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Research Areas
- Pharmacological Effects of Natural Compounds
- Mosquito-borne diseases and control
- Hepatocellular Carcinoma Treatment and Prognosis
- Hepatitis B Virus Studies
- HIV Research and Treatment
- Nanoparticle-Based Drug Delivery
- Drug Transport and Resistance Mechanisms
- Natural product bioactivities and synthesis
- Malaria Research and Control
Lifetech Scientific (China)
2021
Guangdong Pharmaceutical University
2020
10.1208/s12249-020-01655-7
article
EN
AAPS PharmSciTech
2020-04-27
Background: Surgery remains the front-line therapeutic strategy to treat early hepatocellular carcinoma (HCC). However, 5-year recurrence rates of HCC patients are high. 10- Hydroxycamptothecin (10-HCPT) is a known anti-HCC agent but its poor solubility and bioavailability have limited clinical use. Objective: In this study, we developed novel nanoliposome encapsulated 10-hydroxycamptothecin modified with glycyrrhetinic acid (GA) TAT peptide (GA/TAT-HCPT-LP) for treatment HCC. Dual GA can...
10.2174/1568026620666200722110244
article
EN
Current Topics in Medicinal Chemistry
2020-07-24
10.1016/j.meegid.2021.104723
article
EN
Infection Genetics and Evolution
2021-01-13
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