Karim Abdelaal

ORCID: 0000-0001-7577-1238
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About
Contact & Profiles
Research Areas
  • Neuroscience and Neuropharmacology Research
  • Retinal Development and Disorders
  • Visual perception and processing mechanisms
  • Neural dynamics and brain function
  • Glaucoma and retinal disorders
  • Mental Health Research Topics
  • Functional Brain Connectivity Studies
  • Employer Branding and e-HRM
  • Neurogenesis and neuroplasticity mechanisms
  • Digital Marketing and Social Media
  • Genetics and Neurodevelopmental Disorders
  • Organizational and Employee Performance
  • Mitochondrial Function and Pathology

Duke University
2024

Duke University Hospital
2024

Duke Medical Center
2024

Howard Hughes Medical Institute
2024

Massachusetts Institute of Technology
2021-2022

Sultan Abdul Halim Mu'adzam Shah International Islamic University
2022

Recent increases in human longevity have been accompanied by a rise the incidence of dementia, highlighting need to preserve cognitive function an aging population. A small percentage individuals with pathological hallmarks neurodegenerative disease are able maintain normal cognition. Although molecular mechanisms that govern this neuroprotection remain unknown, exhibit resilience (CgR) represent unique source therapeutic insight. For both humans and animal models, living enriched,...

10.1126/scitranslmed.abd7695 article EN Science Translational Medicine 2021-11-03

Study of the neural deficits caused by mismatched binocular vision in early childhood has predominantly focused on circuits primary visual cortex (V1). Recent evidence revealed that neurons mouse dorsolateral geniculate nucleus (dLGN) can undergo rapid ocular dominance plasticity following monocular deprivation (MD). It remains unclear, however, whether long-lasting attributed to MD during critical period originate thalamus. Using vivo two-photon Ca 2+ imaging dLGN afferents superficial...

10.1523/jneurosci.1626-19.2019 article EN cc-by-nc-sa Journal of Neuroscience 2019-11-25

Digital technologies are new trends in recent times that have revolutionarily changed. business models, work, conduct business, and corporate strategies. As a result, the human resources (HR) function has evolved to incorporate digital world its design thinking, strategizing implementing. The hotel industry is one of sectors move at an unbelievably fast-pace developing countries due increase tourism industry. Yet, on contrary, heavily increasing burden environment. Thus, because huge number...

10.55862/asbjv3i2a001 article EN 2022-12-20

ABSTRACT Monocular deprivation (MD) during the juvenile critical period leads to long-lasting impairments in binocular function and visual acuity. The site of these changes has been widely considered be cortical. However, recent evidence indicates that integration may first occur dorsolateral geniculate nucleus thalamus (dLGN), raising question whether MD produce deficits dLGN integration. Using vivo two-photon Ca 2+ imaging afferents excitatory neurons superficial layers primary cortex...

10.1101/484774 preprint EN cc-by-nc bioRxiv (Cold Spring Harbor Laboratory) 2018-12-02

SUMMARYA clinical hallmark of Alzheimer’s disease is significant reductions in the white matter connecting two cerebral hemispheres, as well correlated activity between anatomically corresponding bilateral brain areas. However, underlying circuit mechanisms and cognitive relevance cross-hemispheric communication remain poorly studied. Here, we show that novelty discrimination behavior activated neurons enhanced homotopic synchronized gamma oscillations visual cortex. Cross-hemispheric...

10.2139/ssrn.3887797 article EN SSRN Electronic Journal 2021-01-01
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