Fábio Silva da Silva

ORCID: 0000-0001-7510-6641
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About
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Research Areas
  • Mosquito-borne diseases and control
  • Viral Infections and Vectors
  • Malaria Research and Control
  • Insect symbiosis and bacterial influences
  • Dengue and Mosquito Control Research
  • Zoonotic diseases and public health
  • Vector-borne infectious diseases
  • Toxoplasma gondii Research Studies
  • Vector-Borne Animal Diseases
  • Insect Resistance and Genetics
  • Insect behavior and control techniques
  • Antimicrobial Peptides and Activities
  • Veterinary Medicine and Surgery
  • Insect Pest Control Strategies
  • Machine Learning in Bioinformatics
  • vaccines and immunoinformatics approaches
  • Insect Utilization and Effects
  • Yersinia bacterium, plague, ectoparasites research
  • Virology and Viral Diseases
  • Microbial infections and disease research
  • Primate Behavior and Ecology
  • HIV Research and Treatment
  • Healthcare Regulation
  • Urological Disorders and Treatments
  • Rabies epidemiology and control

Instituto Evandro Chagas
2021-2025

Ministério da Saúde
2023-2025

Universidade do Estado do Pará
2020-2025

Amazon (United States)
2024

Universidade Federal de Pelotas
2018

Abstract Bats play an essential role in maintaining ecosystems. Their unique characteristics increase the likelihood of interactions with various species, making them a potential source for emergence and spread infectious diseases. Hantaviruses are continuously expanding their range hosts. This study presents identification partial genome associated Hantavirus samples collected from neotropical bats. We conducted metagenomic using Carollia perspicillata Maranhão, Brazil. Tissue fragments...

10.1038/s41598-024-56808-6 article EN cc-by Scientific Reports 2024-03-15

A wide diversity of pathogenic mosquito-borne viruses circulate in the Brazilian Amazon, and intense deforestation can contribute to spread these viruses. In this context, study aimed investigate viral mosquitoes genera Aedes, Culex, Haemagogus, Sabethes from a transition area between Cerrado, Caatinga biomes Brazil. Metagenomic high-throughput sequencing was used characterize virome 20 mosquito pools. total 15 virus-like genomes were identified, comprising species genomically close...

10.3390/genes14071443 article EN Genes 2023-07-14

Dengue virus 2 (DENV-2) seriously contributes to dengue-related mortality. It includes five nonsylvatic genotypes, with cosmopolitan being the most widespread a significant contribution total number of DENV-2 cases globally. In South America, genotype was first recorded in 2019 Madre de Dios, Peru, and then Goiás (Midwest Brazil) November 2021. this study, we tested 163 human serum samples from Acre (Northern collected during DENV outbreak between 2020 2021 for all genotypes by RT-qPCR. Of...

10.3390/tropicalmed8060325 article EN cc-by Tropical Medicine and Infectious Disease 2023-06-17

West Nile virus is characterized as a neurotropic pathogen, which can cause fever and transmitted by mosquitoes of the genus Culex. In 2018, Instituto Evandro Chagas performed first isolation WNV strain in Brazil from horse brain sample. The present study aimed to evaluate susceptibility orally infected Cx. quinquefasciatus Amazon region become transmit isolated 2018. Oral infection was with blood meal artificially WNV, followed analysis infection, dissemination, transmission rates, well...

10.3390/tropicalmed8040217 article EN cc-by Tropical Medicine and Infectious Disease 2023-04-06

Wild rodents serve as crucial reservoirs for zoonotic viruses. Anthropogenic and environmental disruptions, particularly those induced by mining activities, can destabilize rodent populations facilitate the emergence of viral agents. In Canaã dos Carajás Curionópolis regions Brazil, significant changes have occurred due to expansion, potentially creating conditions conducive rodent-associated diseases. This study aimed investigate diversity in wild captured Curionópolis, Pará, between 2017...

