A5073249120- Protist diversity and phylogeny
- Microbial Community Ecology and Physiology
- Paleontology and Stratigraphy of Fossils
- Genomics and Phylogenetic Studies
- Marine Invertebrate Physiology and Ecology
- Myxozoan Parasites in Aquatic Species
- Geology and Paleoclimatology Research
- Mesenchymal stem cell research
- Coastal wetland ecosystem dynamics
- Cellular Mechanics and Interactions
- Micro and Nano Robotics
- Evolution and Genetic Dynamics
- Aquatic Ecosystems and Phytoplankton Dynamics
- Slime Mold and Myxomycetes Research
- Geological formations and processes
- Neurogenetic and Muscular Disorders Research
- Lymphatic System and Diseases
- Angiogenesis and VEGF in Cancer
- Enhanced Oil Recovery Techniques
- Marine Toxins and Detection Methods
- Muscle Physiology and Disorders
Universidade de São Paulo
2016-2024
Mississippi State University
2023-2024
Universidade Cidade de São Paulo
2019
Protists, the micro-eukaryotes that are neither plants, animals nor fungi build up greatest part of eukaryotic diversity on Earth. Yet, their evolutionary histories and patterns still mostly ignored, complexity overlooked. Protists often assumed to keep stable morphologies for long periods time (morphological stasis). In this work, we test paradigm taking Arcellinida testate amoebae as a model. We taxon-rich phylogeny based two mitochondrial (COI NADH) one nuclear (SSU) gene, reconstruct...
Heterotrophic protists are vital in Earth's ecosystems, influencing carbon and nutrient cycles occupying key positions food webs as microbial predators. Fossils molecular data suggest the emergence of predatory microeukaryotes transition to a eukaryote-rich marine environment by 800 million years ago (Ma). Neoproterozoic vase-shaped microfossils (VSMs) linked Arcellinida testate amoebae represent oldest evidence heterotrophic microeukaryotes. This study explores phylogenetic relationship...
Peripheral arterial disease (PAD) affects millions of people and compromises quality life. Critical limb ischemia (CLI), which is the most advanced stage PAD, can cause nonhealing ulcers strong chronic pain, it shortens patients' life expectancy. Cell-based angiogenic therapies are becoming a real therapeutic approach to treat CLI. Pericytes cells that surround vascular endothelial reinforce vessel integrity regulate local blood pressure metabolism. In past decade, researchers also found...
Heterotrophic microbial eukaryotes play a pivotal role in aquatic and terrestrial ecosystems, contributing to carbon nutrient cycles. These microorganisms, capable of phagocytosis, act as predators bacterial communities other microeukaryotes, occupying significant position complex food webs. The timing the origin diversification heterotrophic microeukaryotes remain unclear. Fossil evidence molecular data suggest that emergence predatory transition eukaryote-dominant marine environment...
Rab GTPase is a paralog-rich gene family that controls the maintenance of eukaryotic cell compartmentalization system. Diverse eukaryotes have varying numbers paralogs. Currently, little known about evolutionary pattern in most major 'supergroups'. Here, we present comprehensive phylogenetic reconstruction 'supergroup' Amoebozoa, diverse lineage represented by unicellular and multicellular organisms. We demonstrate Amoebozoa conserved 20 23 ancestral GTPases predicted to be last common...
Arcellinida are free-living lobose amoebae that produce an outer shell (test). Here, we describe a conspicuous new species, Arcella gandalfi sp. nov, from Brazilian continental waters, along with morphological and biometrical characterization. Test diameter test height on average 81 71 respectively. This species has apical conical extension, which differentiates it other species. A. seems to be closely-related brasiliensis, due the distinct marginal ring (test brim) present only in these two...
Arcellinida is ascending in importance protistology, but description of their diversity still presents multiple challenges. Furthermore, applicable tools for surveillance these organisms are developing stages. Importantly, a good database that sets correspondence between molecular barcodes and species morphology lacking. Cytochrome oxidase (COI) has been suggested as the most relevant marker discrimination Arcellinida. However, some major groups lacking COI sequence. Here we expand sequences...
Coexistence usually are exceeding the explicable rate by competitive exclusion principle. Since pioneer Gause, many studies have used protist microcosm systems to study exclusion. We explored a two-species system with testate-amoebae: (Arcella intermedia and Pyxidicula operculata), where is expected occur. determined their growth curves individually under interaction. state-space model represent dynamics calculated posterior population sizes simulating competition dynamics. Contrarily our...
Arcella, a diverse understudied genus of testate amoebae is member Tubulinea in Amoebozoa group. Transcriptomes are powerful tool for characterization these organisms as they an efficient way characterizing the protein-coding potential genome. In this work, we employed both single-cell and clonal populations transcriptomics to create reference transcriptome Arcella. We compared our results with annotations Dictyostelium discoideum, model Amoebozoan. assembled pool 38 Arcella intermedia...
Arcellinida is an Amoebozoa lineage characterized by the presence of external shell.A comprehensive cyto-morphological description shell structure and formation (thecagenesis) process has been generated due to publications in time span more than a century.Recently, few works have advanced our understanding thecagenesis or discussed this rich literature; however, several aspects are still puzzles, as remains relationship between genes morphogenesis.Here we present overview literature about...
Abstract Background Peripheral arterial disease (PAD) affects millions of people and compromises quality life. Critical limb ischemia (CLI), which is the most advanced stage PAD, can cause nonhealing ulcers strong chronic pain, it shortens patients’ life expectancy. Cell-based angiogenic therapies are becoming a real therapeutic approach to treat CLI. Pericytes cells that surround vascular endothelial reinforce vessel integrity regulate local blood pressure metabolism. In past decade,...