Shujiao Zhu

ORCID: 0000-0001-7624-902X
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About
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Research Areas
  • Bacteriophages and microbial interactions
  • Viral gastroenteritis research and epidemiology
  • Vibrio bacteria research studies
  • Microbial infections and disease research
  • Genomics and Phylogenetic Studies
  • Probiotics and Fermented Foods
  • Salmonella and Campylobacter epidemiology
  • Enterobacteriaceae and Cronobacter Research
  • Respiratory viral infections research
  • Bacterial Genetics and Biotechnology
  • Animal Virus Infections Studies

Jiangsu Academy of Agricultural Sciences
2019-2024

Phages are strong antibacterial agents commonly used in the food industry, especially phage cocktails that cause much stronger and more stable effects. This study aimed to identify characterize three absolutely lytic phages of E. coli isolated from poultry farms. O18-011 EK010 were classified Podoviridae family, genus Kuravirus, Phage vB_EcoM_005 was Myoviridae Dhakavirus. The bacteriolytic activity all an almost wide range temperature, pH, salt concentrations. All exhibited extensive...

10.1016/j.lwt.2021.112836 article EN cc-by-nc-nd LWT 2021-11-22

Enterohemorrhagic Escherichia coli (EHEC) O157:H7 and Enterotoxigenic E. (ETEC) are important foodborne pathogens, causing serious food poisoning outbreaks worldwide. Bacteriophages, as novel antibacterial agents, have been increasingly exploited to control pathogens. In this study, a broad-host range lytic phage vB_EcoM_SQ17 (SQ17), was isolated, characterized, evaluated for its potential bacterial counts in vitro three different matrices (milk, raw beef, fresh lettuce). Phage SQ17 capable...

10.3389/fmicb.2022.929005 article EN cc-by Frontiers in Microbiology 2022-08-05

The development of phage-resistant bacteria is a challenging problem for phage therapy. However, our knowledge resistance mechanisms still limited.

10.1128/msphere.01286-20 article EN cc-by mSphere 2021-03-05

Abstract Many studies have shown the efficacy of phage therapy in reducing gastrointestinal pathogens. However, it is unclear whether phages can successfully colonize gut when administered an adequate amount for a long time. About 1 × 10 8 PFU/mL purified lytic PA13076 or temperate BP96115 were fed daily to mice via drinking water over 31 days, elucidate distribution tract. At day 16 and 31, six different segments tract with their contents, including stomach, duodenum, jejunum, ileum, cecum,...

10.1186/s43014-020-00029-7 article EN cc-by Food Production Processing and Nutrition 2020-07-29
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