A5083992248- Mosquito-borne diseases and control
- Viral Infections and Vectors
- Climate Change and Health Impacts
- Dementia and Cognitive Impairment Research
- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- Air Quality and Health Impacts
- COVID-19 epidemiological studies
- COVID-19 and Mental Health
- vaccines and immunoinformatics approaches
- Alzheimer's disease research and treatments
- Escherichia coli research studies
- Malaria Research and Control
- Vibrio bacteria research studies
- Cardiac Arrest and Resuscitation
- Zoonotic diseases and public health
- Blood groups and transfusion
- Influenza Virus Research Studies
- Platelet Disorders and Treatments
- Amyotrophic Lateral Sclerosis Research
- Neurobiology of Language and Bilingualism
- Urban Transport and Accessibility
- Insect and Pesticide Research
- Neurological diseases and metabolism
- Bipolar Disorder and Treatment
University of Santo Tomas
2021-2023
St. Luke's Medical Center
2019-2023
Université Sorbonne Nouvelle
2021
Cities worldwide are facing ever-increasing pressure to develop mitigation strategies for all sectors deal with the impacts of climate change. expected house 70% world’s population by 2050, and developing related resilient health systems is a significant challenge. Because their physical nature, cities’ surface temperatures often substantially higher than that surrounding rural areas, generating so-called Urban Heat Island (UHI) effect. Whilst considerable emphasis has been placed on...
Background: In the midst of competing priorities and limited resources in low-middle-income countries (LMIC), convincing epidemiological evidence is critical for urging governments to develop national dementia plans. The majority primary studies on are from high income (HIC). Implications developing typically extrapolated these outcomes through modeling, meta-analyses, systematic reviews. this study, we directly assessed incidence dementia, disability adjusted life years (DALYs), cost care...
Aim: The aim of this study was to document the ethnobotanical knowledge indigenous Ati tribe in Brgy. Cubay Sur, Malay, Aklan, Philippines. Methods: Semi-structured interviews were conducted March 2019 31 purposively selected key informants determine therapeutic use medicinal plants their traditional medicine. Different indices such as Use Value (UV), Informant Consensus Factor (ICF), and Fidelity level (FL) used plant importance. Results: A total 106 species 48 families 95 genera by treat...
Exposure to traffic-related air pollution is linked with acute alterations in blood pressure (BP). We examined the cumulative short-term effect of black carbon (BC) exposure on systolic (SBP) and diastolic (DBP) BP assessed modification by participant characteristics. SBP DBP were repeatedly measured 152 traffic enforcers. Using a linear mixed-effects model random intercepts, quadratic (QCDL) cubic (CCDL) constrained distributed lag models fitted estimate BC concentration during 10 hours...
With emerging amyloid therapies, documentation of the patient's status to confirm etiology a clinical diagnosis is warranted prior instituting amyloid-based therapy. The Multimer Detection System-Oligomeric Amyloid-β (MDS-OAβ) noninvasive blood-based biomarker utilized measure Aβ oligomerization tendency. We determined difference in MDS-OAβ ratio across groups: (a) no cognitive impairment or subjective (NCI/SCI), (b) Alzheimer's disease (AD), (c) non-AD, and (d) mixed disease-Vascular...
To contribute to the global demand for oral cholera vaccine (OCV), production of Euvichol® was scaled up with elimination thimerosal. demonstrate equivalence variations, a study carried out in Philippines.Healthy male and female adults children Manila were randomized receive two doses weeks apart from either 100L (Comparator) or 600L (Test) variation. Primary secondary immunogenicity endpoints respectively geometric mean titer (GMT) vibriocidal antibodies (two post second dose)...
Our study assessed the impact of using ovitraps with pyriproxyfen on mosquito populations and feasibility human saliva samples to test for seroconversion dengue virus (DENV). We used a quasi-experimental research design by forming intervention (n = 220) control 223) groups in neighboring Taguig City, Philippines, over 4 months. Socio-demographic data, entomological indices, IgG antibodies against DENV were measured. Associations between implementation dosed densities (percentage positive...
<b><i>Background:</i></b> Compared to Western populations, familial frontotemporal lobar degeneration (FTLD) is rare among Asians. Progranulin (GRN) gene mutation, which a major cause of FTLD, likewise rare. We present family with FTLD from the Philippines an autosomal dominant pattern inheritance and GRN mutation briefly review reports mutations in Asia. <b><i>Case Presentation:</i></b> The proband 66 years old progressive nonfluent aphasia...
