A5057256135- Dementia and Cognitive Impairment Research
- Neurological Disease Mechanisms and Treatments
- Machine Learning in Healthcare
- Medicinal Plants and Neuroprotection
- Alzheimer's disease research and treatments
Istituti di Ricovero e Cura a Carattere Scientifico
2019-2022
Centro San Giovanni di Dio Fatebenefratelli
2019-2022
University of Geneva
2019
Research investigating treatments and interventions for cognitive decline fail due to difficulties in accurately recognizing behavioral signatures the presymptomatic stages of disease. For this validation study, we took our previously constructed digital biomarker-based prognostic models focused on generalizability robustness models.We validated characterizing subjects using biomarkers a longitudinal, multi-site, 40-month prospective study collecting data memory clinics, general practitioner...
Abstract Background Auraptene (AUR) and naringenin (NAR) are citrus-derived phytochemicals that influence several biological mechanisms associated with cognitive decline, including neuronal damage, oxidative stress inflammation. Clinical evidence of the efficacy a nutraceutical potential to enhance function in cohorts at risk decline would be great value from preventive perspective. The primary aim this study is determine effects 36-week treatment citrus peel extract standardized levels AUR...
Research investigating treatments and interventions for cognitive decline Alzheimer's disease (AD) suffer due to difficulties in accurately identifying individuals at risk of AD the pre-symptomatic stages disease. There is an urgent need better identification such order enable earlier treatment properly stage stratify participants clinical trials intervention studies. Although some biological measures (biomarkers) can identify Alzheimer's-related changes before significant function occur,...