A5079384576- Ophthalmology and Visual Impairment Studies
- Corneal surgery and disorders
- Glaucoma and retinal disorders
- Ocular Surface and Contact Lens
- Ergonomics and Musculoskeletal Disorders
- Retinal Diseases and Treatments
- Ocular Infections and Treatments
- Leaf Properties and Growth Measurement
- Intraocular Surgery and Lenses
Sun Yat-sen University
2020-2024
State Key Laboratory of Ophthalmology
2023
To investigate the 2-year efficacy of atropine, orthokeratology (ortho-k) and combined treatment on myopia. explore factors influencing efficacy.An age-stratified randomised controlled trial. Children (n=164) aged 8-12 years with spherical equivalent refraction -1.00 to -6.00 D were stratified into two age subgroups randomly assigned receive placebo drops+spectacles (control), 0.01% atropine+spectacles (atropine), ortho-k+placebo or treatment. Axial length was measured at baseline visits 6,...
Purpose To investigate the long-term effect of orthokeratology (ortho-k) on choroidal thickness and contour in myopic children. Methods Subjects were from a conducted 2-year randomised clinical trial. Children (n=80) aged 8–12 years with spherical equivalent refraction −1.00 to −6.00D randomly assigned control group (n=40) ortho-k (n=40). Optical coherence tomography images collected at baseline, 1-month, 6-month, 12-month, 18-month 24-month visits, then choroid calculated. Axial length (AL)...
To investigate the efficacy and safety of orthokeratology (ortho-k) repeated low-level red-light (RLRL) therapy in treating poor responders ortho-k myopic children.
Abstract Purpose To develop and validate a standardized prediction model aiming at 1‐year axial length elongation to guide the orthokeratology lens practice. Methods This retrospective study was based on medical records of myopic children treated with orthokeratology. Individuals aged 8–15 years ( n = 1261) were included divided into primary cohort 757) validation 504). Feature selection primarily performed sort out influential predictors by high‐throughput extraction. Then, developed using...
This study used three-dimensional (3D) modelling to investigate scleral profiles in myopic eyes and compare them with emmetropic eyes.In this prospective observational study, the of 151 participants were analysed using corneoscleral profile module (CSP) Pentacam HR. Non-rotationally symmetrical ellipsoids fitted anterior sagittal height. Three radii analysed, namely nasal-temporal (Rx), superior-inferior (Ry) anterior-posterior (Rz) orientations. Additionally, area index (AI) aspherical...
Purpose: Long-term axial length (AL) shortening in myopia is uncommon but noteworthy. Current understanding on the condition limited due to difficulties case collection. The study reported percentage, probability, and time course of long-term AL myopic orthokeratology based a large database. Methods: This reviewed 142,091 medical records from 29,825 subjects single-hospital database that were collected over 10 years. was defined as change −0.1 mm or less at any follow-up beyond 1 year....
Abstract Purpose This study aims to reveal the relationship between posterior ocular contour and subsequent progression of myopia in children. Methods Children aged 8–12 years with received baseline measurements were instructed wear their glasses every day return for a follow‐up visit after one year. Axial length other parameters measured using noncontact biometer. The eye was calculated analysed based on images from spectral domain optical coherence tomography (SD‐OCT). Univariate...
Purpose. To determine three-year change of the corneal biomechanical parameter stress-strain index (SSI) in schoolchildren aged 7– 9 years and their correlation with refractive error axial length (AL). Methods. This is a prospective cohort study. Data AL, error, SSI were collected at baseline 3-year follow-up for 217 schoolchildren. SSI, measured via visualization Scheimpflug technology (Corvis ST), IOLMaster biometry, cycloplegic refraction. Three changes its association AL analyzed....
Abstract Purpose To investigate the effect of COVID‐19 home confinement on efficacy interventions for controlling myopia, and to select effective therapies control myopia during confinement. Method Children ( n = 164) aged 8–12 years with spherical equivalent refraction −1.00 −6.00 diopters were stratified into two age subgroups randomly allocated control, 0.01% atropine, orthokeratology (ortho‐k) atropine combined ortho‐k (ACO) groups. Axial length (AL) was measured at baseline, 6‐, 12‐,...