A5072484800- Vector-borne infectious diseases
- Hemoglobin structure and function
- Viral Infections and Vectors
- Vector-Borne Animal Diseases
- Legume Nitrogen Fixing Symbiosis
- Zoonotic diseases and public health
- Planarian Biology and Electrostimulation
- Yersinia bacterium, plague, ectoparasites research
- Mosquito-borne diseases and control
- Protist diversity and phylogeny
- Genomics and Phylogenetic Studies
- Hemoglobinopathies and Related Disorders
- Marine Biology and Ecology Research
- Insect and Pesticide Research
- Animal Disease Management and Epidemiology
- Microbial infections and disease research
- Machine Learning in Bioinformatics
- Iron Metabolism and Disorders
- Microbial Community Ecology and Physiology
- Cephalopods and Marine Biology
- French Urban and Social Studies
- Rabies epidemiology and control
- Nematode management and characterization studies
- Marine Invertebrate Physiology and Ecology
- Fractal and DNA sequence analysis
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2015-2025
Épidémiologie des maladies Animales et zoonotiques
2017-2025
Station Biologique de Roscoff
2012-2024
VetAgro Sup
2018-2024
Centre National de la Recherche Scientifique
2012-2024
Sorbonne Université
2009-2024
Université Clermont Auvergne
2019-2024
Université Claude Bernard Lyon 1
2020-2021
Acteurs, Ressources et Territoires dans le Développement
2018-2020
Conseil Régional du Languedoc-Roussillon
2018-2020
A clear picture of animal relationships is a prerequisite to understand how the morphological and ecological diversity animals evolved over time. Among others, placement acoelomorph flatworms, Acoela Nemertodermatida, has fundamental implications for origin evolution various organ systems. Their position, however, been inconsistent in phylogenetic studies using one or several genes. Furthermore, among least stable taxa recent phylogenomic analyses, which simultaneously examine many genes...
Globins occur in all three kingdoms of life: they can be classified into single-domain globins and chimeric globins. The latter comprise the flavohemoglobins with a C-terminal FAD-binding domain gene-regulating globin coupled sensors, variable domains. encompass sequences related to "truncated" hemoglobins 2-over-2 instead canonical 3-over-3 alpha-helical fold.A census 26 archaeal, 245 bacterial 49 eukaryote genomes was carried out. Only approximately 25% archaea have globins, including...
Biological species may remain distinct because of genetic isolation or ecological adaptation, but these two aspects do not always coincide. To establish the nature boundary within a local bacterial population, we characterized sympatric population bacterium Rhizobium leguminosarum by genomic sequencing 72 isolates. Although all strains have 16S rRNA typical R. , they fall into five genospecies criterion average nucleotide identity (ANI). Many genes, on plasmids as well chromosome, support...
Ticks transmit pathogens of medical and veterinary importance are an increasing threat to human animal health. Assessing disease risk developing new control strategies requires identifying members the tick-borne microbiota as well their temporal dynamics interactions.Using high-throughput sequencing, we studied Ixodes ricinus its dynamics. 371 nymphs were monthly collected during three consecutive years in a peri-urban forest. After Poisson lognormal model was adjusted our data set,...
Although most globins, including the N-terminal domains within chimeric proteins such as flavohemoglobins and globin-coupled sensors, exhibit a 3/3 helical sandwich structure, many bacterial, plant, ciliate globins have 2/2 structure. We carried out comprehensive survey of in genomes from three kingdoms life. Bayesian phylogenetic trees based on manually aligned sequences indicate possibility past horizontal globin gene transfers bacteria to eukaryotes. blastp searches revealed presence...
Although legume biodiversity is concentrated in tropical regions, the majority of studies on nodulating bacteria (LNB) are focused cultivated leguminous plants from temperate regions. However, recent works regions tend to indicate that actual diversity LNB largely underestimated. In this study, we report isolation and characterization 68 nitrogen-fixing root nodule collected eight endemic tree species Dalbergia Madagascar. The isolates were characterized by (i) restriction fragment length...
