A5009061545- Genomic variations and chromosomal abnormalities
- Cancer Genomics and Diagnostics
- Legume Nitrogen Fixing Symbiosis
- Gene expression and cancer classification
- Nitrogen and Sulfur Effects on Brassica
- Plant Disease Resistance and Genetics
- Plant Stress Responses and Tolerance
- Plant Pathogens and Resistance
- Genetic and Environmental Crop Studies
- Chromosomal and Genetic Variations
- Genomics and Phylogenetic Studies
- Biodiesel Production and Applications
- Ion Channels and Receptors
- Plant Pathogenic Bacteria Studies
- Plant pathogens and resistance mechanisms
- Genetic diversity and population structure
- RNA modifications and cancer
- Plant Gene Expression Analysis
- Agricultural Economics and Practices
- Plant Physiology and Cultivation Studies
- Genetics, Bioinformatics, and Biomedical Research
- Microbial Community Ecology and Physiology
- Algal biology and biofuel production
- Cloud Computing and Resource Management
- Molecular Biology Techniques and Applications
Indian Institute of Technology Roorkee
2023-2024
Jawaharlal Nehru University
2019-2022
Gauhati University
2019-2021
National Research Centre on Plant Biotechnology
2021
European Bioinformatics Institute
2021
Punjab Agricultural University
2014-2020
Dr. Yashwant Singh Parmar University of Horticulture and Forestry
2017
Iowa State University
2016
National Science Library
2016
Rajiv Gandhi Technical University
2015-2016
Biological species may remain distinct because of genetic isolation or ecological adaptation, but these two aspects do not always coincide. To establish the nature boundary within a local bacterial population, we characterized sympatric population bacterium Rhizobium leguminosarum by genomic sequencing 72 isolates. Although all strains have 16S rRNA typical R. , they fall into five genospecies criterion average nucleotide identity (ANI). Many genes, on plasmids as well chromosome, support...
Chromothripsis is a recently discovered phenomenon of genomic rearrangement, possibly arising during single genome-shattering event. This could provide an alternative paradigm in cancer development, replacing the gradual accumulation changes with "one-off" catastrophic However, term has been used varying operational definitions, minimal consensus being large number locally clustered copy aberrations. The mechanisms underlying these chromothripsis-like patterns (CTLP) and their specific...
Abstract The European Variation Archive (EVA; https://www.ebi.ac.uk/eva/) is a resource for sharing all types of genetic variation data (SNPs, indels, and structural variants) species. EVA was created in 2014 to provide FAIR access has since grown be primary genomic variants hosting >3 billion records. dbSNP have established compatible global system assign unique identifiers submitted variants. active within the Global Alliance Genomics Health (GA4GH), maintaining, contributing...
Sclerotinia stem rot (Sclerotinia sclerotiorum) is a major disease of Brassica oilseeds. As suitable donors to develop resistant cultivars are not available in crop Brassicas, we introgressed resistance from wild Brassicaceae species, B. fruticulosa. We produced 206 juncea-B. fruticulosa introgression lines (ILs). These were assessed for pollen grain fertility, genome size variations and responses following inoculations under disease-conducive conditions. Of these, 115 ILs showing normal...
A set of 96 Brassica juncea-Erucastrum cardaminoides introgression lines (ILs) were developed with genomic regions associated Sclerotinia stem rot (Sclerotinia sclerotiorum) resistance from a wild Brassicaceous species E. cardaminoides. ILs assessed for their responses to inoculation S. sclerotiorum, over three crop seasons (season I, 2011/2012; II, 2014/2015; III, 2016-2017). Initially, genotyped transferable SSR markers and subsequently through genotyping by sequencing. based association...
Throughout postnatal life in mammals, neural stem cells (NSCs) are located the subventricular zone (SVZ) of lateral ventricles. The greatest diversity neuronal and glial lineages they generate occurs during early a region-specific manner. In order to probe heterogeneity SVZ, we microdissected its dorsal walls at different ages isolated NSCs their immediate progeny based on expression Hes5-EGFP/Prominin1 Ascl1-EGFP, respectively. Whole genome comparative transcriptome analysis revealed...
DNA copy number aberrations (CNAs) can be found in the majority of cancer genomes and are crucial for understanding potential mechanisms underlying tumor initiation progression. Since first release 2001, Progenetix project (http://www.progenetix.org) has provided a reference resource dedicated to provide most comprehensive collection genome-wide CNA profiles. Reflecting application comparative genomic hybridization techniques tens thousands genomes, over past 12 years our data curation...
• Premise of the study: Brassica juncea is a major source edible oil in Indian subcontinent and northern China. It also used as root leaf vegetable China condiment Europe America. There long-standing view that B. originated from multiple hybridization events between rapa nigra hybridizations were always unidirectional with cytoplasmic donor. These conclusions were, however, centered primarily on nuclear markers.• Methods: Two hundred forty-six accessions juncea, rapa, genotyped using...
The delineation of genomic copy number abnormalities (CNAs) from cancer samples has been instrumental for identification tumor suppressor genes and oncogenes proven useful clinical marker detection. An increasing projects have mapped CNAs using high-resolution microarray based techniques. So far, no single resource does provide a global collection readily accessible oncogenomic array data.We here present arrayMap, curated reference database bioinformatics targeting profiling data in human...
Finger millet blast caused by Pyricularia grisea hinders crop's growth and is a serious threat to economic yield. It can lead massive yield losses i.e. up 80%, which cause of major concern. In this study, we evaluated 200 accessions finger at Banda University Agriculture & Technology in Banda, India, under natural conditions determine their resistance against leaf, neck, diseases. Nine displayed strong all forms blast. The genetic variability analysis revealed high phenotypic genotypic...
Abundant availability and easy culture process of algae make it a better resource than other vegetable crops for biodiesel production. The oil (with 21% FFA content) extracted from the unused, mixed in this experiment was used to produce by an' acid esterification followed alkaline esterification' procedure. After confirming properties be within limit ASTM standard, three blends (B10, B20 B30) were an internal combustion engine (Four stroke single cylinder VCR engine) performance observed at...
Abstract Background Chromothripsis is a recently discovered phenomenon of genomic rearrangement, possibly arising during single genome-shattering event. This could provide an alternative paradigm in cancer development, replacing the gradual accumulation changes with “one-off” catastrophic However, term has been used varying operational definitions, minimal consensus being large number locally clustered copy aberrations. The mechanisms underlying these chromothripsis-like patterns (CTLP) and...
Abstract Background Copy number alterations (CNA) play a key role in cancer development and progression. Since more than one CNA can be detected most tumors, frequently co-occurring genetic may point to cooperating related genes. Existing methods for co-occurrence evaluation so far have not considered the overall heterogeneity of per tumor, resulting preferential detection frequent changes with limited specificity each association due high instability many samples. Method We hypothesize that...