10.3389/fmicb.2024.1502462 article EN cc-by Frontiers in Microbiology 2025-01-07

In the history of yellow fever (YF) outbreaks in Brazil, howler monkeys (Alouatta sp.) and marmosets (Callithrix have been among most affected genera, exhibiting significant hepatic injuries similar to those seen humans. However, limited information exists regarding virus (YFV) infection their central nervous system (CNS). To address this gap, an epidemiological study was conducted assess tissue changes, viral detection, cytokine profiles brains both neotropical primate species when they are...

10.3390/v17030386 article EN cc-by Viruses 2025-03-07

The Quilombola community of Abacatal, located in Ananindeua, the state Pará, has characteristics that favor proliferation mosquitoes. Faunal surveys environmental preservation areas are essential for understanding dynamics these vectors, whose epidemiological implications significant. Uncontrolled human activities have an impact on temperature, humidity, and rainfall. aim this study was to survey diversity mosquito species Abacatal. Field collections were carried out over 10 days, during...

10.3390/insects16040397 article EN cc-by Insects 2025-04-10

Dengue virus serotype 2 (DENV-2) is responsible for dengue epidemics on a global scale and associated with severe cases of the disease. This study conducted phylogenetic investigation DENV-2 isolates from 2017 to 2021 originating northern states Brazil. A total 32 samples were analyzed, including 12 Acre, 19 Roraima, one Tocantins. Only lineage Asian-American genotype cosmopolitan observed: Lineage 1, (connection Puerto Rico); 5, Peru). Our results provide important data regarding DENV...

10.3390/tropicalmed9010017 article EN cc-by Tropical Medicine and Infectious Disease 2024-01-09

The genus Orthopodomyia Theobald, 1904 (Diptera: Culicidae) comprises 36 wild mosquito species, with distribution largely restricted to tropical and temperate areas, most of which are not recognized as vectors epidemiological importance due the lack information related their bionomy involvement in cycle transmission infectious agents. Furthermore, evolutionary relationships completely understood, reflecting scarcity genetic about genus. Therefore, this study, we report first complete...

10.3390/genes15070874 article EN Genes 2024-07-03

Abstract The genus Haemagogus (Diptera: Culicidae) comprises species of great epidemiological relevance, involved in transmission cycles the Yellow fever virus and other arboviruses South America. So far, only janthinomys has complete mitochondrial sequences available. Given unavailability information related to aspects evolutionary biology molecular taxonomy this genus, we report here, first sequencing mitogenomes albomaculatus , leucocelaenus spegazzinii tropicalis . showed an average...

10.1038/s41598-020-73790-x article EN cc-by Scientific Reports 2020-10-12

The Culicidae family is distributed worldwide and comprises about 3587 species subdivided into the subfamilies Anophelinae Culicinae. This first description of complete mitochondrial DNA sequences from Aedes fluviatilis, Aedeomyia squamipennis, Coquillettidia nigricans, Psorophora albipes, ferox. mitogenomes showed an average length 15,046 pb 78.02% AT content, comprising 37 functional subunits (13 protein coding genes, 22 tRNAs, two rRNAs). most common start codons were ATT/ATG, TAA was...

10.3390/genes12121983 article EN Genes 2021-12-14

Background: Orthoflavivirus ilheusense (ILHV) is a member of the Flaviviridae family. It was first isolated in 1944 from pools Aedes serratus and Psorophora ferox mosquitoes; however, it has also been detected species genus Culex, such as Cx. portesi coronator. The objective this study to examine vector competence quinquefasciatus mosquitoes ILHV infection subsequent transmission virus through their saliva during feeding on blood. Methods: F1 generation females (Ananindeua/PA) were orally...

10.3390/life14040427 article EN cc-by Life 2024-03-22

Viruses of the Lyssavirus genus are classified into several genotypes (GT1 to GT7), which only GT1 (classic rabies virus-RABV) has a cosmopolitan distribution and circulates in Brazil. is subdivided antigenic variants (AgV) maintained independent cycles with narrow host range distinct geographic distributions, namely, AgV1 AgV2 found dogs, AgV3 vampire bats Desmodus rotundus, AgV4 AgV6 non-hematophagous Tadarida brasiliensis Lasiurus cinereus, common variant marmoset (Callithrix jacchus),...

