The levels of malondialdehyde (MDA), glutathione peroxidase (GSH‐Px) and superoxide dismutase (SOD‐1) were measured in the red blood cells (RBC) 34 patients with acute ischemic hemispheric stroke on first seventh day after their onset, compared 30 control individuals matched for sex, age risk factors. Within 24 h stroke, SOD GSH‐Px activities significantly decreased MDA elevated subjects. Decrease increase showed significant correlation infarct size, initial severity assessed by NIH scale...

To assess the clinical and genetic characteristics of children diagnosed with retinoblastoma (RB) at Gazi University Faculty Medicine's Department Pediatric Oncology.All cases RB received treatment follow-up in Ophthalmology Oncology Department, October 2016 to May 2021 were evaluated retrospectively. The RB1 gene was analyzed by next-generation sequencing (NGS) technique DNAs obtained from peripheral blood samples patients.This study included 53 67 RB-affected eyes during period. mean age...

OBJECTIVE: In this study, we aimed to retrospectively evaluate the significance of new hematological parameters in diagnosis inflammatory process acute pancreatitis children diagnosed with (AP) and recurrent (ARP). This is first study literature assessing (Red cell distribution width (RDW), red calcium ratio (RDWCaR), neutrophile lymphocyte (NLR), monocyte (LMR), platelet (PLR), Red (RDWPR) mean volume (MPV)) retrospectively. MATERIAL AND METHODS: The medical records 55 patients, who were...

The aim of this study was to evaluate the sociodemographic properties, clinical, laboratory, and radiological findings, diagnosis patients with head neck lymphadenopathy (LAP) who applied Department Pediatric Oncology Medical Faculty Gazi University.

Abstract Thymic tumors are very rare neoplasms in children and account for less than 1% of mediastinal pediatric patients. One‐third the patients present with symptoms related to compression tumor mass on surrounding anatomic structures, paraneoplastic syndromes such as myasthenia gravis, pure red cell aplasia, acquired hypogammaglobulinemia, connective tissue disorders, which rarely occur thymic tumors. Herein, we report a case carcinoma mimicking disease symmetrical polyarthritis...

Combined immunodeficiency due to CD70 deficiency is characterized by increased susceptibility infections, hypogammaglobulinemia, and malignancy. These patients typically present with chronic Epstein Barr virus (EBV) viremia, severe EBV-related hemophagocytic lymphohistiocytosis, lymphoproliferation, Hodgkin non-Hodgkin lymphomas. Plasmablastic lymphoma (PBL) an extremely rare malignancy in all ages predominantly seen male adults human infection. EBV infection, immunosuppression, solid organ...

The aim of this study was to evaluate the prognostic value textural parameters primary tumors, serum lactate dehydrogenase (LDH), D -dimer, and ferritin in high-risk neuroblastoma patients.The imaging findings 22 patients (14 girls 8 boys; age, 36.6 ± 34.2 [range: 5 138] months) who underwent 18-fluorodeoxyglucose positron emission tomography/computed tomography for staging before therapy between 2009 2020 were retrospectively evaluated. Positron tomography-derived metabolic data (maximum...

Introduction: Abnormal uterine bleeding (AUK) is a term used for changes in menstrual pattern, duration, or amount.In adolescent girls, it associated with the immature hypothalamo-pituitary-ovarian axis, disorders, infections, endocrine systemic diseases, vagina-cervix-uterus and problems related to ovary drugs.There are different approaches between disciplines this assessment.In our study, we aimed share results ÖzGiriş: Anormal uterin kanama (AUK), menstrüel düzeni, süresi veya...

Purpose: The aim of this study is to investigate the clinical and radiological features, especially importance T2-FLAIR mismatch sign response treatment patients diagnosed with diffuse midline gliomas (DMG) in our center.

The spinal cord compression causes irreversible long-term permanent neurological sequelae. This study aims to increase awareness of childhood cancers that cause by comparing histopathological diagnosis, treatments, and survival rates the literature.Seventy-three patients (38 male, 35 female) with compression, among 1085 diagnosed solid tumors at Gazi University Department Pediatric Oncology between 1991 2021 were retrospectively evaluated.The mean time onset complaints diagnosis was 27.5±...

