceptible colistin trimethoprim-sulfamethoxazole, or intermediate ampicillin-sulbactam meropenem, resistant all other antimicrobials. Conjugation experiments demonstrated that imipenem could be transferred along with a plasmid containing...
The aim of the study was to test 1) whether chronic and stable coronary artery disease (CAD) could downregulate epicardial fat adrenomedullin synthesis secretion, decrease intracoronary plasma levels, 2) levels be related adipose tissue gene protein expression in subjects with CAD. We examined 12 patients CAD who required bypass graft (CABG) 10 non-CAD underwent cardiac surgery for valve replacement. Plasma were measured peripheral vein circulation, left (LCA) sinus (CS) during angiography....
Abstract. The sources of systematic error responsible for introducing significant biases in the eddy covariance (EC) flux computation are manifold, and their correct identification is made difficult by lack reference values, complex stochastic dynamics, high level noise characterizing raw data. This work contributes to overcoming such challenges an innovative strategy EC data cleaning. proposed includes a set tests aimed at detecting presence specific error, as well outlier detection...
Abstract Background De novo RNA-Seq assembly is a powerful method for analysing transcriptomes when the reference genome not available or poorly annotated. However, due to short length of Illumina reads it usually impossible reconstruct complete sequences complex genes and alternative isoforms. Recently emerged possibility generate long RNA reads, such as PacBio Oxford Nanopores, may dramatically improve quality, thus consecutive analysis. While reference-based tools were recently developed,...
Abstract We report a novel case of multiple endocrine neoplasia type 2A (MEN 2A) associated with two mutations the protooncogene RET. One affects codon 634 and causes cysteine to arginine substitution; second at 640 an alanine glycine substitution in transmembrane region. The were present on same RET allele detected germline tumor DNA. Both de novo, i.e. they not found DNA parents or relatives. Immunohistochemical RT-PCR analysis showed that pheochromocytoma expressed calcitonin as well both...
The aim of this study was to assess safety and effectiveness recombinant activated factor VII (rFVIIa) in patients with refractory bleeding undergoing acute aortic dissection surgery deep hypothermic circulatory arrest.Propensity score-matched analysis.University hospital.Twenty-three cardiac receiving rFVIIa compared 23 matched controls.An intravenous bolus (70 microg/kg) administered at the end a complete transfusion protocol. Five received operating room, 18 intensive care unit. Four unit...
Maternally Inherited Diabetes and Deafness (MIDD) is a rare form of diabetes due to defects in mitochondrial DNA (mtDNA). 3243 A>G the mutation most frequently associated with this condition, but other mtDNA variants have been linked diabetic phenotype suggestive MIDD. From 1989 2009, we clinically diagnosed 11 children. Diagnosis was based on presence one or more following criteria: 1) maculopathy; 2) hearing impairment; 3) maternal heritability diabetes/impaired fasting glucose and/or...
Abstract The agreement of Leaf Area Index (LAI) assessments from three indirect methods, i.e. the LAI–2200 Plant Canopy Analyzer, SS1 SunScan Analysis System and Digital Hemispherical Photography (DHP) was evaluated for four canopy types, a short rotation coppice plantation (SRC) with poplar, Scots pine stand, Pedunculate oak stand maize field. In SRC in field, measurements were compared direct (litter fall harvesting). low LAI range (0 to 2) discrepancies partly explained by inability...
Abstract Background The investigation of transcriptome profiles using short reads in non-model organisms, which lack well-annotated genomes, is limited by partial gene reconstruction and isoform detection. In contrast, long-reads sequencing techniques revealed their potential to generate complete transcript assemblies even when a reference genome lacking. Cynara cardunculus var. altilis (DC) (cultivated cardoon) perennial hardy crop adapted dry environments with many industrial nutraceutical...