Dengue is one of the most important vector-borne diseases worldwide and a significant public health problem in tropics. Mosquito control continues to be primary approach reducing disease burden spread dengue virus (DENV). Aside from traditional larviciding adulticiding interventions, autodissemination using pyriproxyfen-treated (AD-PPF) ovitraps promising methods complement existing vector strategies. Our paper assessed efficacy AD-PPF DENV infections two barangays Parañaque City. Using...
<b><i>Background:</i></b> Filipino normative data for neuropsychological tests are lacking. <b><i>Objectives:</i></b> This study aimed to determine the Norming Project (FNP) Neuropsychological Battery, combining Alzheimer’s Disease Assessment Scale – Cognitive (ADAS-Cog) and Test Battery from Uniform Dataset of Center (UDS-ADC). <b><i>Methods:</i></b> We recruited participants 60 years older with normal cognition (MMSE...
<h3>Introduction</h3> Exposure to traffic-related black carbon (BC) has been linked decreased forced expiratory flow (FEF25–75%) and Tiffeneau-Pinelli Index (FEV1/FVC), markers of airway obstruction, in several epidemiological studies. We evaluated whether short-term sub-chronic exposures BC on the road is with obstruction a cohort traffic enforcers. <h3>Methods</h3> studied repeated measurements FEF25–75% FEV1/FVC 158 enforcers from Metropolitan Manila Development Authority (MMDA) Health...
Dengue is a viral mosquito-borne disease that rapidly spreads in tropical and subtropical countries, including the Philippines. One of its most distinguishing characteristics ability Virus (DENV) to easily surpass innate responses body, thus activating B cells adaptive immunity produce virus-specific antibodies. Moreover, Dengvaxia® only licensed vaccine for DENV, but recent studies showed seronegative individuals become prone increased severity hospitalization. Owing this limitation dengue...
Identification of delay barriers to care is essential for an effective and efficient healthcare service delivery. In this study, we described the in among parents patients seeking treatment dengue. We also examined factors affecting severity dengue (dengue with warning signs; severe dengue). A convergent parallel design mixed-method approach using Key Informant Interviews (KII) a survey guided by Three-Delay Model were conducted 24 respondents at National Children's Hospital (NCH). Coding...
There is 35% misdiagnosis of dementia even among specialists and knowledge amyloid Positron Emission Tomography (PET) results led to diagnostic shift from Alzheimer's Disease (AD) non-AD vice versa with change in management up 63%. Amyloid PET not widely available accessible. Multimer Detection System (MDS) detects plasma oligomeric beta (OAβ) discriminative accuracy comparable PET. We investigated whether MDS-OAβ could differentiate AD other etiologies. This cross-sectional study 212...
Dengue is a viral mosquito-borne disease that rapidly spreads in tropical and subtropical countries, including the Philippines. One of its most distinguishing characteristics ability Virus (DENV) to easily surpass innate responses body, thus activating B cells adaptive immunity produce virus-specific antibodies. Moreover, Dengvaxia&reg; only licensed vaccine for DENV, but recent studies showed seronegative individuals become prone increased severity hospitalization. Owing this limitation...
Dengue infection is one of the most important vector-borne diseases worldwide and a significant public health problem in tropics. Mosquito control continues to be primary approach reducing disease burden dengue virus (DENV) spread. Aside from traditional larviciding adulticiding interventions, autodissemination using pyriproxyfen-treated (AD-PPF) ovitraps promising methods complement existing vector strategies. Our paper assessed efficacy AD-PPF DENV two barangays Para&ntilde;aque City....
Cities worldwide are facing ever-increasing pressure to develop mitigation strategies for all sectors deal with the impacts of climate change. expected house 70% world&rsquo;s population by 2050 and developing related resilient health systems is a significant challenge. Because their physical nature, cities&rsquo; surface temperatures often substantially higher than that surrounding rural areas, generating so-called Urban Heat Island (UHI) effect. Whilst considerable emphasis has...
Exposure to traffic-related air pollution is linked with acute alterations in blood pressure (BP). We examined the cumulative short-term effect of black carbon (BC) exposure on systolic (SBP) and diastolic (DBP) BP assessed modification by participant characteristics. SBP DBP were repeatedly measured 152 traffic enforcers. Using a linear mixed-effects model random intercepts, quadratic (QCDL) cubic (CCDL) constrained distributed lag models fitted estimate BC concentration during 10-hours...
Our study assessed the impact of using ovitraps with pyriproxyfen on mosquito populations and feasibility human saliva samples to test for seroconversion dengue virus (DENV). We used a quasi-experimental research design by forming intervention (n=220) control (n=223) groups in neighboring Taguig City, Philippines, over four months. Socio-demographic data, entomological indices, IgG antibodies against DENV were measured. Associations between implementation dosed densities (percentage positive...