10.3389/fvets.2023.1257558 article EN cc-by Frontiers in Veterinary Science 2023-09-29

As part of a continuous effort to investigate the viral communities associated with wild mammals at human–animal interface in an Amazonian metropolitan region, this study describes detection novel rodent-borne arterivirus. A sample containing pooled organs Oecomys paricola was submitted RNA sequencing, and four sequences taxonomically assigned as related Arteriviridae family were recovered, corresponding almost complete genome nearly 13 kb summed. In phylogenetic analysis standard domains...

10.3390/v15051150 article EN cc-by Viruses 2023-05-11

The largest outbreak of sylvatic yellow fever virus (YFV) in eight decades was recorded Brazil between 2016-2018. Besides human and NHP surveillance, the entomo-virological approach is considered as a complementary tool. For this study, total 2904 mosquitoes Aedes, Haemagogus Sabethes genera were collected from six Brazilian states (Bahia, Goiás, Mato Grosso, Minas Gerais, Pará, Tocantins) grouped into 246 pools, which tested for YFV using RT-qPCR. We detected 20 positive pools 5 1 Bahia,...

10.3390/tropicalmed8060329 article EN cc-by Tropical Medicine and Infectious Disease 2023-06-20

Aedes aegypti is a mosquito native to the African continent, which now widespread in tropical and subtropical regions of world. In many regions, it represents major challenge public health, given its role cycle transmission important arboviruses, such as Dengue, Zika, Chikungunya. Considering epidemiological importance Ae. aegypti, present study sequenced partial mitochondrial genome sample collected municipality Balsas, Brazilian state Maranhão, followed by High Throughput Sequencing...

10.3390/insects14120938 article EN cc-by Insects 2023-12-11

Abstract The West Nile virus is characterized as a neurotropic pathogen that causes the fever. It transmitted by mosquitoes, mainly of Culex genus. In 2018, Evandro Chagas Institute carried out first isolation WNV strain from horse brain sample and in 2021 same institute also isolated pool mosquitoes spp . Carajás region (Pará). Thus, this study aimed to determine vectorial competence quinquefasciatus Amazon Brazil for transmission Brazilian strain. Oral infection Cx. females belonging F1...

10.21203/rs.3.rs-603135/v1 preprint EN cc-by Research Square (Research Square) 2021-06-15

O vírus linfotrópico de células T humanas (HTLV) (Retroviridae: Deltaretrovirus) possui características zoonóticas por derivar linhagens símias (STLV) em função provavelmente do contato interespécie, com quadro clínico caracterizado linfomas, mielopatia, linfocitose e doenças neurológicas leves. desenvolvimento estudos epidemiológicos permitem assim compreender a distribuição atual das diferentes vírus, principalmente partir da utilização metodologias ferramentas biologia molecular,...

10.34119/bjhrv7n4-106 article PT Brazilian Journal of Health Review 2024-07-17

A hidronefrose refere-se à dilatação da pelve e dos cálices renais, devido a uma obstrução urinária renal ou pós-renal que induz atrofia progressiva do parênquima renal. ocorrência de em filhotes é rara, portanto, este estudo tem o objetivo relatar um caso idiopática, sem causa aparente, felino três meses idade. O animal foi atendido no Hospital Veterinário Universidade Federal Pelotas, com histórico distensão abdominal. Ao exame ultrassonográfico, observou-se grave rim esquerdo, grau I...

10.55905/oelv22n8-039 article PT cc-by-nc OBSERVATÓRIO DE LA ECONOMÍA LATINOAMERICANA 2024-08-07

Loreto virus (LORV) is an insect-specific classified into the proposed taxon Negevirus. It was originally described in Iquitos, Peru, 1977. Here, we describe three novel LORV genomes obtained from isolates of pooled samples Trichoprosopon digitatum, Aedes (Ochlerotatus) fulvus, and Limatus durhamii collected Ilhéus—Bahia, 2014. Samples were submitted to RNA sequencing on Illumina platform recover genome. The presented, average, 81.5% nucleotide identity 92.6% global amino acid with reference...

10.3390/v16111674 article EN cc-by Viruses 2024-10-25
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