- Neonatal Health and Biochemistry
- Hair Growth and Disorders
- Acute Kidney Injury Research
- Metabolism and Genetic Disorders
- melanin and skin pigmentation
- Skin Protection and Aging
- Adipose Tissue and Metabolism
- Sepsis Diagnosis and Treatment
- Acne and Rosacea Treatments and Effects
- Renal function and acid-base balance
- Diabetes and associated disorders
- Gout, Hyperuricemia, Uric Acid
- Radiomics and Machine Learning in Medical Imaging
- Thyroid Disorders and Treatments
- Pancreatic function and diabetes
- Advanced Glycation End Products research
- Nerve injury and regeneration
- S100 Proteins and Annexins
- Dermatoglyphics and Human Traits
- Hereditary Neurological Disorders
- Eicosanoids and Hypertension Pharmacology
- Muscle and Compartmental Disorders
- Enhanced Recovery After Surgery
- Urinary Tract Infections Management
- Folate and B Vitamins Research
Eskişehir Osmangazi University
2018-2024
Eskişehir Osmangazi Üniversitesi Tıp Fakültesi Hastanesi
2023-2024
Sivas State Hospital
2020-2022
Kırklareli University
2020
Okmeydanı Eğitim ve Araştırma Hastanesi
2020
Koç University
2020
Eskişehir City Hospital
2016-2018
State Hospital
2018
Abstract Background Androgenetic alopecia ( AGA ) is the most common cause of in men. In literature, although there are vitro studies investigating relationship between oxidative stress and , any vivo study does not exist. Aim Our aim was to evaluate status male patients with early‐onset by measuring total oxidant levels TOS ), antioxidant TAS index OSI ). Methods included 33 30 healthy men ages 18 years old. measurements were taken, calculated. Results When compared patient control groups,...
Rosacea is a chronic, inflammatory dermatosis which develops due to the effect of genetic and environmental factors.To evaluate oxidative stress in rosacea patients by measuring serum total antioxidant status (TAS), oxidant (TOS), index (OSI) advanced oxidation protein products (AOPP) levels our study.Our study included healthy volunteers aged between 18 65 years. Total status, TOS AOPP were measured OSI was calculated.The 70 30 as control group. When TAS, TOS, compared groups, there no...
Abstract Subacute thyroiditis (SAT) is an inflammatory disorder of the thyroid gland. Although its etiology not fully understood, it believed to occur shortly after viral infections and mostly associated with human leukocyte antigen (HLA)-B*35. Cellular immunity prominent in SAT. Neopterin produced by activated monocytes/macrophages a marker cellular immunity. Its production stimulated interferon gamma (IFN-γ), provided mainly helper T lymphocytes type 1 (Th1) adaptive immune system....
Irisin, a hormone like myokine, is identified to the relation with insulin resistance and metabolic syndrome recently. In literature date, there are no studies evaluating serum irisin levels in psoriasis patients. We aimed elucidate pathogenesis of patients by parameters associated plaque-type vulgaris.The study included 40 moderate-to-severe chronic vulgaris 37 healthy subjects. Body Mass Index (BMI) waist circumference were measured, irisin, fasting blood glucose (FBG), lipid profile,...
Abstract Background Hair graying is a natural process in aging and not usually associated with medical problem. It sometimes may occur at early age called premature hair (PHG). Pathogenesis of PHG clear but it was various systemic diseases such as coronary artery diseases, osteopenia, hypothyroidism. Objectives The purpose this study to evaluate the oxidative stress psychoemotional status individuals PHG. Methods Sixty participants 60 healthy volunteers aged between 18 20 years were included...
Background Oral glucose loading may affect oxidative status during oral tolerance test (OGTT). We aimed to investigate how oxidant and antioxidant markers thiol/disulfide parameters change OGTT.Methods OGTT was performed 42 volunteers who were considered risk of type 2 diabetes divided into three groups (normoglycemic, prediabetes, diabetes) according levels OGTT. Glucose, insulin, c-peptide, total (TAS), (TOS), thiol native investigated with auto-anaylzer for five-hours period.Results...
Abstract Introduction Monocytosis Workflow Optimization rule set has been developed by using mono‐dysplasia‐score to determine reactive monocytosis and prevent unnecessary blood smear of these patients for detection chronic myelomonocytic leukemia cases during complete count. In our study, we aimed examine the contribution set. Methods Adult with monocyte count ≥1.0 10 3 /µL percentage ≥10% were included in study. Blood smears made from samples laboratory. These examined divided into two...
