A5018251008- Virus-based gene therapy research
- Animal Virus Infections Studies
- Herpesvirus Infections and Treatments
- Poxvirus research and outbreaks
- Mesenchymal stem cell research
- Carbon and Quantum Dots Applications
- Viral Infections and Immunology Research
- Animal Disease Management and Epidemiology
- Parvovirus B19 Infection Studies
- Cytomegalovirus and herpesvirus research
- Conducting polymers and applications
- Congenital Anomalies and Fetal Surgery
- Electrochemical sensors and biosensors
- Microbial infections and disease research
Henan University
2025
Yanbian University
2022-2024
Feline panleukopenia virus (FPV) is a widespread and highly infectious pathogen in cats with high mortality rate. Although Yanji has developed cat breeding industry, the variation of FPV locally still unclear.This study aimed to isolate investigate epidemiology between 2021 2022.A strain was isolated from F81 cells. Cats suspected infection (n = 80) 2022 were enrolled this study. The capsid protein 2 (VP2) amplified. It cloned into pMD-19T vector transformed competent Escherichia coli...
Feline mesenchymal stem cells (fMSCs) are well known for their robust differentiation capabilities and commonly used in studying immune-related diseases cats. Despite importance, the susceptibility of fMSCs to viral infections remains uncertain. This study aimed assess feline adipose-derived (fAD-MSCs) umbilical cord-derived (fUC-MSCs) common viruses, including coronavirus (FCoV), herpesvirus type 1 (FHV-1), panleukopenia virus (FPV). The results demonstrated that both FCoV FHV-1 were able...
Gosling plague (GP) is an acute and hemorrhagic infectious disease caused by goose parvovirus (GPV). The industry suffers significant economic losses as a result of GP, which found to be widespread worldwide, with high rates morbidity mortality. Our group developed novel technique for detecting GPV nanoparticle-assisted polymerase chain reaction (nanoPCR) the characterization its specificity sensitivity. It was using traditional (PCR) nanoparticles. findings this study revealed that nanoPCR...
Bovine infectious rhinotracheitis (IBR), caused by bovine alphaherpesvirus 1 (BoAHV1), poses significant challenges to the global cattle industry due its high contagiousness and economic impact. In our study, we successfully isolated a BoAHV1 strain from suspected infected nasal mucus samples in Yanji city, revealing genetic similarities with strains Sichuan, Egypt, USA, while Xinjiang, Beijing, Hebei, Inner Mongolia showed more distant associations, indicating potential cross-border...
Epidemiological surveys revealed that 33 of the 93 samples were positive for FHV-1, with gD gene these exhibiting low variation, high homology, and no critical amino acid mutation. Feline herpesvirus type 1 (FHV-1), also known as feline viral rhinotracheitis (FVR) virus, is one main causes URT disease in cats. All cats can become hosts spread this affects protection rare animals. Nasal swabs from collected at five veterinary clinics Yanji City 2022 to 2024. The purpose study was isolate...
Feline panleukopenia (FP) is a severe viral illness caused by the feline virus (FPV), putting sectors like companion cat breeding and endangered conservation at risk. The has high morbidity fatality rate found all over world. We created novel FPV assay using nanoPCR technology assessed method's specificity sensitivity. approach amplified 345 bp nucleic acid fragment with minimum detection limit of 7.97 × 102 copies/μL, which about 100 times greater than traditional PCR. collected anal swabs...
Canine parvovirus 2 (CPV2) causes one of the most serious canine viral infections, with high mortality in young dogs. In 2014, 2019, and 2021, we determined genetic sequences CPV2 strains obtained from 39 fecal samples collected Yanbian Korean Autonomous Prefecture Jilin Province China. Sequence alignments were performed using major capsid protein (VP2) gene; these had nucleotide (>97.4%) amino acid (>95.6%) identity. All contained Ser297Ala Tyr324Ile mutations. Our survey indicated a...
Gosling plague (GP) is caused by goose parvovirus (GPV) gosling acute, subacute, and septic infectious diseases, commonly known as plague. At present, the prevention control of GP at home abroad mainly adopts method immunizing female geese with attenuated vaccine. Goslings can be immunized, but there are still phenomenon dispersive virus virulence reverse. It, therefore, urgent to develop a new safe effective The recombinant avian pox vaccines rFPV-GoIFNγ, rFPV-GPV-VP3 rFPV-GoIFNγ-VP3 were...