Clarissa Ferrari
A5027464378- Dementia and Cognitive Impairment Research
- Functional Brain Connectivity Studies
- Transcranial Magnetic Stimulation Studies
- Alzheimer's disease research and treatments
- Schizophrenia research and treatment
- Personality Disorders and Psychopathology
- Psychopathy, Forensic Psychiatry, Sexual Offending
- Child and Adolescent Psychosocial and Emotional Development
- Tryptophan and brain disorders
- Mental Health Treatment and Access
- EEG and Brain-Computer Interfaces
- Bipolar Disorder and Treatment
- Stress Responses and Cortisol
- Neural and Behavioral Psychology Studies
- Colorectal Cancer Screening and Detection
- Pancreatic and Hepatic Oncology Research
- Advanced Neuroimaging Techniques and Applications
- Soil Geostatistics and Mapping
- Healthcare Decision-Making and Restraints
- Suicide and Self-Harm Studies
- Gastrointestinal Bleeding Diagnosis and Treatment
- Neurological Disease Mechanisms and Treatments
- COVID-19 and Mental Health
- Stroke Rehabilitation and Recovery
- Pancreatitis Pathology and Treatment
Fondazione Poliambulanza Istituto Ospedaliero
2022-2025
Centro San Giovanni di Dio Fatebenefratelli
2014-2023
Istituti di Ricovero e Cura a Carattere Scientifico
2014-2023
ORCID
2021
University of Brescia
2021
Università degli Studi eCampus
2016
King's College London
2016
Dalhousie University
2016
Ferrari (Italy)
2016
University of Milan
2016
Abstract Repetitive transcranial magnetic stimulation (rTMS) is emerging as a non-invasive therapeutic strategy in the battle against Alzheimer’s disease. disease patients primarily show alterations of default mode network for which precuneus key node. Here, we hypothesized that targeting with TMS represents promising to slow down cognitive and functional decline patients. We performed randomized, double-blind, sham-controlled, phase 2, 24-week trial determine safety efficacy...
Objective: To develop and update evidence- consensus-based guidelines on laparoscopic robotic pancreatic surgery. Summary Background Data: Minimally invasive surgery (MIPS), including surgery, is complex technically demanding. Minimizing the risk for patients requires stringent, evidence-based guidelines. Since International Miami Guidelines MIPS in 2019, new developments key publications have been reported, necessitating an update. Methods: Evidence-based 22 topics 8 domains were proposed:...
Abstract Background An international Delphi panel has defined a harmonized protocol (HarP) for the manual segmentation of hippocampus on MR. The aim this study is to concurrent validity HarP toward local protocols, and its major sources variance. Methods Fourteen tracers segmented 10 Alzheimer's Disease Neuroimaging Initiative (ADNI) cases scanned at 1.5 T 3T following qualified based through standard web‐platform resegmented HarP. five most accurate followed segment 15 ADNI acquired three...
Given the limited effectiveness of pharmacological treatments, non-pharmacological interventions to treat Alzheimer's disease (AD) have gained attention in recent years. The aim present study is investigate effects anodal tDCS (AtDCS) combined with memory training on face-name associations an AD patient sample.Thirty six patients were randomly assigned one three groups: Group 1, AtDCS plus individualized computerized training; 2, placebo 3, motor training.A general improvement performance...
Parkinson's disease (PD) is characterized by both motor and cognitive deficits. In PD, physical exercise has been found to improve functioning. Recent studies demonstrated that repeated sessions of transcranial direct current stimulation led an increased performance in tasks patients with PD.The present study investigated the effects anodal applied over dorsolateral prefrontal cortex combined therapy PD patients.A total 20 were assigned 1 2 groups: group 1, plus (n = 10) or 2, placebo 10)....
<h3>Objectives:</h3> The aim of this study was to investigate predictors progressive cognitive deterioration in patients with suspected non–Alzheimer disease pathology (SNAP) and mild impairment (MCI). <h3>Methods:</h3> We measured markers amyloid (CSF β-amyloid 42) neurodegeneration (hippocampal volume on MRI cortical metabolism [<sup>18</sup>F]-fluorodeoxyglucose–PET) 201 MCI clinically followed for up 6 years detect deterioration. categorized as A+/A− N+/N− based presence/absence...