Psoriasis is an inflammatory skin disease in which the cells and molecules of innate adaptive immunity are involved pathogenesis. Aplastic anemia a bone marrow deficiency syndrome that characterized by extreme reduction number blood as result failure hematopoiesis. Allogenic hematopoietic stem cell transplantation promising treatment for Anemia it important to note other comorbid diseases like psoriasis- since both have some common pathogenetic mechanisims- might achieve remission after...

Cyclopentolate is frequently used as a mydriatic agent during ophthalmological examinations in childhood and hypersensitivity reactions associated with this drug are rare. We aim to report an infant who experienced anaphylaxis due cyclopentolate eye drops.A nine-month-old girl, was being followed up diagnosis of retinoblastoma, presented for consultation urticaria, cough, stridor, dyspnea that developed after the administration topical eyes. The patient diagnosed treated adrenaline. During...

Amplitude integrated electroencephalography (aEEG) is a user friendly technique suitable for long term continuous monitoring of cerebral electrical background activity. It increasingly being used in high risk neonates intensive care units. Newer two-channel aEEG monitors by providing data from both side the brain may increase sensitivity detection unilateral injury. Here we report critically ill preterm neonate with intracranial hemorrhage who was monitored 3 weeks continuously. Seizures...

The aim of this study was to evaluate the prognostic value PET-derived metabolic features and textural parameters primary tumors in pediatric sarcoma patients.The imaging findings 43 patients (14 girls 29 boys; age 11.4 ± 4.4 years) who underwent 18-fluorodeoxyglucose positron emission tomography (PET)/computed for staging prior therapy between 2005 2020 were retrospectively evaluated. diagnoses osteosarcoma 10, rhabdomyosarcoma Ewing 23 patients. PET data obtained. Cox proportional hazards...

In this study, children with vitamin B12 deficiency anemia (V-B12DA) and control subjects were evaluated for erythrocyte glutathione peroxidase, catalase superoxide dismutase enzyme activities, glutathione, malondialdehyde, serum total sialic acid, antioxidant status, cobalt, chromium, copper, selenium, vanadium, zinc, iron, lead, magnesium, calcium, sodium, potassium, chloride, phosphorus levels, the associations of these variables assessed. The study included 50 V-B12DA subjects. It was...

Factor XIII deficiency is an extremely rare type among bleeding diathesis. In factor deficiency, normal results of coagulation screening tests are expected. It usually does not cause spontaneous bleeding. Apart from diathesis, it may delayed wound healing and recurrent abortions in women. Here, we present a 32-year-old case with severe congenital who had uncomplicated pregnancy birth regular replacement therapies. A patient history abortion at the 11th week her first pregnancy, applied to...

Burkitt and Burkitt-like lymphomas constitute 40% of childhood are malignancies that require urgent diagnosis treatment.Here, we present a case 10-year-old male patient who was diagnosed with lymphoma applied to the dentist complaints pain in left upper molars facial swelling for 2 weeks.Magnetic resonance imaging showed significant soft tissue around mandible maxillary tooth roots lower jaws.The histopathological examination gingival biopsy.Diffuse bone marrow involvement hyperuricemia due...

OBJECTIVE: Although there have been remarkable developments regarding stem-cell transplantation (HSCT) in Turkey, but the number of people who would like to be stem cell donors is not yet at desired level. The present study aimed assess effect training delivered by specialists on thoughts and decisions health employees working our center being HSCT donors. MATERIAL AND METHODS: Employees sector received any were included study. A half-hour collective for all participants was General...

To determine if previous histological grading systems were sufficient or unreliable with a limited repository of modern techniques.The pathology reports pediatric neurosurgery patients between 2019-2022 accessed. Data on that needed unattainable further molecular investigation extracted. noted from electronic archives, including their sex, age, histologic grade, location, resection type, survival, and therapy.Out 61 surgeries, 17 for proper 2022 World Health Organization (WHO) diagnosis....

Background/Aims: Optic pathway gliomas (OPGs) are low-grade histologically represented by pilocytic astrocytoma (PA) in 90% of cases, can develop from any part the visual pathways such as optic nerve, chiasm, tract, or radiations which frequently involve hypothalamus. OPGs account for 3–5% childhood central nervous system (CNS) tumors and about 2% pediatric glial lesions. believed to be most prevalent intracranial tumor patients with neurofibromatosis type 1 (NF-1) occur 15–20% NF-1 cases....