Abstract Background It is important to determine the correlation of CO-RADS classification and computed tomography (CT) patterns lung with laboratory data. To investigate relationship categories CT data in patients a positive RT-PCR test. We also developed structured total scoring system investigated its system. Method The examinations were evaluated terms classification, pattern groups score. Structured score values obtained by including regression analysis. compared according Results A 198...
Abstract Background and Aims Contrast Nephropathy (KN) is acute kidney injury that occurs after exposure to contrast material. Advanced age, chronic disease, heart failure, anemia, hypertension, diabetes mellitus, hyperuricemia have been reported in the literature increase risk of KN development. In addition, oxygen radicals an important place pathogenesis nephropathy Specific biomarkers are used clinics determine oxidative stress antioxidant status. particular, measurement total status...
Objectives: To assess the impact of topical papaverine administration in complete and incomplete colonic anastomosis, by examining bursting pressure, hydroxyproline concentration, collagen content, inflammation levels, inflammatory cell infiltration, neoangiogenesis, necrosis grades. Methods: We performed an experimental study on rats, which they were divided into following 4 groups 16 subjects each. Group 1 [complete anastomosis (CA) without (CA -P) group], 2 [CA with +P) 3 [incomplete...
The measurement of vitamin B12 levels has low sensitivity for the diagnosis deficiency, therefore, clinicians may prefer to decide deficiency with patient's clinic. In this study, diagnostic values classical and advanced clinical complete blood count parameters were investigated find a new marker in deficiency. 150 adult volunteers included study divided into two groups according their (with or without deficiency) hemoglobin anemia). differences correlations laboratory test results between...
Amaç: Bu çalışmanın amacı, kapiller zon elektroforezi (CZE) yöntemi ile bromokrezol yeşili (BCG) yöntemine dayalı albümin ölçümlerinin uyumunu değerlendirmek ve bu yöntemlerin klinik uygulamalarda birbirinin yerine kullanılıp kullanılamayacağını belirlemektir. Çalışma ayrıca, ölçüm sonuçlarının farklı protein paternlerine göre nasıl değişkenlik gösterdiğini incelemiştir. Gereç Yöntem: CZE BCG yöntemleriyle konsantrasyonları 373 hastada ölçüldü. Albümin total seviyeleri, IgG...
Instrumentation is commonly used in spinal surgery to stabilize the fracture. In present study, we aimed compare early and late changes seen bone production degradation products patients with traumatic fracture who had been treated surgically or conservatively.Forty-three were admitted Neurosurgery Department thoracolumbar lumbar this prospective study. Patients divided into two groups of (n = 23) nonsurgically/conservatively 20) patients. The compared conservatively.In conservatively...
AIM: To evaluate vitamin D levels in patients with chronic spontaneous urticaria (CSU), depression and both of them, thus to fi nd out whether may be a common causative factor CSU depression.METHODS: Thirty CSU, 30 depression, healthy volunteers as control group were involved the study.Serum 25-hydroxyvitamin (25(OH) D) these groups measured compared.Correlations between 25(OH)D activity analyzed.RESULTS: Healthy controls' (17.2 ± 8.8 ng/mL) higher than (9.1 5.1 ng/mL), (8.9 6.1 (7.7 4.7 (p...
Acne vulgaris is a common skin disease and has complex pathogenesis. There no enough data related with oxidative stress in acne vulgaris. We purposed to assess total oxidant antioxidant status included 32 patients 35 healthy controls this study. Global Grading System (GAGS) scores were calculated. Serum (TOS) (TAS) levels evaluated index (OSI) was calculated by proportion of the TOS TAS. Mean GAGS 14.08 ± 5.72. duration 33.97 25.99 months. TAS, OSI significantly higher (p=0.010, p=0.021,...
The time of initiating stem cell collection is very important for successful transplantation and determined according to peripheral blood CD34+ count analysed by flow cytometry. In this study, we aimed find the role new complete parameters determine optimal collection. Eighty-six patients who underwent mobilization were included in study. Peripheral cells on same day. Patients with CD 34+ counts ≤ 20/μL > as Group 1 2, respectively. difference CBC between 2 groups relationship these...
Immature granulocytes (IGs) are used as markers of infection and systemic inflammation. We aimed to investigate the diagnostic value IGs in children with urinary tract infections (UTIs). Children their first UTIs were included this observational study. Blood samples obtained before antibiotic therapy. The blood analysis was repeated 2 weeks after treatment ended. In total, 194 (95 febrile UTI, 58 cystitis, 41 controls) included. percentage (IG%) IG count (IGC) measured at time admission...