Memory is the capacity to store, maintain, and retrieve events or information from mind. Difficulties in verbal episodic memory commonly occur healthy aging. In this paper, we assess hypothesis that anodal transcranial direct current stimulation (tDCS) applied over dorsolateral prefrontal cortex (DLPFC) parietal (PARC) could facilitate a group of 32 older adults young subjects relative sham using single-blind randomized controlled design. Each participant underwent two sessions tDCS (left...
Increased levels of inflammation have been associated with a poorer response to antidepressants in several clinical samples, but these findings had limited by low reproducibility biomarker assays across laboratories, difficulty predicting probability on an individual basis, and unclear molecular mechanisms. Here we measured absolute mRNA values (a reliable quantitation number molecules) Macrophage Migration Inhibitory Factor interleukin-1β previously published sample from randomized...
<h3>Importance</h3> Cerebral amyloidosis is a key abnormality in Alzheimer disease (AD) and can be detected vivo with positron emission tomography (PET) ligands. Although amyloid PET has clearly demonstrated analytical validity, its clinical utility debated. <h3>Objective</h3> To evaluate the incremental diagnostic value of florbetapir F 18 addition to routine assessment patients evaluated for cognitive impairment. <h3>Design, Setting, Participants</h3> The Incremental Diagnostic Value...
Abstract The mRNA expression signatures associated with the ‘pro-inflammatory’ phenotype of depression, and differential depression subtypes effects antidepressants, are still unknown. We examined 130 depressed patients (58 treatment-resistant, 36 antidepressant-responsive currently untreated) 40 healthy controls from BIODEP study, used whole-blood qPCR to measure 16 candidate mRNAs, some never measured before: interleukin ( IL)-1-beta , IL-6 TNF-alpha macrophage inhibiting factor MIF ),...
Abstract Compelling evidence demonstrates that some individuals suffering from major depressive disorder (MDD) exhibit increased levels of inflammation. Most studies focus on inflammation-related proteins, such as serum or plasma C-reactive protein (CRP). However, the immune-related modifications associated with MDD may be not entirely captured by CRP alone. Analysing mRNA gene expression levels, we aimed to identify broader molecular phenotypes MDD. We examined 168 non-interventional,...
Capsule endoscopy reading is time consuming, and readers are required to maintain attention so as not miss significant findings. Deep convolutional neural networks can recognise relevant findings, possibly exceeding human performances reducing the of capsule endoscopy. Our primary aim was assess non-inferiority artificial intelligence (AI)-assisted versus standard for potentially small bowel bleeding lesions (high P2, moderate P1; Saurin classification) at per-patient analysis. The mean in...
Transcranial magnetic stimulation (TMS)-evoked potentials (TEPs) allow one to assess cortical excitability and effective connectivity in clinical basic research. However, obtaining clean TEPs is challenging due the various TMS-related artifacts that contaminate electroencephalographic (EEG) signal when TMS pulse delivered. Different preprocessing approaches have been employed remove artifacts, but degree of artifact reduction or distortion introduced this phase analysis still unknown....
In recent years, the potential usefulness of cognitive training procedures in normal aging and mild impairment (MCI) have received increased attention.The main aim this study was to evaluate efficacy face-to-face virtual reality rehabilitation system (VRRS) compare it that treatment as usual for individuals with MCI. Moreover, we assessed possibility prolonging effects a telerehabilitation system.A total 49 subjects MCI were assigned 1 3 groups randomized controlled trial design: (a) those...
Adolescents have been deeply exposed to negative consequences of social distancing imposed by Covid-19. There is a lack longitudinal studies regarding the impact on adolescents this unfavorable condition, and their results are controversial. The aim present prospective study assess psychopathological symptoms in adolescent students over time evaluate what type Covid-19 pandemic had adolescents. Moreover, association between mental health indexes, potential risk resilience factors...