A5082777730- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Dysphagia Assessment and Management
- Sleep and Wakefulness Research
- Tracheal and airway disorders
- Voice and Speech Disorders
- Sinusitis and nasal conditions
- Respiratory and Cough-Related Research
- Nasal Surgery and Airway Studies
- Allergic Rhinitis and Sensitization
- Airway Management and Intubation Techniques
- Ocular Surface and Contact Lens
- Probiotics and Fermented Foods
- Temporomandibular Joint Disorders
- Oral microbiology and periodontitis research
- Olfactory and Sensory Function Studies
- Facial Rejuvenation and Surgery Techniques
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Asthma and respiratory diseases
- Non-Invasive Vital Sign Monitoring
- Tumors and Oncological Cases
- Antimicrobial Peptides and Activities
- Cerebral Palsy and Movement Disorders
- Dermatologic Treatments and Research
- Oral and Maxillofacial Pathology
Antwerp University Hospital
2013-2025
University of Antwerp
2012-2025
Sint Lucas Andreas Hospital
2014
To study the possible predictive value of drug-induced sleep endoscopy (DISE) in assessing therapeutic response to implanted upper airway stimulation (UAS) for obstructive apnea (OSA). During DISE, artificial is induced by midazolam and/or propofol, and pharyngeal collapse patterns are visualized using a flexible fiberoptic nasopharyngoscope. The level (palate, oropharynx, tongue base, hypopharynx/epiglottis), direction (anteroposterior, concentric, lateral), degree (none, partial, or...
To describe upper airway (UA) collapse patterns during drug-induced sleep endoscopy (DISE) in a large cohort of patients with sleep-disordered breathing (SDB) and to assess associations anthropometric polysomnographic parameters.Observational study.A total 1,249 [age 47 ± 10 y; apnea-hypopnea index (AHI) 18.9 15.3/h; body mass (BMI) 27.2 3.7 kg/m(2)] underwent polysomnography DISE. DISE findings were categorized the following UA levels: palate, oropharynx, tongue base, hypopharynx. The...
Summary The aim of this study was to assess the value drug‐induced sleep endoscopy ( DISE ) using a custom‐made simulation bite in maximal comfortable protrusion MCP mandible, prediction treatment outcome for obstructive apnea OSA with mandibular advancement device MAD ). Two hundred patients (74% male; age 46 ± 9 years; apnea–hypopnea index [ AHI ] 19 13 h −1 sleep; body mass BMI 27 4 kg m −2 sleep‐disordered breathing underwent . One and thirty‐five an established diagnosis commenced...
Abstract Purpose The objective of this randomized controlled trial was to assess the additional effect a chest-worn sleep position trainer (SPT) in patients with residual supine-dependent obstructive apnea (sdOSA) under mandibular advancement device (MAD) therapy. Methods Baseline and follow-up polysomnography MAD were performed. Twenty sdOSA therapy underwent two consecutive polysomnographies: one SPT combination + MAD. Data are presented as median (quartile 1, quartile 3). Results reduced...
To determine variations in interobserver and intraobserver agreement of drug-induced sleep endoscopy (DISE) a cohort experienced versus nonexperienced ear, nose, throat (ENT) surgeons. Prospective, blinded study. Ninety-seven ENT surgeons (90 with DISE; seven experienced) observed six different DISE videos were asked to score the upper airway (UA) level (palate, oropharynx, tongue base, hypopharynx, epiglottis), direction (anteroposterior, concentric, lateral), degree collapse (none; partial...
Mandibular advancement device (MAD) outcome varies between patients. We hypothesized that upper airway collapse sites, patterns, and degrees assessed during baseline drug-induced sleep endoscopy (DISE) affect MAD outcome.One hundred patients with obstructive apnea (OSA) were included underwent type 1 polysomnography. was fitted intraorally at fixed 75% maximal protrusion. A total of 72 completed 3-month follow-up polysomnography DISE. Response defined as apnea-hypopnea index (AHI) reduction...
The current COVID-19 or Sars-CoV-2 pandemic increased awareness of hyposmia anosmia, as this can be an accompanying symptom.In mild cases, anosmia without rhinorrhea the only presenting symptom infection.Timely identification lead to early detection otherwise asymptomatic carriers.History taking and essential clinical assessment with appropriate protective measures performed in patients whom is suspected.Patients nasal obstruction should considered suspect initiate testing self-isolation.As...
Summary Mandibular advancement device (MAD) treatment outcome for obstructive sleep apnea (OSA) is variable and patient dependent. A global, clinically applicable predictive model lacking. Our aim was to combine characteristics obtained during drug‐induced endoscopy (DISE), awake nasendoscopy, computed tomography scan‐based computational fluid dynamic (CFD) measurements in one multifactorial model, explain MAD outcome. total of 100 patients with OSA were prospectively recruited treated a at...
Background: Double-blinded placebo-controlled trials have revealed the efficacy of mepolizumab and omalizumab in treatment chronic rhinosinusitis with nasal polyps (CRSwNP). However, real-world (RWE) data, data on therapeutic response level disease control for both biologicals are lacking. Methodology: 167 patients uncontrolled severe CRSwNP, meeting national reimbursement criteria, were included follow-up over 24 weeks. Primary outcomes changes congestion (NCS), polyp score (NPS),...
Surgical interventions, like barbed reposition pharyngoplasty (BRP), are a valuable alternative for patients with obstructive sleep apnea (OSA) who unable to tolerate continuous positive airway pressure (CPAP). However, predicting surgical success remains challenging, partly due the contribution of non-anatomical factors. Therefore, combined medical treatment acetazolamide, known stabilize respiratory drive, may lead superior results. This double-blind, parallel-group randomized controlled...
The aim of this pilot study was to evaluate the clinical effectiveness subjective titration versus objectively guided during polysomnography (PSG) and drug-induced sleep endoscopy (DISE) in mandibular advancement device (MAD) therapy for patients with obstructive apnea (OSA).In cross-over study, underwent three procedures randomized order: (1) titration, (2) PSG-guided using a remotely controlled positioner (RCMP) (3) DISE-assisted RCMP. After each procedure, used MAD 1 month at targeted...
Editorial-BellIt is quite possible that we are very likely going to see a greater dependence on remote data collection of this type as the sophistication and reliability units improves.It certainly behooves us find ways adapt our treatment modalities successfully interface with these newer modes.The future success dental professionals in arena depends ability be nimble new technologies they emerge.
Abstract Background The amount of mandibular protrusion is a key factor in optimizing the efficacy advancement device (MAD) therapy an individual patient diagnosed with obstructive sleep apnea. This process called titration and generally based on resolution subjective symptoms like snoring and/or daytime sleepiness as function protrusion. An objective approach uses remotely controlled positioner (RCMP) during full-night polysomnography (PSG), analogy continuous positive airway pressure...
Obstructive sleep apnea (OSA) is a disorder characterized by repetitive episodes of partial or complete obstruction the upper airway during sleep. Continuous positive pressure (CPAP) method used as first-line treatment for obstructive (OSA). However, intolerance and resistance to CPAP can limit its long-term effectiveness. Alternative treatments are available, such Mandibular Advancement Devices (MADs), positional therapy, surgery, maxillomandibular osteotomy. often less efficient in...