Aleksei V. Zamalutdinov

ORCID: 0000-0001-7524-8877
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About
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Research Areas
  • Steroid Chemistry and Biochemistry
  • Biochemical and Structural Characterization
  • Pharmacogenetics and Drug Metabolism
  • Protease and Inhibitor Mechanisms
  • CRISPR and Genetic Engineering
  • Plant Disease Resistance and Genetics
  • Peptidase Inhibition and Analysis
  • Hormonal Regulation and Hypertension
  • Advanced biosensing and bioanalysis techniques
  • Genomics and Phylogenetic Studies
  • RNA Interference and Gene Delivery
  • Soybean genetics and cultivation

Skolkovo Institute of Science and Technology
2025

Lomonosov Moscow State University
2020-2022

<title>Abstract</title> Background Genotype-by-sequencing (GBS) is a cost-effective method for large-scale genotyping, widely used across various species, particularly those with large genomes. A critical aspect of GBS lies in the selection restriction enzymes genome digestion and optimization data analysis pipelines. However, few studies have comprehensively examined combined effects enzyme choice pipeline configuration. Results In this study, we created libraries using three commonly...

10.21203/rs.3.rs-5821852/v1 preprint EN cc-by Research Square (Research Square) 2025-01-20

CRISPR/Cas systems (Clustered regularly interspaced palindromic repeats / CRISPR-associated) are rapidly becoming a commonplace and popular tool for gene editing in research clinical contexts. However, the quality of experiments depends heavily on guide RNA (gRNA) design; therefore, reliable, easy, rapid method verifying gRNA cleavage efficacy is necessary. Engineered nuclease-induced translocations (ENIT) an easy cost-efficient verification efficacy, which involves tracking induced...

10.1016/j.mex.2020.101104 article EN cc-by MethodsX 2020-01-01
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