A5063402800- Coordination Chemistry and Organometallics
- Catalytic Cross-Coupling Reactions
- Asymmetric Synthesis and Catalysis
- Synthetic Organic Chemistry Methods
- Synthesis and Reactivity of Heterocycles
- Synthesis and Catalytic Reactions
- Axial and Atropisomeric Chirality Synthesis
- Radical Photochemical Reactions
- Alkaloids: synthesis and pharmacology
- Organoboron and organosilicon chemistry
- Synthesis and Properties of Aromatic Compounds
- Molecular Sensors and Ion Detection
- Toxic Organic Pollutants Impact
- Organometallic Complex Synthesis and Catalysis
- Chemical Synthesis and Analysis
- Catalytic C–H Functionalization Methods
- Supramolecular Chemistry and Complexes
- Synthesis and Reactions of Organic Compounds
- Advanced Synthetic Organic Chemistry
- Microbial Natural Products and Biosynthesis
- Environmental Toxicology and Ecotoxicology
- Effects and risks of endocrine disrupting chemicals
UiT The Arctic University of Norway
2019-2023
University of Stavanger
2018-2023
University of Warsaw
2019
Centre for Arctic Gas Hydrate, Environment and Climate
2019
Justus-Liebig-Universität Gießen
2019
University of Amsterdam
2019
Forschungszentrum Jülich
2019
Klinik und Poliklinik für Psychosomatik und Psychotherapie
2019
University Hospital Cologne
2019
Max Planck Institute for Metabolism Research
2019
Over the past decades, organic chemists have focussed on developing new approaches to directed C–H functionalisations, where site selectivity is steered by presence of a directing group (DG). Nonetheless, in recent years, more and non-directed strategies are being developed circumvent requisite group, making functionalisations generic. This short review focuses latest developments palladium-catalysed aromatic compounds. 1 Introduction 2 C–C Bond Formation 2.1 Arylation 2.2 Alkylation 2.3...
Tricyclic polycyclic aromatic hydrocarbons (PAHs) are believed to be the primary toxic components of crude oil. Such compounds including phenanthrene known have direct effects on cardiac tissue, which lead malformations during organogenesis in early life stage fish. We tested a suite 13 alkyl-phenanthrenes compare uptake and developmental toxicity haddock (Melanogrammus aeglefinus) embryos gastrulation/organogenesis beginning at 2 days post fertilization via passive dosing. The were their...
A general method for the regioselective synthesis of a series ortho-substituted chrysenyl N,N-diethyl-O-carbamates by directed ortho-metalation (DoM) strategy is reported. The starting O-carbamates were prepared from corresponding chrysenols, available oxidative photochemical cyclization or remote metalation tactics. Chrysen-1-yl and chrysene-3-yl ring site selectivity anionic ortho-Fries rearrangement (AoF) protocols, with s-BuLi/TMEDA, followed electrophilic quench using selection...
Polycyclic aromatic hydrocarbons (PAHs) with six and seven rings were synthesized via directed metalation cross-coupling of chrysenyl N,N-diethyl carboxamides o-tolyl methylnaphthalenyl derivatives. In the presence competing ortho sites, site selectivity in iodination amides by (DoM) was influenced lithium base. The catalyst ligand bite angle presumably important sterically hindered bulky PAHs. Subsequent remote biaryls under standard conditions at elevated temperatures afforded various...
New polycyclic hexahydrobenzo[<i>c</i>]acridines were synthesized in excellent yields by intramolecular [4+2]-cycloaddition reactions of aldimines derived from aromatic amines and 2-(4-methylpent-3-en-1-yl)benzaldehyde acetonitrile the presence 10 mol% bismuth(III) chloride. The reaction is highly diastereoselective, giving <i>cis</i>-fused benzoacridine derivatives preferentially.
Abstract This review covers the latest developments in synthesis of cryptophane host molecules since publication last extensive by Brotin and Dutasta 2009. The literature has been categorized according to synthetic method for generating core we also emphasize emerging late‐stage functionalization approaches. strategies towards cryptophanes can be broadly into well‐established direct‐ (two‐step), template‐ coupling (or capping) methods. examples covered this mainly highlight template‐based...
Cleavage of Catechol Monoalkyl Ethers by Aluminum Triiodide-Dimethyl Sulfoxide HO RO AlI 3 (1.1 equiv) DMSO (1.1-2.5 MeCN, 80 °C, 18 h 30 substrates 34-100% yields