Abstract The potential for disease transmission at the interface of wildlife, domestic animals and humans has become a major concern public health conservation biology. Research in this subject is commonly conducted local scales while regional context neglected. We argue that prevalence infection levels influenced by three mechanisms occurring landscape level metacommunity context. First, (1) dispersal, colonization, extinction pathogens, reservoir or vector hosts, nonreservoir may be due to...
We investigate the genetic structure and molecular selection pattern of a sympatric population Sinorhizobium meliloti medicae. These bacteria fix nitrogen in association with plants genus Medicago. A set 116 isolates were obtained from soil sample, root nodules three groups representing among-species, within-species intraline diversity Medicago genus. Bacteria characterized by sequencing at seven loci evenly distributed along genome both species, covering chromosome two megaplasmids. first...
Using nitrogen-fixing Sinorhizobium species that interact with Medicago plants as a model system, we aimed at clarifying how sex has shaped the diversity of bacteria associated genus on interspecific and intraspecific scales. To gain insights into diversification these symbionts, inferred topology includes different specificity groups which species, based sequences nodulation gene cluster. Furthermore, 126 bacterial isolates were obtained from two soil samples, using truncatula laciniata...
Abstract Background Heterokont algae, together with cryptophytes, haptophytes and some alveolates, possess red-algal derived plastids. The chromalveolate hypothesis proposes that the plastids of all four groups have a monophyletic origin resulting from single secondary endosymbiotic event. However, due to incongruence between nuclear plastid phylogenies, this controversial remains under debate. Large-scale genomic analyses shown be powerful tool for phylogenetic reconstruction but...
Q fever is a worldwide zoonosis caused by Coxiella burnetii. Domestic ruminants are considered to be the main reservoir. Sheep, in particular, may frequently cause outbreaks humans. Because within-flock circulation data essential implementing optimal management strategies, we performed follow-up study of naturally infected flock dairy sheep. We aimed (i) describe C. burnetii shedding dynamics sampling vaginal mucus, feces, and milk, (ii) assess circulating strain diversity, (iii) quantify...
Acoels are simply organized unsegmented worms, lacking hindgut and anus. Several publications over recent years challenge the long-held view that acoels early offshoots of flatworms. Instead a basal position as sister group to all other bilaterian animals was suggested, mainly based on molecular evidence. This led features might reflect those last common ancestor Bilateria, resulted in several evo-devo studies trying interpret evolution using proxy model for "Urbilateria".We describe first...
In the Metazoa, globin proteins display an underlying unity in tertiary structure that belies extraordinary diversity primary structures, biochemical properties, and physiological functions. Phylogenetic reconstructions can reveal which of these functions represent novel, lineage-specific innovations, ancestral are shared with homologous other eukaryotes even prokaryotes. To date, our understanding deuterostomes has been hindered by a dearth genomic sequence data from Ambulacraria...
Due to its proposed basal position in the bilaterian Tree of Life, Acoela may hold key our understanding evolution a number bodyplan features including central nervous system. In order contribute novel data this discussion we investigated distribution α‐tubulin and neurotransmitters serotonin RFamide juveniles adults sagittiferid Symsagittifera roscoffensis . addition, present expression pattern neuropatterning gene SoxB1 Adults exhibit six serotonergic longitudinal neurite bundles an...
Loricifera is a group of small, marine animals, with undetermined phylogenetic relationships within Ecdysozoa (molting protostome animals). Despite their well-known external morphology, data on the internal anatomy loriciferans are still incomplete. Aiming to increase knowledge this enigmatic phylum, we reconstruct for first time three-dimensional myoanatomy loriciferans. Adult Nanaloricus sp. and Higgins larva Armorloricus elegans were investigated cytochemical labeling techniques CLSM. We...
Summary We report on a genomic and functional analysis of novel marine siphovirus, the Vibrio phage SIO‐2. This is lytic for related species great ecological interest including broadly antagonistic bacterium sp. SWAT3 as well notable members Harveyi clade ( V. harveyi ATTC BAA‐1116 campbellii ATCC 25920). SIO‐2 has circularly permuted genome 80 598 bp, which displays unusual features. larger than that most known siphoviruses only 38 116 predicted proteins had homologues in databases. Another...