A5003298117- Diabetes Treatment and Management
- Lipid metabolism and disorders
- Cancer, Lipids, and Metabolism
- Metabolism, Diabetes, and Cancer
- Biochemical Acid Research Studies
- Angiogenesis and VEGF in Cancer
- Microbial metabolism and enzyme function
- Lipoproteins and Cardiovascular Health
- Liver Disease Diagnosis and Treatment
- Diet and metabolism studies
- Apelin-related biomedical research
- Parkinson's Disease Mechanisms and Treatments
- Nutritional Studies and Diet
- Neurological Disorders and Treatments
- Immune cells in cancer
- Pancreatic function and diabetes
- Alcoholism and Thiamine Deficiency
- Natural Antidiabetic Agents Studies
- Cardiovascular Function and Risk Factors
- Adipokines, Inflammation, and Metabolic Diseases
- Regulation of Appetite and Obesity
- Diabetes and associated disorders
- Cancer Risks and Factors
- Thermoregulation and physiological responses
- Antiplatelet Therapy and Cardiovascular Diseases
Kazakh National Medical University
2021
West Kazakhstan Marat Ospanov State Medical University
2014-2018
Kazakhstan Medical University
2017
Poznan University of Medical Sciences
2015
<b><i>Background/Aims:</i></b> Recent experimental research revealed that statins at low doses induce angiogenesis, which in turn may be related to the course of atherosclerosis. There are no clinical studies evaluating effect ‘low-dose' on serum levels angiogenesis regulators diabetic subjects. We aimed explain how modify concentrations two potent proangiogenic factors, vascular endothelial growth factor (VEGF) and basic fibroblast (bFGF), patients with type 2...
Recent data suggest that thymic output, which provides the naive T cells necessary for normal functioning of T-cell-dependent immunosurveillance cellular immunity including anti-cancer protection, can be disturbed in course type 2 diabetes. Metformin, an anti-diabetic drug commonly confirmed as agent with many potential activities, might helpful this immune correction. The profile output was evaluated current study on basis signal-joint T-cell receptor excision circle (sjTREC) concentration...
The pro-atherogenic role of RANTES, a chemokine expressing pleiotropic activities, in the course type 2 diabetes-related atherosclerosis has been well documented. However, it is not known which factors primarily influence serum RANTES levels patients with diabetes. Our aim was to investigate relationships between several be related an increased risk and diabetic patients. A total 168 subjects were examined, included 138 diabetes 30 non-diabetic controls. Measurements venous, fasting, plasma...
Limited data suggested that inclusion of a strength component into endurance exercises might intensify the beneficial effect training. However, available is limited. Therefore, we aimed to compare and endurance-strength training on anthropometric parameters, endothelial function, arterial stiffness, antioxidant status, inflammatory markers in abdominally obese women without serious comorbidities. A total 101 were recruited randomly divided (n = 52) 49) groups. During three-month...
The CD3+56+ cells are a small but significant population of T lymphocytes encompassing NKT-like and NKT cells, which may play the essential role at very early stages atherosclerotic plaque development. frequency activity in atherosclerosis-inducing dysglycaemic disease (diabetes type 2 or pre-diabetes) is largely unknown.We analysed cell count, granzyme, perforin annexin V profiles peripheral blood from group patients with pre-diabetes, diabetes non-dysglycaemic controls. Measurements were...
The aim of this study was to investigate the influence statins on secretion angiogenesis mediators by peripheral blood mononuclear cells (PBMCs) derived from patients suffering type 2 diabetes. group comprised 30 participants and included: 10 statin-treated with diabetes, statin-free diabetic subjects, non-diabetic individuals. PBMCs isolated were cultured in vitro standard conditions an environment mimicking hyperglycemia. Culture supernatants evaluated for VEGF, MCP-1, Il-10, Il-12 flow...
Cardiovascular risk in the course of diabetes depends greatly on glycemic variability which is even more significant than chronic hyperglycemia. Optimal management involves a multidisciplinary approach focused particular decreasing atherosclerosis. Therefore, our purpose was to evaluate impact dapagliflozin glucose excursions and related proatherogenic changes aortic wall. Animal model type 2 rich-fat/STZ rats used. Wistar were randomized into 3 groups: dapagliflozin-treated with excursions,...
People commonly use new technologies to promote a healthy lifestyle and help them lose weight through nutritional programs. This study evaluated the quality of individualized meal plans offered by dietary apps.Ten apps that offer personalized were selected for study, weekly generated, values diets calculated. The Healthy Diet Indicator Quality Index estimated.Significant differences between observed in calculated energy (p<0.0001) macronutrients (p<0.05), content vitamins (vitamin A, E, K,...