A5071487261- Eosinophilic Esophagitis
- Gastroesophageal reflux and treatments
- Helicobacter pylori-related gastroenterology studies
- Eosinophilic Disorders and Syndromes
- IL-33, ST2, and ILC Pathways
- Inflammatory Bowel Disease
- Asthma and respiratory diseases
- Gastrointestinal motility and disorders
- Advanced biosensing and bioanalysis techniques
- Acute Lymphoblastic Leukemia research
- Autoimmune and Inflammatory Disorders Research
- Sphingolipid Metabolism and Signaling
- Gastrointestinal disorders and treatments
- Digestive system and related health
- RNA Interference and Gene Delivery
- MicroRNA in disease regulation
- Lysosomal Storage Disorders Research
- Urticaria and Related Conditions
- Pharmaceutical studies and practices
- Inflammatory mediators and NSAID effects
University of Missouri–Kansas City
2019-2025
Children's Mercy Hospital
2017-2024
University of Missouri
2023
University of Kansas
2023
Eosinophilic esophagitis (EoE) is an eosinophilic-predominant inflammation of the esophagus diagnosed by upper endoscopy and biopsies. A non-invasive cost-effective alternative for management EoE being researched. Previous studies assessing utility fractional exhaled nitric oxide (FeNO) in were low powered. None investigated contribution eosinophilic stomach duodenum to FeNO.To assess FeNO as a biomarker esophageal monitoring disease activity.Patients aged 6-21 years undergoing scheduled...
Introduction Chronic inflammation of the gastrointestinal tissues underlies inflammatory disorders, leading to tissue damage and a constellation painful debilitating symptoms. These disorders include bowel diseases (Crohn’s disease ulcerative colitis), eosinophilic (eosinophilic esophagitis duodenitis). Gastrointestinal can often present with overlapping symptoms necessitating use invasive procedures give an accurate diagnosis. Methods This study used peripheral blood mononuclear cells from...
Identification of disease and therapeutic biomarkers remains a significant challenge in the early diagnosis effective treatment juvenile idiopathic arthritis (JIA). In this study, plasma metabolomic profiling was conducted to identify disease-related metabolic associated with JIA. Plasma samples from treatment-naïve JIA patients non-JIA reference underwent global across discovery (60 JIA, 60 non-JIA) replication (49 38 cohorts. Univariate analysis identified metabolites (q-value ≤ 0.05),...
Abstract Chronic inflammation of the gastrointestinal tissues underlies inflammatory disorders, leading to tissue damage and a constellation painful debilitating symptoms. These disorders include bowel diseases (Crohn’s disease ulcerative colitis), eosinophilic (eosinophilic esophagitis duodenitis). Gastrointestinal can often present with overlapping symptoms necessitating use invasive procedures give an accurate diagnosis. This study used peripheral blood mononuclear cells from individuals...