A5058809799- Ferroptosis and cancer prognosis
- Glioma Diagnosis and Treatment
- Immune cells in cancer
- RNA modifications and cancer
- Diabetic Foot Ulcer Assessment and Management
- Pelvic and Acetabular Injuries
- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Cancer Immunotherapy and Biomarkers
- Maternal and fetal healthcare
- Respiratory viral infections research
- Epigenetics and DNA Methylation
- Cancer Mechanisms and Therapy
- Extracellular vesicles in disease
- Cardiovascular Disease and Adiposity
- Immune Cell Function and Interaction
- Sepsis Diagnosis and Treatment
- Cardiovascular Health and Disease Prevention
- Orthopedic Surgery and Rehabilitation
- Renal and Vascular Pathologies
- Neuroinflammation and Neurodegeneration Mechanisms
- Dental Implant Techniques and Outcomes
- Gastrointestinal Bleeding Diagnosis and Treatment
- Foot and Ankle Surgery
- Abdominal Surgery and Complications
China Medical University
2012-2025
First Hospital of China Medical University
2012-2025
Southern Medical University
2023
Nanfang Hospital
2023
Aberrant expression of coding genes the V-ATPase subunits has been reported in glioma patients that can activate oncogenic pathways and result worse prognosis. However, predictive effect a single gene is not specific or sensitive enough. In this study, by using series bioinformatics analyses, we identified five (ATP6V1C2, ATP6V1G2, TCIRG1, ATP6AP1 ATP6AP2) were related to patient Based on these genes, sub-classified into different prognosis clusters, which C1 cluster performed better...
Glioblastoma (GBM) is the most common malignant brain tumor and aggressive type of glioma, characterized by strong invasive potential rapid recurrence despite severe treatment methods, such as maximal resection followed chemotherapy radiotherapy. Thrombospondin-1 (THBS1) was first discovered in platelets subsequent studies have indicated its functions development several cancers, including breast cancer, melanoma, gastric cervical cancer GBM. However, to best our knowledge, expression...
Abstract Serine Incorporator 2 (SERINC2) is a transmembrane protein that incorporates serine into membrane lipids. The function of SERINC2 in tumors has been reported, but the role gliomas not fully understood. RNA-sequencing data from Cancer Genome Atlas (TCGA) (530 cases low-grade glioma (LGG) and 173 glioblastoma multiforme (GBM)) microarray Gene Expression Omnibus (GEO) (Accession No. GSE16011, 284 were included) acquired. Bioinformatics analysis was performed as primary method to...
Background: Glioblastoma multiforme (GBM) is the most common malignant tumor in central nervous system with poor prognosis and unsatisfactory therapeutic efficacy. Considering high correlation between tumors angiogenesis, we attempted to construct a more effective model angiogenesis-related genes (ARGs) better predict response prognosis. Methods: The ARG datasets were downloaded from NCBI-Gene Molecular Signatures Database. gene expression data clinical information obtained TCGA CGGA...
Glioma is the most common primary brain tumor and glioblastoma multiforme (GBM) malignant glioma with worst prognosis. T cell immune regulator 1 (TCIRG1) constitutes V<sub>0</sub>a<sub>3</sub> subunit of vacuolar ATPase (V‑ATPase), function V‑ATPase in tumors, such as breast cancer, melanoma hepatocellular carcinoma, has been reported. However, effect TCIRG1 on GBM remains to be fully elucidated. mRNA levels different cancer types corresponding normal tissues were extracted from Oncomine...
Background Minimally invasive reduction and fixation of intra‐articular calcaneal fractures poses great challenges for orthopaedic surgeons. The aim the present study was to report technical points, evaluate efficacy minimally internal assisted by temporary limb reconstruction system (LRS) external fixator fractures, propose indications our protocol. Methods In this retrospective study, a series 34 consecutive closed displaced involving articular surface were treated technology between June...
Objective To evaluate the clinical values of intra-operative spinal digital subtraction angiography and selective intra-arterial injection methylene blue for in surgical treatment dural ateriovenous fistula (SDAVF). Methods Four patients underwent microsurgical combined with DSA SDAVF our hospital from January 2015 to December were chosen. Selective was applicated three them. The data efficacy these retrospectively analyzed. Results Intra-operative performed successfully no...
Objective Based on systematic inflammatory response syndrome (SIRS)and having spleen T-lymphocytes of rats as indicators,which were typical representatives in immune function and process inflammation,this research aimed at investigating the effects hyperbaric oxygen (HBO) normal with SIRS.Methods Male healthy SD randomly divided into five groups:the A group,the B groups,the latter group was treated saline solution (5 ml/kg),the C,D E groups zymosan (500 mg/kg).The animals D given a single...
Objective: The optimal operative strategy in patients with asymptomatic severe carotid artery stenosis undergoing coronary bypass grafting (CABG) is unknown. We sought to investigate the safety of arterial shunting during simultaneous CABG and endarterectomy (CEA). Methods: clinical data synchronous combined CEA First Hospital China Medical University between March 2017 July 2019 was retrospectively studied. Patients ≥70% according NASCET (North American Symptomatic Carotid Endarterectomy...
Abstract Reconstruction of abdominal wall defects is still a big challenge in surgery, especially where there insufficient fascia muscular or excessive tension the emergency and life-threatening scenarios. Indeed, concept damage control surgery has been advanced management both traumatic nontraumatic surgical settings. The strategy requires abridged quick back to intensive care units (ICU) for aggressive resuscitation. In laparotomy, patients are left with open abdomen provisional closure...